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Teen-LABS research study reveals musculoskeletal disease outcomes among obese adolescents

Outcomes regarding musculoskeletal disease among severely obese adolescents participating in the "Teen Longitudinal Assessment of Bariatric Surgery" (Teen-LABS) study were published this week in JAMA Pediatrics. Teen-LABS is a multi-center clinical study funded by the National Institute of Diabetes and Digestive and Kidney Diseases at the National Institutes of Health that is examining the safety and health effects of surgical weight loss procedures.

28 Apr 2015

First FDA-approved modular system for infected total joints

OsteoRemedies®, LLC, Memphis, TN, offers the first FDA-approved modular system for two-stage revision of infected hip and knee arthroplasty.

26 Apr 2015

Epigenetic processes influence children's later ability to learn and cognitive performance

Although it is now widely recognised that a poor start to life has long-term effects on a child's later ability to learn, the mechanisms by which the environment in early life affects later life chances are poorly understood.

23 Apr 2015

Ibrutinib (IMBRUVICA) may be effective for pancreatic ductal adenocarcinoma

Ibrutinib (IMBRUVICA) data presented yesterday by Pharmacyclics, Inc. at the American Association for Cancer Research Annual Meeting suggest that ibrutinib may be an effective therapeutic option for pancreatic ductal adenocarcinoma (PDAC), as shown in both a transgenic mouse model and an in-vivo model of patient-derived xenograft (PDX) mice (grafts of tissue taken from a pancreatic cancer patient and grafted into a mouse).

20 Apr 2015

Osteocyte study in space: Researchers to analyze effects of microgravity on osteocyte cultures

Researchers may be "excyted" to learn that osteocyte cultures are headed to the International Space Station this spring for the first time. With their delivery on the next SpaceX commercial resupply services mission this month, the Osteocytes and mechano-transduction (Osteo-4) investigation team will analyze the effects of microgravity on this type of bone cell.

13 Apr 2015

Pharmacyclics announces positive results from IMBRUVICA Phase II study in WM patients

Pharmacyclics, Inc. today announced longer-term data from a Phase II investigator-initiated study showing Waldenstrom's macroglobulinemia (WM) patients treated with IMBRUVICA (ibrutinib) experienced sustained disease control with an overall response rate (ORR) of 91% after a median of 19.1 months of treatment and a 2-year overall survival (OS) rate of 95%.

9 Apr 2015

$Incidence, costs of osteoporotic fractures in China to double by 2035$

Incidence, costs of osteoporotic fractures in China to double by 2035

The results of the first study using a health economics model to project osteoporosis-related fractures and costs for the Chinese population, shows that the country's healthcare system will face a dramatic rise in costs over the next few decades.

8 Apr 2015

Deep brain stimulation reduces PD pain severity but does not prevent it

Subthalamic nucleus deep brain stimulation has a beneficial effect on pain severity in patients with Parkinson’s disease that persists for up to 8 years, say researchers, but new onset of musculoskeletal pain in many suggests its effects are not enduring.

7 Apr 2015

Scientists identify small RNA molecule that can suppress cancer-causing genes in GBM

Northwestern Medicine scientists have identified a small RNA molecule called miR-182 that can suppress cancer-causing genes in mice with glioblastoma mulitforme (GBM), a deadly and incurable type of brain tumor.

6 Apr 2015

Astellas Pharma, Medivation announce topline results from enzalutamide Phase 2 STRIVE trial

Astellas Pharma Inc. and Medivation, Inc. today announced topline results from the Phase 2 STRIVE trial comparing enzalutamide with bicalutamide in a study population of men with non-metastatic or metastatic castration-resistant prostate cancer.

2 Apr 2015

BME announces launch of Speed Titan Nitinol Bone Fixation Implant

BioMedical Enterprises announced the launch of the Speed Titan Nitinol Bone Fixation Implant today. As the newest addition to the BME Speed Fixation System, the Speed Titan joins the BME Speed, Speed Arc and Speed Shift™ implants to create the world's most comprehensive family of continuous active compression Nitinol implants.

1 Apr 2015

$FLS could reduce healthcare costs associated with osteoporotic fractures$

FLS could reduce healthcare costs associated with osteoporotic fractures

Using a simulation model, Swedish researchers have shown that the implementation of Fracture Liaison Services (FLS) could considerably reduce the human and healthcare costs associated with osteoporotic fractures. The results from the model were presented today at the World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases in Milan.

30 Mar 2015

Study demonstrates abnormal vitamin D levels in more than one-third of elite NCAA Division I athletes

A new study presented today at the 2015 Annual Meeting of the American Academy of Orthopaedic Surgeons found that more than one-third of elite, Division I college athletes may have low levels of vitamin D, which is critical in helping the body to absorb calcium needed to maintain bone mass, and to minimize musculoskeletal pain and injury risk.

30 Mar 2015

$New study estimates UK hospital costs of hip fracture$

New study estimates UK hospital costs of hip fracture

A new study presented today at the World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases reveals the high cost of first and subsequent hip fractures to the healthcare system in the UK.

30 Mar 2015

Top experts focus on musculoskeletal disorders in open key Congress in Milan

Musculoskeletal conditions, which affect over 1.7 billion people worldwide, will be the focus of a major four-day Congress which opens today in Milan, Italy.

30 Mar 2015

Bariatric surgery prior to joint replacement improves outcomes in obese patients

Obesity is not only a risk factor for developing knee and hip arthritis. It is also linked to less favorable outcomes after joint replacement surgery.

30 Mar 2015

Arthritis & Osteoporosis NSW to hold Clinical Update for 2015 for health professionals

Arthritis is a condition that affects over 1.1 million people in NSW and over 3 million people across Australia and with an ageing population, that figure is projected to reach 7 million by 2050. Arthritis is a condition which affects people across all ages, backgrounds, men and women alike.

27 Mar 2015

DePuy Synthes adds four new products to adult deformity portfolio

DePuy Synthes Companies announced the addition of four new products to its adult deformity portfolio as well as a new education offering, continuing its expansion of one of the broadest spine portfolios in the industry. The products were displayed by DePuy Synthes Spine at the 81st annual meeting of the American Academy of Orthopaedic Surgeons.

27 Mar 2015

$HSS study examines racial and socioeconomic disparities in hip fracture care$

HSS study examines racial and socioeconomic disparities in hip fracture care

A study by researchers at Hospital for Special Surgery (HSS) finds that people in certain racial and socioeconomic groups are at a disadvantage when it comes to care they receive after fracturing a hip.

25 Mar 2015

Hip replacement procedure alleviates pain, improves function in young JIA patients

Hip replacement is often performed in patients with juvenile arthritis when their joints have been severely damaged by the disease.

25 Mar 2015

Musculoskeletal News and Research

Teen-LABS research study reveals musculoskeletal disease outcomes among obese adolescents

First FDA-approved modular system for infected total joints

Epigenetic processes influence children's later ability to learn and cognitive performance

Ibrutinib (IMBRUVICA) may be effective for pancreatic ductal adenocarcinoma

Osteocyte study in space: Researchers to analyze effects of microgravity on osteocyte cultures

Pharmacyclics announces positive results from IMBRUVICA Phase II study in WM patients

Incidence, costs of osteoporotic fractures in China to double by 2035

Deep brain stimulation reduces PD pain severity but does not prevent it

Scientists identify small RNA molecule that can suppress cancer-causing genes in GBM

Astellas Pharma, Medivation announce topline results from enzalutamide Phase 2 STRIVE trial

BME announces launch of Speed Titan Nitinol Bone Fixation Implant

FLS could reduce healthcare costs associated with osteoporotic fractures

Study demonstrates abnormal vitamin D levels in more than one-third of elite NCAA Division I athletes

New study estimates UK hospital costs of hip fracture

Top experts focus on musculoskeletal disorders in open key Congress in Milan

Bariatric surgery prior to joint replacement improves outcomes in obese patients

Arthritis & Osteoporosis NSW to hold Clinical Update for 2015 for health professionals

DePuy Synthes adds four new products to adult deformity portfolio

HSS study examines racial and socioeconomic disparities in hip fracture care

Hip replacement procedure alleviates pain, improves function in young JIA patients

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