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A promising new therapy for rheumatoid arthritis

A promising new therapy for rheumatoid arthritis (RA) developed by researchers at the University of California, San Diego (UCSD) School of Medicine re-educates the body's immune system to prevent an attack against healthy joint tissue.

21 Apr 2004

Myriad Genetics advances drug for chemotherapy-induced nausea

Myriad Genetics, Inc. today released new data on MPC-4505, its Neurokinin-1 (NK1) receptor antagonist, a drug candidate for chemotherapy-induced nausea and vomiting (emesis). MPC-4505 is a potent, orally bioavailable, CNS-penetrating, highly selective NK1 antagonist.

20 Apr 2004

Preclinical data on Histamine's ability to prevent liver damage

These new results demonstrate the ability of histamine to prevent LPS-induced liver injury in a rodent model by showing efficacy when delivered in a manner mimicking oral administration.

19 Apr 2004

Menthol in topical creams relieves Osteoarthritis pain

A new study extends previous research and examines the effects of a topical cream consisting of cetylated fatty acids, along with the addition of menthol, on pain and functional performance in patients with knee osteoarthritis over the course of one week.

19 Apr 2004

Female hormone replacement therapy back on the agenda

Kronos Longevity Research Institute (KLRI) has announced plans for the Kronos Early Estrogen Prevention Study (KEEPS), a five-year study of female hormone replacement therapy aimed at providing prospective data on the risks and benefits of early menopausal hormonal intervention, particularly as it relates to the progression of atherosclerosis. Atherosclerosis is a medical condition in which fatty material is deposited along the walls of arteries.

17 Apr 2004

Oral treatment of chronic hepatitis C

Valeant Pharmaceuticals today presented 24-week data from Phase 2 clinical trials of Viramidine, a nucleoside (guanosine) analog Valeant is developing in oral form for the treatment of chronic hepatitis C (HCV) in conjunction with a pegylated interferon.

17 Apr 2004

New and Generic Drug Approvals from FDA

Apidra, Diazepam Injection, Dopram, Fosamax and others

16 Apr 2004

How to beat throat cancer

Rochesterian Jim Toole is looking forward to a warm summer filled with hearty picnic barbecues after beating throat cancer.

16 Apr 2004

Lack of exercise causes physical and psychological setbacks

Use it or lose it, fitness experts tell us. Now a new study offers evidence that the adage really does ring true – that a lack of exercise can not only cause physical setbacks, but also psychological setbacks as well.

16 Apr 2004

Differing views on virtual colonoscopy accuracy

Demonstrating clearly that not all virtual colonoscopies are equal, the study, published in the December 2003 issue of The New England Journal of Medicine and the American Journal of Roentgenology, found the results found using the Viatronix V3D-Colon system for primary 3D reading to be equal to or better than optical colonoscopy results.

14 Apr 2004

New research into Human Papilloma Virus (HPV) and Cervical Cancer

Cervical cancer is the second-most prevalent cancer in women and, despite encouraging improvements in screening leading to earlier detection, cervical cancer still kills many women every year. The risk of cervical cancer is increased by infection with certain types of human papilloma virus (HPV).

12 Apr 2004

New and Generic Drug Approvals from FDA

This newly approved or tentatively approved drug listing from the FDA is an interim page intended to provide timely information on new drug products as a more comprehensive page is developed.

12 Apr 2004

Diabetic retinopathy population will quadruple by 2012

Decision Resources, Inc., one of the world's leading research and advisory firms focusing on pharmaceutical and health care issues, finds that the drug-treated diabetic retinopathy population will quadruple by 2012.

12 Apr 2004

FDA approval of stomach acid suppressant

Wyeth Pharmaceuticals, a division of Wyeth, has announced that the U.S. Food and Drug Administration (FDA) approved the reformulation of the stomach acid suppressant, PROTONIX(R) I.V. (pantoprazole sodium) for Injection.

12 Apr 2004

Oral sildenafil improved exercise tolerance, cardiac output and quality of life in 22 patients with primary pulmonary hypertension

Oral sildenafil (Viagra®) improved exercise tolerance, cardiac output and quality of life in 22 patients with primary pulmonary hypertension, according to the results of the first randomized, placebo-controlled, double-blind, crossover study, reported in the April 7, 2004 issue of the Journal of the American College of Cardiology.

6 Apr 2004

Cephalosporins three times more effective than penicillin

Pediatricians treating a child who has strep throat should reconsider the role of penicillin given that a newer class of antibiotics called cephalosporins are three times more effective, according to a study being published in the April issue of Pediatrics. The findings will spark widespread debate, because they contradict long-established guidelines from the American Academy of Pediatrics, American Heart Association,and World Health Organization.

5 Apr 2004

NeoRx Corporation acquires worldwide rights to platinum-based anti-cancer agent

NeoRx Corporation today announced that it has acquired from AnorMED Inc. the worldwide exclusive rights, excluding Japan, to develop, manufacture and commercialize AMD473, a platinum-based anti-cancer agent. AMD473 has been administered to more than 500 cancer patients in phase I and phase II clinical trials, demonstrating anti-cancer activity in a wide range of tumors and a manageable safety profile. NeoRx expects to initiate clinical studies of AMD473 in one or more cancer indications in the second half of this year.

5 Apr 2004

Heart disease can be reduced substantially by regularly treating existing gum infections

Reinforcing the relationship between periodontal disease and heart disease, oral biologists from the University at Buffalo have shown that levels of two inflammatory proteins known to raise the risk of heart disease can be reduced substantially by regularly treating existing gum infections.

31 Mar 2004

FDA has approved Zyprexa, injectable anti-psychotic drug

Physicians have a new fast-acting option for controlling the potentially crippling effects of acute agitation in patients suffering with schizophrenia and bipolar mania. The U.S. Food and Drug Administration (FDA) has approved Zyprexa® IntraMuscular (olanzapine for injection), an injectable form of Lilly's top-selling medication.

30 Mar 2004

Comparative genomics to cast new light on other spirochete microbes

Three centuries after a pioneering Dutch microbiologist first observed the spiral-shaped oral pathogen Treponema denticola, scientists have deciphered the bacterium’s entire DNA sequence and used comparative genomics to cast new light on other spirochete microbes.

29 Mar 2004