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Antigenic differences between early SARS-CoV-2 variants

Researchers used antigenic cartography to quantify and visualize antigenic differences between multiple SARS‐CoV‐2 variants.

27 Jun 2022

Does fecal viral excretion provide insights into on GI symptoms of COVID-19?

Researchers discuss the physiopathological mechanisms associated with digestive symptoms associated with COVID-19.

27 Jun 2022

Associations between maternal COVID-19 vaccination and hospitalization among infants

Researchers assessed the efficacy of maternal mRNA vaccinations during pregnancy against hospitalization for COVID-19 in infants aged <6 months.

24 Jun 2022

Overlap in pro-inflammatory genes and pathways between COVID-19 and MIS-C

In a recent study posted to the medRxiv* pre-print server, researchers in the United States characterized differential host immune responses in acute coronavirus disease 2019 (COVID-19) and multisystem inflammatory syndrome in children (MIS-C) to inform future development of novel biomarkers for both diseases.

23 Jun 2022

Mutation in SARS-CoV-2 nucleocapsid protein found to enhance replication and pathogenicity

Researchers investigated a highly variable region at residues 203 to 205 in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nucleocapsid (N) protein.

23 Jun 2022

Correlates of anamnestic humoral immunity throughout SARS-CoV-2 variants of concern

A recent work posted to the bioRxiv* preprint server assessed the indicators of anamnestic humoral immunity among the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs).

23 Jun 2022

Analyzing biophysical restrictions of SARS-CoV-2 N-terminal domain

In a recent article posted to the bioRxiv* preprint server, researchers at the University of Illinois at Urbana-Champaign, Scripps Research Institute, and Case Western Reserve University evaluated the biophysical limitations of the spike (S) N-terminal domain (NTD) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

23 Jun 2022

The possible immune-mediated mechanisms causing CNS alterations during and post-acute SARS-CoV-2 infection

In a recent review published in Immunity, researchers explored potential mechanisms of neuro-immune pathophysiology of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections.

22 Jun 2022

Gene expression regulation by N6-methyladenosine

A recent study published in Molecular Cell reviewed the control of gene expression by N6-methyladenosine (m6A), a modified nucleotide in the messenger ribonucleic acid (mRNA).

22 Jun 2022

Researchers map cancer driver mutations across the human genome

In a recent study published in Nature Biotechnology, researchers explored the causes of cancer by mapping somatic mutation rates across the human genome.

22 Jun 2022

Even asymptomatic maternal COVID-19 can potentially cause pregnancy complications

A recent study published in the Cell Reports journal analyzed immune ecology at the placenta in mild or asymptomatic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection during pregnancy.

22 Jun 2022

A longitudinal population-based study of COVID-19 in the UK

In a recent study posted to the medRxiv* pre-print server, researchers identified potential risk factors and incident symptoms of coronavirus disease 2019 (COVID-19) in the general population of the United Kingdom (UK).

21 Jun 2022

Researchers compare the development and persistence of antibody and T-cell responses elicited by the mRNA BNT162b2 vaccine or SARS-CoV-2 infection

Researchers comparatively assessed the generation of B lymphocyte-mediated antibody responses and T lymphocyte-mediated cellular responses between mRNA BNT162b vaccinees and mild COVID-19 patients.

21 Jun 2022

An estimate of Omicron's fitness advantage

Researchers quantify the transmission advantage of the SARS-CoV-2 Omicron variant across forty countries.

21 Jun 2022

Scientists explore brainstem circuits to find nausea intervention strategies

In a new study, researchers uncovered the organization of nausea-associated brainstem circuits to show that selectively blocking the excitatory neurons responsive to nausea-promoting growth/differentiation factor 15 suppresses nausea-related behaviors.

20 Jun 2022

Model predicts effectiveness of COVID-19 vaccines against circulating SARS-CoV-2 variants

In a recent study published in the journal Nature Medicine, researchers assessed the coronavirus disease 2019 (COVID-19) vaccine effectiveness (VE) against symptomatic infections with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) and variants of interest (VOIs) by genetic mismatch/distance (GD) analysis.

20 Jun 2022

How effective are mRNA COVID-19 vaccine boosters against Omicron?

In a recent study posted to the medRxiv* preprint server, researchers University of Washington, University of Michigan, Duke University, and Veterans Affairs Portland Healthcare System assessed the effectiveness of the coronavirus disease 2019 (COVID-19) booster vaccines.

19 Jun 2022

Effectiveness of previous COVID-19 and vaccination against SARS-CoV-2 Omicron infection

Researchers studied the effects of prior immunity on symptomatic infection by SARS-CoV-2 Omicron.

17 Jun 2022

SARS-CoV-2 variant-specific polymerase chain reaction assay for SARS-CoV-2 genomic surveillance

Researchers reported on the misclassification of the SARS-CoV-2 Omicron BA.1 subvariant as Omicron BA.2 subvariant in an automated variant-specific polymerase chain reaction analysis.

17 Jun 2022

Demonstrating varying pathogenicity and tropism of SARS-CoV-2 variants in a feline model

In a recent study posted to the bioRxiv* pre-print server, researchers at Cornell University College of Veterinary Medicine and the University of Illinois Urbana-Champaign compared the infection dynamics, pathogenicity, and tissue tropism of multiple severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants in adult cats.

17 Jun 2022

Ribonucleic Acid News and Research

Antigenic differences between early SARS-CoV-2 variants

Does fecal viral excretion provide insights into on GI symptoms of COVID-19?

Associations between maternal COVID-19 vaccination and hospitalization among infants

Overlap in pro-inflammatory genes and pathways between COVID-19 and MIS-C

Mutation in SARS-CoV-2 nucleocapsid protein found to enhance replication and pathogenicity

Correlates of anamnestic humoral immunity throughout SARS-CoV-2 variants of concern

Analyzing biophysical restrictions of SARS-CoV-2 N-terminal domain

The possible immune-mediated mechanisms causing CNS alterations during and post-acute SARS-CoV-2 infection

Gene expression regulation by N6-methyladenosine

Researchers map cancer driver mutations across the human genome

Even asymptomatic maternal COVID-19 can potentially cause pregnancy complications

A longitudinal population-based study of COVID-19 in the UK

Researchers compare the development and persistence of antibody and T-cell responses elicited by the mRNA BNT162b2 vaccine or SARS-CoV-2 infection

An estimate of Omicron's fitness advantage

Scientists explore brainstem circuits to find nausea intervention strategies

Model predicts effectiveness of COVID-19 vaccines against circulating SARS-CoV-2 variants

How effective are mRNA COVID-19 vaccine boosters against Omicron?

Effectiveness of previous COVID-19 and vaccination against SARS-CoV-2 Omicron infection

SARS-CoV-2 variant-specific polymerase chain reaction assay for SARS-CoV-2 genomic surveillance

Demonstrating varying pathogenicity and tropism of SARS-CoV-2 variants in a feline model

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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