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Novel immunotherapy targeting myeloid immune cells reduces tumor growth

Checkpoint inhibitors, a type of immunotherapy, that target myeloid immune cells and slow tumor growth were discovered by a team from the Perelman School of Medicine at the University of Pennsylvania and other institutions.

27 May 2020

Ivy Center opens new clinical trial to evaluate experimental drug cocktail for glioblastoma

The Ivy Brain Tumor Center at Barrow Neurological Institute announced that patient recruitment has opened for a new Phase 0 clinical trial to evaluate two targeted therapy drugs, abemaciclib and LY3214996.

27 May 2020

Researchers are taking inventory of drugs used to treat COVID-19

With doctors and researchers around the world searching for effective treatments for COVID-19, many drugs approved to treat other diseases are being used in hopes that they'll be effective against the virus, a use that's known as "off-label."

27 May 2020

COVID-19 Rapid Research Fund allows coronavirus research in Ontario and London

Sepsis is a life-threatening condition. It occurs when the body's response to an infection is out of balance, triggering hyperinflammation that can damage multiple organs.

27 May 2020

A promising method for treating triple-negative breast cancer

Researchers at the University of Queensland may have found a way to improve treatment of triple-negative breast cancer.

27 May 2020

A new approach to predict the evolutionary mechanisms of melanoma

Melanoma is a malignant tumour resulting from the transformation of melanocytes, the cells in the skin that undertake to synthesise melanin, a complex polymer which protects us from the negative effects of solar radiation.

27 May 2020

Study highlights the benefits of palliative care for heart failure patients

Palliative care is valuable for heart failure patients, and, for those who are hospitalized, it can significantly lower the risk of repeated hospital admissions and the need for invasive procedures such as mechanical ventilation and defibrillator implantation, according to new research published today in the Journal of the American Heart Association, an open-access journal of the American Heart Association.

27 May 2020

Study: High level of anxiety is linked to depression

Led by King's College London in collaboration with the University of Zimbabwe and the London School of Hygiene & Tropical Medicine, and published in The Lancet's EClinicalMedicine journal, the research examined a group of people with depression in Zimbabwe and found that people are nearly three times more likely to suffer this illness long-term if they also have a high level of anxiety.

27 May 2020

Identifying the Starting Points for COVID19 Treatment

News-Medical spoke to researchers from the German Primate Center on their research in determining the activation sequence of the SARS-CoV-2 virus.

27 May 2020

New book series brings updated reviews on diabetes and obesity

Frontiers in Clinical Drug Research - Diabetes and Obesity is a book series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of two metabolic diseases - diabetes and obesity.

27 May 2020

Updates on stem cell therapeutics and regenerative medicine

Stem cell and regenerative medicine research is an important area of clinical research which promises to change the face of medicine as it will be practiced in the years to come.

27 May 2020

Stand Up To Cancer hails FDA approval of new treatment option for aggressive prostate cancer

A recent FDA approval supported by Stand Up To Cancer research provides a new treatment option for patients with an aggressive form of prostate cancer.

27 May 2020

Meta-analysis of latest second-line treatments for status epilepticus

Status epilepticus (SE) is the most common neurologic emergency, with rates estimated between 1.3 and 81 cases per 100,000 people per year.

27 May 2020

Investigational antiviral superior to standard of care for treating COVID-19 patients

The investigational antiviral remdesivir is superior to the standard of care for the treatment of COVID-19, according to a report published today in The New England Journal of Medicine.

27 May 2020

Study finds very low level of SARS-CoV-2 in two San Francisco Bay areas

A new study published on the preprint server medRxiv in May 2020 reports a very low prevalence of antibodies in two separate populations living in the San Francisco Bay Area.

26 May 2020

Antimalarial drug shows promise as potential therapy for aggressive brain cancer

Glioblastoma multiforme is an aggressive form of cancer in the brain that is typically fatal. But new findings by VCU Massey Cancer Center and VCU Institute of Molecular Medicine researchers could help increase the effectiveness of the most common current treatments with the addition of lumefantrine, an FDA-approved drug used to treat malaria.

26 May 2020

Deaths from COVID-19 appear to be on the decline in Italian provinces

Researchers in Italy have found that the proportion of people dying from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may be on the decline in Italy.

26 May 2020

New AI tool could predict risk of lung cancer recurrence

Computer scientists working with pathologists have trained an artificial intelligence tool to determine which patients with lung cancer have a higher risk of their disease coming back after treatment, as part of Cancer Research UK’s landmark TRACERx study.

26 May 2020

Researchers identify genetic mechanisms that produce radioresistance in cancer cells

Cancer stem cells are a cell type that was previously little known. They are resistant to irradiation and prevent the effective treatment of many types of cancer. A research group from Innsbruck has now identified two genetic mechanisms that produce this radioresistance.

26 May 2020

Challenges of diagnosing Lyme disease in the absence of classic symptoms

Lyme disease can have unusual presentations. Physicians and the public should be aware of its different manifestations, as people spend more time outside in the warmer weather and as the areas in Canada where the black legged tick is found expand.

26 May 2020