Malignant News and Research

RSS

International study identifies new drug target for treating glioblastoma

A new international study co-led by Cleveland Clinic has identified a new drug target for treating glioblastoma. This target is part of a never-before defined cellular pathway found to contribute to the spread and proliferation of a dangerous subset of cancer cells, called glioma stem cells.

22 Aug 2019

FDA clears its IND for new immunotherapeutic for treating prostate cancer

Calibr, the drug development division of Scripps Research, announced today that the U.S. Food and Drug Administration has cleared its investigational new drug application for CCW702, a novel immunotherapeutic for the treatment of patients with metastatic castration-resistant prostate cancer.

21 Aug 2019

Researchers develop new gene editing system that could be used for anticancer immunotherapy

Dr. Mihue Jang and her group at the Center for Theragnosis of the Korea Institute of Science and Technology announced that they have developed a new gene-editing system that could be used for anticancer immunotherapy through the simultaneous suppression of proteins that interfere with the immune system expressed on the surface of lymphoma cells and activation of cytotoxic T lymphocyte, based on the results of joint research conducted with Prof. Seokmann Hong and his group at Sejong University.

20 Aug 2019

Scientists identify hereditary pancreatic cancer risk mutation

Scientists studying a highly cancer-prone family have identified a rare, inherited gene mutation that dramatically raises the lifetime risk of pancreatic and other cancers.

12 Aug 2019

New T cell detection method promises personalized immunotherapy for melanomas

An important new study shows that better T cell detection is now possible using revolutionary technology. T cells are a type of lymphocyte, which in turn belongs to the diverse family of immune cells. They take part in cancer fighting as well as in most other immune responses.

12 Aug 2019

Study reveals surprising discoveries about poorly understood glioblastoma

Glioblastoma, a cancer that arises in the brain's supporting glial cells, is one of the worst diagnoses a child can receive. The grade IV, highly malignant tumor aggressively infiltrates healthy brain tissue, and most children die of the disease within one to two years of diagnosis, similar to adults.

12 Aug 2019

Longer-lived, but less toxic drug may work better for pancreatic cancer

Unlike many other cancers, most pancreatic tumors are rock hard.

9 Aug 2019

Study shows how cigarette smoke drives tumor aggressiveness in head and neck cancer

Head and neck cancer is the sixth most common cancer in the world. The vast majority of cases are head and neck squamous cell carcinoma, a type of cancer that arises in the outer layer of the skin and mucous membranes of the mouth, nose and throat.

8 Aug 2019

New nanovaccine for deadly skin cancer

Tel Aviv scientists have published their version of a vaccine against the deadly skin cancer malignant melanoma, which arises from the pigment producing cells of the skin. This is the most feared form of skin cancer, with a high tendency to metastasize to distant parts of the body, including the brain.

6 Aug 2019

New blood test can detect clinically significant prostate cancer in high-risk patients

An international research team at Mahidol University in Bangkok, Thailand, has developed a new blood test capable of detecting clinically significant prostate cancer in high-risk patients, as reported in the medical journal Cancers on 27 July 2019.

6 Aug 2019

Research offers molecular details of pancreatic cancer's ability to invade and evade

Two known gene mutations induce pathways that enhance pancreatic cancer's ability to invade tissues and evade the immune system.

6 Aug 2019

Biomarkers reveal increase in thyroid cancer incidence among WTC responders

The incidence of thyroid cancer among first responders who volunteered or were employed as firefighters, rescue personnel and cleanup workers at Ground Zero in New York on or after September 11, 2001, is three times higher than that in the general population.

5 Aug 2019

Novel medical device protects healthy organs from radiation exposure during particle therapy

Kobe University and Alfresa Pharma Corporation develop a novel medical device with non-woven fabric style made of bioabsorbable material.

5 Aug 2019

FDA approves first therapy for symptomatic tenosynovial giant cell tumor

Today, the U.S. Food and Drug Administration granted approval to Turalio (pexidartinib) capsules for the treatment of adult patients with symptomatic tenosynovial giant cell tumor (TGCT) associated with severe morbidity or functional limitations and not responsive to improvement with surgery.

3 Aug 2019

Canine tumor appears immortal, spreads from dog to dog across all boundaries

A new study has revealed that the oldest and most widespread cancer cell line in the world is the contagious dog cancer called CTVT. This is among the few transmissible cancers. The canine transmissible venereal tumor (CTVT) has been found to cause sexually transmitted tumors in dogs for over 8,500 years.

2 Aug 2019