Therapy News and Research

RSS

Study investigates combined effects of cancer therapy and inherited genetics

Scientists at St. Jude Children's Research Hospital are studying the combined effect of cancer treatments and inherited mutations in DNA-repair genes.

5 Jun 2020

UTEP researchers unlock potential of carbon quantum dots to combat neurological disorders

The contributions of researchers from The University of Texas at El Paso (UTEP) have yielded the first indication that carbon quantum dots, a class of nanoparticles, can be utilized to combat neurological disorders, according to a paper published in the journal Processes as part its special issue on protein biosynthesis and drug design and delivery.

5 Jun 2020

Kidney impairment significantly higher among hospitalized COVID-19 patients

Germany was not hit as hard by the SARS-CoV-2 pandemic as many other European countries. The reason for this is that the wave of infection reached Germany later, that the authorities were warned by the situation in Italy and Spain and at an early stage ordered a lockdown and conducted extensive testing.

5 Jun 2020

New guidance for healthcare providers caring for hospitalized COVID-19 patients with diabetes

The COVID-19 pandemic presents new challenges for clinicians caring for infected patients with diabetes, according to new guidance published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

5 Jun 2020

Sleep fragmentation associated with inflammation and atherosclerosis

Disrupted nightly sleep and clogged arteries tend to sneak up on us as we age. And while both disorders may seem unrelated, a new study from the University of California, Berkeley, helps explain why they are, in fact, pathologically intertwined.

5 Jun 2020

European database investigates COVID-19 outcomes in patients with kidney failure

Experience throughout the world, including in Europe, shows that advanced age is the most important risk factor for death in COVID-19: people aged over 70 years are over 10 times more likely to die compared to those aged below 50.

5 Jun 2020

Newer data confirms survival advantages, but also side effects for ribociclib in breast cancer

In 2017 and 2019, the German Institute for Quality and Efficiency in Health Care had already examined the advantages and disadvantages of ribociclib in combination with an aromatase inhibitor or fulvestrant in comparison with the appropriate comparator therapy in patients after menopause, with hormone receptor-positive, HER2-negative, locally advanced or metastatic breast cancer.

5 Jun 2020

Study shows how psychedelic drug psilocybin works in the brain

Perhaps no region of the brain is more fittingly named than the claustrum, taken from the Latin word for "hidden or shut away."

5 Jun 2020

High uric acid levels protect against lung function decline in women

Researchers at Kumamoto University in Japan have discovered that uric acid, an antioxidant, protects against declining lung function from age or lung disease, especially in women.

5 Jun 2020

Study offers a deeper understanding of T cell immunity in the elderly

A study by Monash Biomedicine Discovery Institute (BDI) expands the understanding of the molecular pathways that control T cell function and survival and how it relates to declining T cell immunity in the elderly.

5 Jun 2020

New digital tool to support mental health of MS patients developed with UK HCPs

Biogen Inc. today announced the launch of a free, new, digital self-help tool to help people living with multiple sclerosis (MS) navigate the emotional challenges of life with the disease. The tool, named ACT MySelf, was developed by Biogen in collaboration with people living with MS, the MS Trust, a team of MS specialist nurses and an MS clinical psychologist.

5 Jun 2020

Study: MafB protein may protect against renal failure

Focal segmental glomerulosclerosis (FSGS) is a common cause of steroid-resistant nephrotic syndrome, a type of kidney disease that is accompanied by massive urinary protein loss and that may progress to end-stage renal disease.

5 Jun 2020

Antiviral effects for COVID-19: Early is better

A new study by an international team of researchers and published on the preprint server medRxiv* in June 2020 describes the possible reasons for inconsistent or null findings in clinical studies of antiviral drugs to date. It proposes a new approach to decide the sample size in light of its findings.

5 Jun 2020

A learning health system for dentists

The largest study to date of electronic dental records delves into both previously inaccessible data and data from understudied populations with the ultimate goal of improving oral treatment outcomes.

5 Jun 2020

Study highlights increased consumption of opioids in patients with osteoarthritis

Fentanyl, tramadol or tilidine: New European figures show that even in Europe increasingly more people are taking opioids for pain connected with rheumatic and musculoskeletal diseases.

5 Jun 2020

Experts debate over future Parkinson’s disease trial involving growth factors

Growth factors such as glial cell line-derived neurotrophic factor (GDNF) were initially thought to be exciting new treatments for Parkinson's disease (PD), but trials have been disappointing.

5 Jun 2020

Trial results show efficacy of netakimab for treating moderate-to-severe plaque psoriasis

Netakimab is a humanized anti-interleukin 17A antibody approved for the treatment of moderate-to-severe plaque psoriasis.

5 Jun 2020

Assessing the integrity of remdesivir clinical trial during COVID-19 pandemic

As acknowledged in the first remdesivir double-blind placebo-controlled clinical trial addressing treatment for COVID-19 recently published in Lancet (Wang, et al., April 29, 2020), a statistician at Rutgers Cancer Institute of New Jersey was called on to guard the integrity of that trial.

4 Jun 2020

Current advances in nanoparticles and their role as anticancer drug-delivery vectors

Nanotechnology has contributed a great deal to the field of medical science. It has enabled researchers to design tools to deliver drugs to specific targets in a living organism.

4 Jun 2020

Alpaca-derived antiviral agent neutralizes SARS-CoV-2

Researchers at Karolinska University Hospital and the University of Cape Town have identified an antibody fragment that targets the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein and potently neutralizes the virus.

4 Jun 2020