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Moderna’s COVID-19 vaccine provides durable protection against SARS-CoV-2 delta in macaques

Researchers in the United States have conducted a study showing that Moderna’s coronavirus disease 2019 (COVID-19) vaccine provided durable protection against the B.1.617.2 (delta) variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in rhesus macaques.

26 Oct 2021

A high-throughput pipeline for identifying nanobodies that target and neutralize SARS-CoV-2

Researchers in the United States have developed a cost-effective, high-throughput pipeline for identifying effective nanobodies that target and neutralize severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

26 Oct 2021

Hyperimmune antibody produced in horses may be an efficient approach to combat covid-19

A study conducted by a consortium of Brazilian researchers has demonstrated that a hyperimmune serum consisting of purified antibody fragments produced in horses may be an efficient approach to combat covid-19.

26 Oct 2021

UQ researchers find that SARS-CoV-2 virus does not infect blood vessels

The SARS-CoV-2 virus does not infect blood vessels, despite the high risk of blood clots to COVID-19 patients, University of Queensland researchers have found.

26 Oct 2021

Study finds SARS-CoV-2 infection is proportional to cell surface ACE2 levels

Researchers from Oregon State University have developed a system to assess the ability of SARS-CoV-2 to bind to ACE2 orthologs.

26 Oct 2021

Sexually dimorphic placental antibody transfer during SARS-CoV-2 infection

In a paper recently published in the journal Science Translational Medicine by Bordt et al. (October 19th, 2021), maternal SARS-CoV-2 infections are studied with particular regard to maternal-fetal antibody transfer and virus-induced placental interferon responses, finding a sexually dimorphic response that results in lesser antibody transfer to the male fetus.

26 Oct 2021

Immune response to mRNA COVID vaccines delayed in pregnant women

Researchers in the United States have conducted comprehensive profiling of humoral immune responses in pregnant, lactating, and non-pregnant women following coronavirus disease 2019 (COVID-19) messenger RNA (mRNA) vaccination to probe differences in vaccine-induced immunity.

25 Oct 2021

N501Y mutation in SARS-CoV-2 Delta variant is key to breakthrough infections

A study in the Philadelphia area found that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants evolve to become more contagious and resistant to COVID-19 vaccines. In addition, depending on the sublineage, SARS-CoV-2 variants such as the Delta variant led to a three-fold increased risk for vaccine breakthrough cases.

25 Oct 2021

Regulating blood insulin levels in obese, diabetic patients may help reduce COVID-19 risk

Keeping blood insulin levels within strict, healthy parameters is a daily goal for people with diabetes. But now, researchers from Japan have found that regulating blood insulin levels may even help lower the risk of getting COVID-19.

25 Oct 2021

A new vaccine approach that could prevent future pandemics

News-Medical speaks to Professor Tomohiro Kurosaki about how he has developed a new vaccine approach that could prevent future pandemics.

25 Oct 2021

Are non-human primates at risk of SARS-CoV-2 exposure through wastewater contact?

Researchers have been investigating the potential for SARS-CoV-2 to spread to NHP through wastewater.

25 Oct 2021

Molecular features of SARS-CoV-2 variant receptor binding

Researchers have been investigating the changes in receptor binding in these variants that increase the danger they pose.

25 Oct 2021

Study finds FDA-approved drug has potent antiviral activity against SARS-CoV-2 and variants of concern

A new study aimed to examine the antiviral potential of atovaquone against the original SARS-CoV-2 strain and other variants of concern.

25 Oct 2021

Study suggests seropositive individuals produce anti-SARS-CoV-2 antibodies with improved potency and breadth

Researchers isolated single cells among individuals with and without prior infection with the SARS-CoV-2 vaccinated with BNT162b2 mRNA vaccine and compared the nature of the neutralizing antibody response against the original Wuhan virus and the subsequent variants.

25 Oct 2021

Spike Protein News and Research

Moderna’s COVID-19 vaccine provides durable protection against SARS-CoV-2 delta in macaques

A high-throughput pipeline for identifying nanobodies that target and neutralize SARS-CoV-2

Hyperimmune antibody produced in horses may be an efficient approach to combat covid-19

UQ researchers find that SARS-CoV-2 virus does not infect blood vessels

Study finds SARS-CoV-2 infection is proportional to cell surface ACE2 levels

Sexually dimorphic placental antibody transfer during SARS-CoV-2 infection

Immune response to mRNA COVID vaccines delayed in pregnant women

N501Y mutation in SARS-CoV-2 Delta variant is key to breakthrough infections

Regulating blood insulin levels in obese, diabetic patients may help reduce COVID-19 risk

A new vaccine approach that could prevent future pandemics

Are non-human primates at risk of SARS-CoV-2 exposure through wastewater contact?

Molecular features of SARS-CoV-2 variant receptor binding

Study finds FDA-approved drug has potent antiviral activity against SARS-CoV-2 and variants of concern

Study suggests seropositive individuals produce anti-SARS-CoV-2 antibodies with improved potency and breadth

SARS-CoV-2 Delta variant transmitted by fully vaccinated individuals in Provincetown, Massachusetts

Targeting SARS-CoV-2 with Chaga mushroom – a natural antiviral compound

A comparison between Pfizer/BioNTech's and Sinopharm's SARS-CoV-2 vaccines

Immune evasion by SARS-CoV-2 facilitated by a mutational hotspot in the NTD

Mu and C.1.2 variant spike proteins partially resistant to neutralization by vaccine-elicited antibodies

Immunogenicity and efficacy of adjuvanted SARS-CoV-2 beta variant subunit booster in rhesus macaques

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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