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Scientific breakthrough could contribute to early diagnosis of osteoporosis, Alzheimer's

Scientists from the University of Granada have developed a new fluorescent dye capable of detecting, in a single test lasting 20 minutes, the presence of phosphate and biothiol inside living cells. This scientific breakthrough could contribute significantly to the early diagnosis of diseases such as osteoporosis, Alzheimer's, type 2 diabetes, and prostate cancer, since abnormal levels of both substances are associated with these diseases.

30 Jan 2016

TSRI scientists reveal workings of key 'relief-valve' in cells

A team led by scientists at The Scripps Research Institute has solved a long-standing mystery in cell biology by showing essentially how a key "relief-valve" in cells does its job.

30 Jan 2016

Researchers explore ways to use light to combat cancer

Immunotherapy is one of the hottest emerging areas of cancer research. After all, using the body's own cells to fight cancer can be more effective and less invasive than flooding the entire system with toxic chemicals.

22 Jan 2016

New clinical chemistry analyzer highlighted by EKF Diagnostics at Arab Health 2016

EKF, will be highlighting its new Altair 240 clinical chemistry analyzer alongside many of its other POC and lab diagnostics products.

From EKF Diagnostics 21 Jan 2016

Upsher-Smith, Saniona sign drug discovery and development agreement

Upsher-Smith Laboratories, Inc., through its wholly-owned subsidiary Proximagen Ltd., and Saniona, a leading biotech company in the field of ion channels, today announce that they have entered into a drug discovery and development collaboration.

20 Jan 2016

Researchers reconstruct 3D images of protein structures that link heart muscle cells in working groups

Diseased hearts may be thrown out of rhythm by structural differences -- now visible for the first time -- in protein groups that connect heart muscle cells, according to the authors of a study to be published in the journal Nature Communications online Jan. 20.

20 Jan 2016

Amorphous iron nanoparticles have potential to kill tumor cells

Amorphous iron nanoparticles have a specific toxicity in tumor cells. In the journal Angewandte Chemie, Chinese scientists describe their design and synthesis of a special amorphous state of nanoparticulate iron, which can locally release reactive iron species in the acidic and hydrogen peroxide rich environment of cancer cells, providing new possibilities for theranostics and chemodynamic therapies.

20 Jan 2016

New study sheds light on possible role of ion channel in the immune system

Many cells have microscopic gates, called ion channels, which open to allow the flow of ions across the cell membrane. Thanks to these gates, cells can detect stimuli such as heat, pain, pressure and even spicy food.

20 Jan 2016

MEDPRO project develops realistic model of future health care system

What will our health care system look like in the future? The MEDPRO project of the Austrian Science Fund FWF seeks to deliver answers to this pertinent question.

20 Jan 2016

Researchers identify protein structure linked to pain and heat perception

Touch a hot stove, and your fingers will recoil in pain because your skin carries tiny temperature sensors that detect heat and send a message to your brain saying, "Ouch! That's hot! Let go!"

19 Jan 2016

NIST researchers simulate new method for fast, precise DNA sequencing

Researchers at the National Institute of Standards and Technology (NIST) have simulated a new concept for rapid, accurate gene sequencing by pulling a DNA molecule through a tiny, chemically activated hole in graphene--an ultrathin sheet of carbon atoms--and detecting changes in electrical current.

19 Jan 2016

Findings offer potential new therapeutic target to boost strength of heart muscle contractions

Researchers at UT Southwestern Medical Center have identified a previously unrecognized small protein in cells of the human heart that plays a key role in heart muscle contraction. The protein is made from an RNA that was previously believed to be a blank or non-coding RNA, suggesting there may be many other small 'non-coding' segments that play important biological roles.

18 Jan 2016

FDA grants Orphan Drug Designation to Ionis Pharmaceuticals' IONIS-HTT Rx for treatment of HD patients

Ionis Pharmaceuticals, Inc. today announced that the U.S. Food and Drug Administration has granted Orphan Drug Designation to IONIS-HTTRx for the treatment of patients with Huntington's disease (HD).

5 Jan 2016

Ardelyx announces positive results from RDX022 clinical study for treatment of hyperkalemia

Ardelyx, Inc., a clinical-stage biopharmaceutical company focused on gastrointestinal and cardio-renal diseases, today announced positive results of an open label clinical study evaluating the pharmacodynamic (PD) activity of RDX022 in healthy adult volunteers.

5 Jan 2016

New guide provides valuable, unique overview of key properties of different drug targets

The new Concise Guide to PHARMACOLOGY 2015/2016 provides a valuable and unique overview of the key properties of more than 1,700 human drug targets, focusing on those exploited currently in the clinic or with future therapeutic potential.

5 Jan 2016

Delivering novel formulation of propranolol as liquid salt may reduce skin toxicity

Formulating drugs as liquid salts may provide a safe and efficient strategy for topical delivery of drugs that cause skin toxicity. A team of researchers from the University of California, Santa Barbara (UCSB) in Santa Barbara, CA has demonstrated a novel formulation of propranolol as a liquid salt which enables delivery through skin with reduced toxicity.

30 Dec 2015

Bioactive glass may help prolong life of composite tooth fillings

A few years from now millions of people around the world might be walking around with an unusual kind of glass in their mouth, and using it every time they eat.

23 Dec 2015

Researchers describe epigenetic mechanisms underlying the development of cerebellum

From before birth through childhood, connections form between neurons in the brain, ultimately making us who we are. So far, scientists have gained a relatively good understanding of how neural circuits become established, but they know less about the genetic control at play during this crucial developmental process.

23 Dec 2015

New test can help detect cancer and diabetes biomarkers in bloodstream

A new test for detecting biomarkers for cancer and diabetes is more than 1000x more detailed and 100% faster than existing methods, new research by the University of Warwick suggests.

18 Dec 2015

New study finds a reason for ethnic disparity in CF diagnoses

Cystic fibrosis (CF) occurs less frequently in nonwhites than in whites, and nonwhites tend to be diagnosed at a later age. This late diagnosis often comes only once they have become symptomatic, rather than through newborn screening programs or molecular diagnostic testing.

16 Dec 2015

Ion News and Research

Scientific breakthrough could contribute to early diagnosis of osteoporosis, Alzheimer's

TSRI scientists reveal workings of key 'relief-valve' in cells

Researchers explore ways to use light to combat cancer

New clinical chemistry analyzer highlighted by EKF Diagnostics at Arab Health 2016

Upsher-Smith, Saniona sign drug discovery and development agreement

Researchers reconstruct 3D images of protein structures that link heart muscle cells in working groups

Amorphous iron nanoparticles have potential to kill tumor cells

New study sheds light on possible role of ion channel in the immune system

MEDPRO project develops realistic model of future health care system

Researchers identify protein structure linked to pain and heat perception

NIST researchers simulate new method for fast, precise DNA sequencing

Findings offer potential new therapeutic target to boost strength of heart muscle contractions

FDA grants Orphan Drug Designation to Ionis Pharmaceuticals' IONIS-HTT Rx for treatment of HD patients

Ardelyx announces positive results from RDX022 clinical study for treatment of hyperkalemia

New guide provides valuable, unique overview of key properties of different drug targets

Delivering novel formulation of propranolol as liquid salt may reduce skin toxicity

Bioactive glass may help prolong life of composite tooth fillings

Researchers describe epigenetic mechanisms underlying the development of cerebellum

New test can help detect cancer and diabetes biomarkers in bloodstream

New study finds a reason for ethnic disparity in CF diagnoses

Enhancing confidence in chemical ionization spectrometry data eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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