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Fritz Lipmann Institute receives 2.5 million euros to advance microbiome research

Fungi, bacteria, archaea and viruses - trillions of microorganisms colonize the skin, mucous membranes and organs of humans. Together, they constitute the microbiome.

3 Feb 2022

CRISPRa method helps discover genes that play a role in immune cell biology

CRISPR genome editing has served as a powerful tool for deleting or altering DNA sequences and studying the resulting effect.

3 Feb 2022

Innate and adaptive immune responses to SARS-CoV-2 in convalescent children and adults

In a new study, researchers explored the systemic immune responses during the acute and convalescent phases of SARS-CoV-2 in children and adults with the same disease severity.

3 Feb 2022

Relationship between SARS-CoV-2 neurotropism and Alzheimer's disease

In a new study, researchers evaluated the neurotropism of SARS-CoV-2 and its impact on COVID-19 patients with and without neurological disorders like Alzheimer's disease.

3 Feb 2022

Study reveals peripheral blood biomarkers able to predict COVID-19 clinical outcomes in ICU admission

A new study involved the development of an immunological biomarker screen that upon ICU admission can predict the length of ICU stay or death.

3 Feb 2022

Exploring human milk oligosaccharides as a method of COVID-19 prevention

New research was conducted to ascertain whether antiviral and immunomodulatory activities of human milk oligosaccharides can be efficacious in the prevention and treatment against COVID-19.

3 Feb 2022

Study describes the first three days of SARS-CoV-2 infection in an ALI model of proximal airway epithelium

Researchers evaluated the initial three days of SARS-CoV-2 infection via scRNAseq dataset in humanized in vitro model.

3 Feb 2022

Booster dose of Covaxin vaccine candidate neutralizes Omicron and Delta variants

Researchers evaluate the neutralization potential of sera samples from subjects boosted with the Covaxin against the SARS-CoV-2 Omicron variant.

2 Feb 2022

Study offers unprecedented insight into the mechanism of action of topo VI enzyme

The function of an enzyme, critical to most forms of life, has been revealed.

2 Feb 2022

Researchers receive $2,664,522 NIH award to improve long-term functionality of vascular grafts

A graft can be a life-saving device for coronary heart disease, which remains the leading cause of death for both men and women in the United States. However, at small diameters - such as the coronary artery in the heart - long-term graft failure rates are often higher than 40 percent.

2 Feb 2022

Three different autism risk genes found to have similar effects on brain development

Autism spectrum disorder has been associated with hundreds of different genes, but how these distinct genetic mutations converge on a similar pathology in patients has remained a mystery.

2 Feb 2022

CECR2 gene inhibition prevents triple-negative breast cancer from metastasizing, study shows

A new study by researchers at Yale Cancer Center shows inhibition of the CECR2 gene prevents triple-negative breast cancer from advancing or metastasizing.

2 Feb 2022

Combined treatment strategy essential to minimize lung sequelae in COVID-19 patients

A combined treatment strategy targeting SARS-CoV-2 symptoms and severe lung tissue injury is essential to minimize lung sequelae- chronic complications resulting from COVID-19 infection, according to a review published this week in Clinical Microbiology Reviews, a journal of the American Society for Microbiology.

2 Feb 2022

Study discovers how long-term memory T cells are formed after SARS-CoV-2 exposure

Exposure to SARS-CoV-2 by infection or vaccination generates immune cells that provide long-term immunity. These long-lived memory T cells play a key role in preventing severe cases of Covid-19. Researchers at the University of Zurich have now discovered how these memory T cells form.

2 Feb 2022

Researchers elucidate first 3D structure of regulator protein complex

Proteins are indispensable components in living organisms. They are not only "building material" for the body – they also make molecular communication between cells possible, they are needed for nerve impulses to occur, and they control chemical reactions.

2 Feb 2022

'Genetic scissors' can give rise to unforeseen heritable mutations

CRISPR-Cas9, the "genetic scissors", creates new potential for curing diseases; but treatments must be reliable. In a new study, researchers have discovered that the method can give rise to unforeseen changes in DNA that can be inherited by the next generation.

2 Feb 2022

B Cell News and Research

Fritz Lipmann Institute receives 2.5 million euros to advance microbiome research

CRISPRa method helps discover genes that play a role in immune cell biology

Innate and adaptive immune responses to SARS-CoV-2 in convalescent children and adults

Relationship between SARS-CoV-2 neurotropism and Alzheimer's disease

Study reveals peripheral blood biomarkers able to predict COVID-19 clinical outcomes in ICU admission

Exploring human milk oligosaccharides as a method of COVID-19 prevention

Study describes the first three days of SARS-CoV-2 infection in an ALI model of proximal airway epithelium

Booster dose of Covaxin vaccine candidate neutralizes Omicron and Delta variants

Study offers unprecedented insight into the mechanism of action of topo VI enzyme

Researchers receive $2,664,522 NIH award to improve long-term functionality of vascular grafts

Three different autism risk genes found to have similar effects on brain development

CECR2 gene inhibition prevents triple-negative breast cancer from metastasizing, study shows

Combined treatment strategy essential to minimize lung sequelae in COVID-19 patients

Study discovers how long-term memory T cells are formed after SARS-CoV-2 exposure

Researchers elucidate first 3D structure of regulator protein complex

'Genetic scissors' can give rise to unforeseen heritable mutations

Researchers discover mechanism behind loss of smell in people with COVID-19

The ability of individuals to cross-recognize the Omicron spike protein following vaccination or prior infection

Assessing an intranasal lentiviral booster against COVID-19 variants

Representative structures of SARS-CoV-2 and development of therapeutic agents for targeting these proteins

Immunology eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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