CD4 News and Research

RSS

MSD announces Phase 2b results of doravirine therapy in untreated patients with HIV-1 infection

Merck Sharp & Dohme Ltd. MSD (known as Merck & Co., Inc. in the United States and Canada), today announced the presentation of results from a Phase 2b clinical trial evaluating the safety and efficacy of once daily oral doravirine, an investigational next-generation non-nucleoside reverse transcriptase inhibitor (NNRTI), plus tenofovir/emtricitabine (TDF/FTC) compared to efavirenz plus TDF/FTC in previously untreated patients with HIV-1 infection.

4 Nov 2014

New research sheds light on future efforts to eradicate HIV from the body in human patients

Where does HIV hide? Antiretroviral drugs can usually control the virus, but can't completely eliminate it. So any strategy to eradicate HIV from the body has to take into account not only the main group of immune cells the virus targets, called CD4 or helper T cells, but other infected cells as well.

3 Nov 2014

Daktari receives NIH SBIR grant to develop point-of-care sickle cell diagnostic test

Daktari Diagnostics, in collaboration with Harvard University, the Medical University of South Carolina, and the University of Zambia in Lusaka, is thrilled to announce that it has been awarded a Small Business Innovation Research grant by the National Institute of Health for a point-of-care sickle cell diagnostic test.

23 Sep 2014

New breast cancer vaccine provides evidence of immunotherapy in preventing disease recurrence

A new breast cancer vaccine candidate, (GP2), provides further evidence of the potential of immunotherapy in preventing disease recurrence. This is especially the case for high-risk patients when it is combined with a powerful immunotherapy drug.

8 Sep 2014

New blood test provides fast, accurate diagnosis of tuberculosis in children

A new blood test provides a fast and accurate tool to diagnose tuberculosis in children, a new proof-of-concept study shows. The newly developed test (TAM-TB assay) is the first reliable immunodiagnostic assay to detect active tuberculosis in children.

1 Sep 2014

Pilot study shows that anti-cancer drug can activate hidden HIV

A pilot study by HIV researchers from Aarhus University and Aarhus University Hospital in Denmark has shown that an anti-cancer drug can activate hidden HIV.

23 Jul 2014

HIV detected in Mississippi baby after apparent cure

In November 2013, it was reported that an infant (known as the “Mississippi baby”) had been in prolonged remission from HIV and was apparently cured. However, after 2 years without taking antiretroviral therapy and having no evidence of the virus, the child now has detectable levels of HIV.

11 Jul 2014

Mississippi baby: Infant seemingly cured of HIV has detectable levels of HIV

The child known as the "Mississippi baby"-an infant seemingly cured of HIV that was reported as a case study of a prolonged remission of HIV infection in The New England Journal of Medicine last fall-now has detectable levels of HIV after more than two years of not taking antiretroviral therapy without evidence of virus, according to the pediatric HIV specialist and researchers involved in the case.

11 Jul 2014

GSMA announces mobile ecosystem partnership to provide mHealth services to women, children

The GSMA today announced that its Mobile for Development mHealth programme has launched a new cross-ecosystem partnership designed to provide a range of mHealth services to women and children, with a particular focus on nutrition, across Sub-Saharan Africa.

30 Jun 2014

Study finds link between high CD4 cell counts and reduced ischemic stroke risk in people with HIV

A 15-year study found that HIV-positive individuals had a 40 percent increased risk of ischemic stroke, however stroke rates were nearly the same for HIV-positive individuals with high CD4 cell counts as for HIV-negative subjects.

24 Jun 2014

New model for HIV-1 infection offers promising option for clinical research

HIV-1, the virus responsible for most cases of AIDS, is a very selective virus. It does not readily infect species other than its usual hosts — humans and chimpanzees.

20 Jun 2014

La Jolla Institute researchers advance work toward vaccine for heart disease

Research toward the world's first vaccine for heart disease continues to advance at the La Jolla Institute for Allergy and Immunology, with researchers demonstrating significant arterial plaque reduction in concept testing in mice.

18 Jun 2014

Mechanisms of recurrent bacteria AOM in children under scrutiny

The immune response in young children with bacterial acute otitis media differs between individuals who are prone to such infection and those who are not, US researchers have shown.

16 Jun 2014

Inovio evaluates responses of immunotherapy product in treating HPV linked head and neck cancer

Inovio Pharmaceuticals, Inc. (NYSE MKT: INO) today announced it has initiated a phase I/IIa clinical trial to evaluate safety, immunogenicity and clinical responses of its immunotherapy product, INO-3112, in treating human papillomavirus (HPV)- associated head and neck cancer.

10 Jun 2014

Wistar findings suggest means of boosting initial immune response

Your first response to an infectious agent or antigen ordinarily takes about a week, and is relatively weak. However, if your immune system encounters that antigen a second time, the so-called memory response is rapid, powerful, and very effective.

10 Jun 2014

HCV reactivation may not worsen survival outcomes for lymphoma patients with HIV

More than a quarter of HIV+ patients are also infected with the Hepatitis C virus (HCV), which may complicate treatment and care decisions after a cancer diagnosis. The specifics of those complications haven't been well-researched in the past. Results from a new Fox Chase Cancer Center study on this patient population may start filling in that gap.

31 May 2014

CIRM grants $5.6 million to develop HIV/AIDS therapeutic using Sangamo's ZFN genome-editing technology

Sangamo BioSciences, Inc. announced that the California Institute for Regenerative Medicine (CIRM) has granted a $5.6 million Strategic Partnership Award to fund clinical studies at City of Hope to develop a potentially curative ZFP Therapeutic for HIV/AIDS based on the application of Sangamo's zinc finger nuclease (ZFN) genome-editing technology in hematopoietic stem/progenitor cells (HSPCs).

31 May 2014

Patients with AIDS-related lymphomas may face increased risk of CNSi

Patients with AIDS-related lymphomas (ARL) may face an increased risk of central nervous system involvement (CNSi) compared to other lymphomas. The effect of CNSi on survival outcomes, however, hasn't been thoroughly examined until now.

31 May 2014

TSRI scientists receive more than $13M to design effective HIV vaccine

A team led by scientists at The Scripps Research Institute (TSRI) has received a grant of more than $13 million from the National Institute of Allergy and Infectious Disease of the National Institutes of Health to study antibodies to the human immunodeficiency virus (HIV)—which will play an essential role in the creation of any effective vaccine against HIV.

30 May 2014

TSRI scientists receive $13M grant to create effective vaccine against HIV

A team led by scientists at The Scripps Research Institute (TSRI) has received a grant of more than $13 million from the National Institute of Allergy and Infectious Disease of the National Institutes of Health to study antibodies to the human immunodeficiency virus (HIV)-which will play an essential role in the creation of any effective vaccine against HIV.

30 May 2014

CD4 News and Research

MSD announces Phase 2b results of doravirine therapy in untreated patients with HIV-1 infection

New research sheds light on future efforts to eradicate HIV from the body in human patients

Daktari receives NIH SBIR grant to develop point-of-care sickle cell diagnostic test

New breast cancer vaccine provides evidence of immunotherapy in preventing disease recurrence

New blood test provides fast, accurate diagnosis of tuberculosis in children

Pilot study shows that anti-cancer drug can activate hidden HIV

HIV detected in Mississippi baby after apparent cure

Mississippi baby: Infant seemingly cured of HIV has detectable levels of HIV

GSMA announces mobile ecosystem partnership to provide mHealth services to women, children

Study finds link between high CD4 cell counts and reduced ischemic stroke risk in people with HIV

New model for HIV-1 infection offers promising option for clinical research

La Jolla Institute researchers advance work toward vaccine for heart disease

Mechanisms of recurrent bacteria AOM in children under scrutiny

Inovio evaluates responses of immunotherapy product in treating HPV linked head and neck cancer

Wistar findings suggest means of boosting initial immune response

HCV reactivation may not worsen survival outcomes for lymphoma patients with HIV

CIRM grants $5.6 million to develop HIV/AIDS therapeutic using Sangamo's ZFN genome-editing technology

Patients with AIDS-related lymphomas may face increased risk of CNSi

TSRI scientists receive more than $13M to design effective HIV vaccine

TSRI scientists receive $13M grant to create effective vaccine against HIV

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

Latest News