Fracture News and Research

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Hospitalization for an acute event can lead to long-term institutionalization

Confirming many elderly patients' worst fears, a national study has shown that being hospitalized for an acute event, such as a stroke or hip fracture, can lead to long-term institutionalization in a nursing home. Equally alarming, researchers found that direct discharge to a skilled nursing facility -- a common practice designed to reduce hospital stays -- put patients at "extremely high risk" of needing long-term nursing home care.

4 Oct 2011

$Hip fracture may increase short-term mortality for women ages 65 to 79 years$

Hip fracture may increase short-term mortality for women ages 65 to 79 years

Hip fracture is associated with an increase in short-term mortality (death within one year) for women ages 65 to 79 years and healthy women ages 80 years and older, although the risk returns to previous levels after one year for women ages 70 years and older, according to a report published Online First by Archives of Internal Medicine, one of the JAMA/Archives journals.

27 Sep 2011

$Women ages 65-69 with hip fracture more likely to die within a year$

Women ages 65-69 with hip fracture more likely to die within a year

Women ages 65-69 who break a hip are five times more likely to die within a year than women of the same age who don't break a hip, according to a Kaiser Permanente Center for Health Research study funded by the National Institutes of Health and published online today in the Archives of Internal Medicine.

27 Sep 2011

Ibandronate controls pain in prostate cancer patients with bone metastases

Many prostate cancer patients develop bone metastases, and controlling the pain these cause can be difficult. Now the first large randomised Phase III trial of a bisphosphonate drug in these patients has shown that a single dose of the drug is as good for pain relief as single dose radiotherapy, the standard treatment for bone metastases. Results of the trial were presented at the 2011 European Multidisciplinary Cancer Congress.

26 Sep 2011

Gamma radiation could toughen up plastic prosthetic joints

A blast of gamma radiation could toughen up plastic prosthetic joints to make them strong enough to last for years, according to researchers in China writing in the current issue of the International Journal of Biomedical Engineering and Technology.

23 Sep 2011

Amgen's Prolia receives FDA approval for new indications to treat cancer patients

Amgen today announced that the U.S. Food and Drug Administration (FDA) approved two new indications for Prolia® (denosumab) as a treatment to increase bone mass in women at high risk for fracture receiving adjuvant aromatase inhibitor therapy for breast cancer and as a treatment to increase bone mass in men at high risk for fracture receiving androgen deprivation therapy for non-metastatic prostate cancer.

19 Sep 2011

Tarsa reports positive data from OSTORA Phase III ORACAL trial for postmenopausal osteoporosis

Tarsa Therapeutics today reported that it presented positive safety and efficacy data from its Phase III ORACAL trial of OSTORA, the company's oral recombinant salmon calcitonin tablet in development for the treatment of postmenopausal osteoporosis.

19 Sep 2011

Positive data from Tarsa's OSTORA Phase III trial on postmenopausal osteoporosis

Tarsa Therapeutics today presented positive safety and efficacy data from its Phase III ORACAL trial of OSTORA-, the company's oral recombinant salmon calcitonin tablet in development for the treatment of postmenopausal osteoporosis.

19 Sep 2011

FDA advisory panel suggests warning for bisphosphonates but does not specify wording

Two independent advisory panels to the Food and Drug Administration (FDA) on Friday recommended increasing the cautionary language on the product labels of bone-building drugs taken by more than five million women in the United States. They did not however mention the exact words of the safety warnings and did not recommend limiting use of the drugs to a proposed five years. About 11 percent of women 55 and older take the drugs to prevent bone fractures.

12 Sep 2011

AOI Medical receives ISO 13485 Certification and CE marking approval for two VCF devices

AOI Medical, Inc. has received ISO 13485 Certification and CE marking approval for its Ascendx VCF Repair System and its Ascendx Acu-Cut Vertebral Augmentation System to treat vertebral compression fractures (VCF).

8 Sep 2011

IOF presents eight young investigator awards to researchers across the world

Eight IOF Young Investigator Awards were presented by the International Osteoporosis Foundation (IOF) to young researchers from Australia, China, India and Japan, in recognition of their outstanding work. The awards, valued at 1,000 USD each, were awarded to the highest scored abstracts by researchers under the age of 40.

7 Sep 2011

Kettering University's biodegradable magnesium alloy can repair traumatic bone injury

Repairing traumatic injury to a bone is possible, but current procedures require multiple surgeries and long-term recovery. Kettering University's Dr. Montserrat Rabago-Smith and her team of co-researchers are exploring the use of a magnesium orthotic alloy in severe trauma injuries where the distance between two halves of a bone can't be overcome by the human body's ability to regenerate and heal.

26 Aug 2011

Research roundup: Majority of Docs face malpractice claims; colonoscopies in older adults; 'overwhelming' Medicare advantage choices

The authors "analyzed malpractice data from 1991 through 2005 for all physicians who were covered by a large professional liability insurer with a nationwide client base" and found that "by the age of 65 years, 75% of physicians in low-risk specialties had faced a malpractice claim, as compared with 99% of physicians in high-risk specialties." Most of those claims did not result in a pyament.

20 Aug 2011

Amgen to present data from several Prolia studies at ASBMR 2011 meeting

Amgen today announced that it will present data from several Prolia (denosumab) studies, including eight year efficacy and safety data from a Phase 2 extension study in women with postmenopausal osteoporosis with low bone mineral density (BMD), at the 2011 American Society for Bone and Mineral Research (ASBMR) Annual Meeting in San Diego, Calif. from Sept. 16-20, 2011.

19 Aug 2011

$Dried plums can protect postmenopausal women against fractures, osteoporosis$

Dried plums can protect postmenopausal women against fractures, osteoporosis

When it comes to improving bone health in postmenopausal women — and people of all ages, actually — a Florida State University researcher has found a simple, proactive solution to help prevent fractures and osteoporosis: eating dried plums.

19 Aug 2011

IU scientist to investigate salubrinal drug against osteoporosis

An Indiana University scientist studying human bone growth has received a $2.6 million grant from the U.S. Department of Defense to study a chemical compound with potential to fight osteoporosis and accelerate broken bone healing.

18 Aug 2011

AHRQ's new Spanish-language guide on heart medications

A free, illustrated easy-to-read pamphlet that compares drugs for preventing heart attacks, heart failure or strokes in people with stable coronary heart disease is one of six new Spanish-language publications from HHS' Agency for Healthcare Research and Quality that help patients compare treatments for common illnesses.

16 Aug 2011

Neurologist care may improve quality of life for people with Parkinson's

People with Parkinson's disease who go to a neurologist for their care are more likely to live longer, less likely to be placed in a nursing home and less likely to break a hip than people who go to a primary care physician, according to a study published in the August 10, 2011, online issue of Neurology, the medical journal of the American Academy of Neurology.

11 Aug 2011

Current Medical Research & Opinion publishes new data on EVISTA for postmenopausal osteoporosis

Eli Lilly and Company today announced that data on EVISTA® (raloxifene HCl tablets) therapy for more than three years was published online in Current Medical Research & Opinion.

10 Aug 2011

Unigene second quarter revenue decreases to $2.5 million

Unigene Laboratories, Inc. a leader in the design, delivery, manufacture and development of peptide-based therapeutics announced second quarter financial results for the period ended June 30, 2011. The Company highlighted significant progress achieved in the second quarter with the continued execution of its turnaround strategy.

8 Aug 2011

Fracture News and Research

Hospitalization for an acute event can lead to long-term institutionalization

Hip fracture may increase short-term mortality for women ages 65 to 79 years

Women ages 65-69 with hip fracture more likely to die within a year

Ibandronate controls pain in prostate cancer patients with bone metastases

Gamma radiation could toughen up plastic prosthetic joints

Amgen's Prolia receives FDA approval for new indications to treat cancer patients

Tarsa reports positive data from OSTORA Phase III ORACAL trial for postmenopausal osteoporosis

Positive data from Tarsa's OSTORA Phase III trial on postmenopausal osteoporosis

FDA advisory panel suggests warning for bisphosphonates but does not specify wording

AOI Medical receives ISO 13485 Certification and CE marking approval for two VCF devices

IOF presents eight young investigator awards to researchers across the world

Kettering University's biodegradable magnesium alloy can repair traumatic bone injury

Research roundup: Majority of Docs face malpractice claims; colonoscopies in older adults; 'overwhelming' Medicare advantage choices

Amgen to present data from several Prolia studies at ASBMR 2011 meeting

Dried plums can protect postmenopausal women against fractures, osteoporosis

IU scientist to investigate salubrinal drug against osteoporosis

AHRQ's new Spanish-language guide on heart medications

Neurologist care may improve quality of life for people with Parkinson's

Current Medical Research & Opinion publishes new data on EVISTA for postmenopausal osteoporosis

Unigene second quarter revenue decreases to $2.5 million

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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