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Trauma may cause long-lasting effects even in people without PTSD

Trauma may cause distinct and long-lasting effects even in people who do not develop PTSD (post-traumatic stress disorder), according to research by scientists working at the University of Oxford's Department of Psychiatry. It is already known that stress affects brain function and may lead to PTSD, but until now the underlying brain networks have proven elusive.

4 Aug 2015

New study estimates link between coffee consumption habits and incidence of mild cognitive impairment

A new study by researchers at the University of Bari Aldo Moro, Bari, Italy, Geriatric Unit & Laboratory of Gerontology and Geriatrics, IRCCS "Casa Sollievo della Sofferenza", San Giovanni Rotondo, Foggia, Italy, and Istituto Superiore di Sanità, Roma, Italy, estimates the association between change or constant habits in coffee consumption and the incidence of mild cognitive impairment (MCI), evaluating 1,445 individuals recruited from 5,632 subjects, aged 65-84 year old, from the Italian Longitudinal Study on Aging (ILSA), a population-based sample from eight Italian municipalities with a 3.5-year median follow-up.

29 Jul 2015

Kessler Foundation, University of Bordeaux team up to study emotional processing deficits in MS people

Kessler Foundation received $65,500 as part of a two-year $140,000 grant from the ARSEP Foundation of France to the University of Bordeaux, to launch a collaborative study of emotional processing deficits in people with multiple sclerosis (MS). Helen Genova, Ph.D., and Jean Lengenfelder, Ph.D., of Kessler Foundation and Bruno Brochet, M.D., Ph.D., of the University of Bordeaux are the principal investigators.

17 Jul 2015

Gene therapy used for sight restoration also strengthens visual pathways in the brain

Since 2007, clinical trials using gene therapy have resulted in often-dramatic sight restoration for dozens of children and adults who were otherwise doomed to blindness. Now, researchers from the Perelman School of Medicine at the University of Pennsylvania and The Children's Hospital of Philadelphia, have found evidence that this sight restoration leads to strengthening of visual pathways in the brain, published this week in Science Translational Medicine.

16 Jul 2015

Alzheimer's disease may be 'at work' years ahead of actual symptoms, say IU researchers

The best-known genetic variant linked to Alzheimer's disease may be "at work" promoting deposits of plaque in the brain long before any symptoms of the disease can be measured on tests, according to a national research study led by Indiana University School of Medicine investigators.

14 Jul 2015

Shape of the cerebral cortex strongly correlates with genetic ancestry

Researchers at the University of California, San Diego and the School of Medicine have found that the three-dimensional shape of the cerebral cortex - the wrinkled outer layer of the brain controlling many functions of thinking and sensation - strongly correlates with ancestral background.

12 Jul 2015

Study: Brain activity changes after memory retraining in TBI patients

Kessler Foundation researchers published results of their TBI-MEM trial, the first study to demonstrate significant changes in cerebral activation after memory retraining in individuals with traumatic brain injury.

9 Jul 2015

People who survive stroke may experience accelerated and persistent decline in cognitive function

In a study that included nearly 24,000 participants, those who experienced a stroke had an acute decline in cognitive function and also accelerated and persistent cognitive decline over 6 years, according to an article in the July 7 issue of JAMA.

8 Jul 2015

Georgia State University-led study identifies structural brain abnormalities in schizophrenia patients

Structural brain abnormalities in patients with schizophrenia, providing insight into how the condition may develop and respond to treatment, have been identified in an internationally collaborative study led by a Georgia State University scientist.

7 Jul 2015

Kessler Foundation receives $3 million to improve cognition and mobility of people with TBI

The New Jersey Commission on Brain Injury Research awarded $3 million in grants to Kessler Foundation, half of its total grant distribution in 2015, to improve cognition and mobility of individuals with traumatic brain injury (TBI).

1 Jul 2015

People with specific gene variant at greater risk of developing depressions

People born with a particular gene variant have a greater risk of developing depressions, a recent study from the Department of Psychology at The University of Oslo shows.

29 Jun 2015

Different neurobiological pathways lead to expression of Alzheimer's disease

The amyloid cascade hypothesis of Alzheimer's disease (AD) posits that sticky aggregations or plaques of amyloid-beta peptides accumulate over time in the brain, triggering a series of events that ultimately result in the full-blown neurodegenerative disorder. The hypothesis has been a major driver of AD research for more than 20 years.

26 Jun 2015

10-week reading intervention improves brain activity in autistic children

Ten weeks of intensive reading intervention for children with autism spectrum disorder was enough to strengthen the activity of loosely connected areas of their brains that work together to comprehend reading, University of Alabama at Birmingham researchers have found.

24 Jun 2015

NTCELL Phase I/IIa clinical study meets primary endpoint in patients with Parkinson’s disease

Living Cell Technologies Limited today announced results from a Phase I/IIa clinical study of NTCELL, an experimental regenerative cell therapy being studied as a disease-modifying agent in Parkinson’s disease. The study, conducted in four patients in New Zealand, met its primary endpoint of safety, showing NTCELL implantation was well tolerated, with no adverse events considered to be related to NTCELL.

15 Jun 2015

Research: Interaction between cortical and subcortical brain regions highlights role of hypersensitivity in ASD

The increased interaction between cortical and subcortical brain regions highlights the central role of hypersensitivity and other sensory symptoms in defining Autism Spectrum Disorder (ASD).

12 Jun 2015

Diagnosing brain lesions in children can be challenging, report Loyola physicians

Brain lesions in children can be especially challenging to diagnose, according to a report in the journal Frontiers in Neurology by a multidisciplinary team of Loyola University Medical Center physicians.'

10 Jun 2015

Study can help spur beneficial lifestyle changes in patients to reduce Alzheimer's risk

Armed with new knowledge about how neurodegenerative diseases alter brain structures, increasing numbers of neurologists, psychiatrists and other clinicians are adopting quantitative brain imaging as a tool to measure and help manage cognitive declines in patients. These imaging findings can help spur beneficial lifestyle changes in patients to reduce risk for Alzheimer's disease.

5 Jun 2015

People with high moral reasoning skills show increased gray matter in brain

Individuals with a higher level of moral reasoning skills showed increased gray matter in the areas of the brain implicated in complex social behavior, decision making, and conflict processing as compared to subjects at a lower level of moral reasoning, according to new research from the Perelman School of Medicine and the Wharton School of the University of Pennsylvania in collaboration with a researcher from Charité Universitätsmediz in Berlin, Germany.

4 Jun 2015

Researchers examine neuroimaging findings in children with sports-related concussions

Researchers from the Canada North Concussion Network in Manitoba examined neuroimaging studies obtained in children and adolescents with sports-related concussions and found that the images appeared normal in 78% of cases.

3 Jun 2015

Iron may underlie effect of Alzheimer’s risk allele

Ferritin in the cerebrospinal fluid of patients with Alzheimer’s disease is associated with the APOE ε4 risk allele and predicts cognitive outcomes, a study shows.

29 May 2015