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Study evaluates effects of unpaired 1 gene overexpression on lifespan in flies

Alexey Moskalev, Ph.D., Head of the Laboratory of Geroprotective and Radioprotective technologies, and co-authors from the Institute of biology of Komi Science Center of RAS announce the publication of a scientific article titled "Effects of unpaired 1 gene overexpression on the lifespan of Drosophila melanogaster" in BMC Systems Biology - an open access journal publishing original peer-reviewed research articles in experimental and theoretical aspects of the function of biological systems at the molecular, cellular or organismal level.

4 Apr 2019

New all-in-one immunotherapy approach kicks out hiding HIV and also kills it

In a first on the quest to cure HIV, University of Pittsburgh Graduate School of Public Health scientists report today in EBioMedicine that they've developed an all-in-one immunotherapy approach that not only kicks HIV out of hiding in the immune system, but also kills it.

4 Apr 2019

Mutation in Huntington’s disease may alter interactions of Huntingtin protein with Rac1

Since 1993, when the gene that causes Huntington's disease was identified, there has been intense focus on understanding how this genetic mutation causes the disease's severe progressive neural deterioration.

4 Apr 2019

Gene levels could be good indicator of prognosis in colorectal cancer patients

Levels of a gene that helps the immune system differentiate the good cells from the bad could be a good indicator of prognosis in people with colorectal cancers, Medical College of Georgia researchers report.

3 Apr 2019

Simplifying Gene Expression Analysis in Neuroscience Research

In this interview, Kevin Gamber introduces the Neuroscience panel of the NanoString service for gene expression analysis from Canopy Biosciences.

From Canopy Biosciences 3 Apr 2019

Salk researchers reveal new role for a driver of metastatic cancers

Metastatic ovarian, prostate and breast cancers are notoriously difficult to treat and often deadly. Now, Salk Institute researchers have revealed a new role for the CDK12 protein. The findings were published in the print version of Genes & Development on April 1, 2019.

3 Apr 2019

G:BOX Chemi XX6 imager used to speed up analysis of proteins linked with breast cancer

Syngene, a world-leading manufacturer of image analysis solutions, today announced its G:BOX Chemi XX6 multi-application imager is being utilized by scientists at a major London university to speed up analysis of proteins, DNA and cells associated with breast and a range of other cancer types.

From Syngene 3 Apr 2019

Postnova Analytics offers customer-friendly high performance MALS detector

The PN3621 Multi-Angle Light Scattering detector from Postnova Analytics combines outstanding performance, high precision and reliability design features to facilitate advanced characterization of proteins, conjugates, macromolecules, and nanoparticles.

From Postnova Analytics 3 Apr 2019

HCA Healthcare UK introduces ground-breaking new blood cancer treatment

HCA Healthcare UK has announced the launch of CAR T-cell therapy - a ground-breaking new blood cancer treatment which will be available to eligible patients with Diffuse Large B-Cell Lymphoma and Acute Lymphoblastic Leukaemia.

3 Apr 2019

Study explores how the brain finds meaning in metaphor

You can grasp a hand. You can also grasp a concept. One is literal. One is metaphorical. Our brains know the difference, but would we be able to understand the latter without the former?

3 Apr 2019

Photonics-based tiny device could one day play key role in personalized medicine

In the not-too-distant future, each of us may have a simple device - small enough for our nightstand or our pocket - that keeps us apprised of our level of health, identifies even trace amounts of undesirable biomarkers in our blood or saliva and serves as an early-warning system for diseases.

3 Apr 2019

Children born into poorer backgrounds show key differences in early brain function, finds study

Children born into poverty show key differences in early brain function - according to new research from the University of East Anglia.

2 Apr 2019

Researchers developing new tests for early detection, monitoring of lupus nephritis

With $5 million in grants from the National Institutes of Health, two University of Houston biomedical researchers are moving the needle on early detection and monitoring of kidney nephritis, or inflammation, in patients who have Systemic Lupus Erythematosus, known simply as lupus.

2 Apr 2019

Study reveals new strategy to combat antibiotic resistance

A new strategy to combat antibiotic resistance has emerged from a study led by researchers at Baylor College of Medicine. Published in the journal Molecular Cell, the report reveals for the first time how bacteria evolve mutations that confer antibiotic resistance and that this process can be inhibited with FDA-approved drug edaravone.

2 Apr 2019

New analysis establishes global microbial signatures for colorectal cancer

Cancers have long been known to arise due to environmental exposures such as unhealthy diet or smoking. Lately, the microbes living in and on our body have entered the stage as key players: while stomach cancer can be caused by a single bacterial species, Helicobacter pylori, the role that gut microbes play in the development of colorectal cancer - the third most common cancer worldwide - is less clear.

2 Apr 2019

Gut microbiota can help predict occurrence of colorectal cancer

Gut microbiota - the population of microbes that live in our intestine - can be used to predict the occurrence of colorectal cancer, the second most common type of cancer in women and the third in men.

1 Apr 2019

Single dose long lasting opioid antidote on the horizon

Recent reports have shown a 1,000 percent rise in opioid abuse (especially synthetic drug Fentanyl) in the United States over the past one decade. In 2017 for example there have been 47,000 deaths attributed to opioid overdose says the US Centre for Disease Control and Prevention (CDC).

31 Mar 2019

Hedgehogs connected to the outbreak of Salmonella

There has been a Salmonella outbreak across states in the United States and federal health officials have found that pet hedgehogs could be linked to some of these cases.

31 Mar 2019

ETH researchers take major step towards personalized cancer immunotherapy

Cells belonging to the body's own immune system can help fight tumours. For several years now, this has allowed oncologists to use medications known as checkpoint inhibitors to encourage T cells to eliminate tumor cells.

30 Mar 2019

Scientists develop new accurate computational method to enhance drug target stability

Scientists from the Moscow Institute of Physics and Technology, the Skolkovo Institute of Science and Technology, and the University of Southern California have developed a new computational method for the design of thermally stable G protein-coupled receptors that are of great help in creating new drugs.

30 Mar 2019