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FDA approves Perrigo's ANDA for OTC Miconazole Nitrate Vaginal Cream and Suppository

Perrigo Company today announced that it has received final approval from the U.S. Food and Drug Administration for its abbreviated new drug application for over-the-counter (OTC) Miconazole Nitrate Vaginal Cream and Suppository, a generic to Monistat® -1 Combination Pack. Perrigo expects to begin shipping immediately.

4 Jun 2010

Yeast produce a hormone that triggers fungal cells to become more infectious

In their ongoing studies of how yeast (fungi) can infect a host and cause disease, a research team at the Life Sciences and Bioengineering Center at Worcester Polytechnic Institute (WPI) has made an unexpected discovery. They found that yeast produce a hormone previously known to be made by plants, and that the presence of that hormone in sufficient quantity within the yeast's immediate environment triggers the fungal cells to become more infectious.

29 May 2010

HZI researchers develop new method to produce insulin for treatment of diabetes

More than eight million diabetics live in Germany. Diabetes is not restricted to our prosperous society and the highest growth rates often occur in countries with aspiring economies such as in Asia. Worldwide, more than 285 million people suffer from this illness; with 50 million diabetics, India is the country with the most people affected by this disease.

27 May 2010

Naturxan expands production and distribution capabilities to provide worldwide availability of Aquasta

Naturxan, LLC, a joint venture between Archer Daniels Midland Company and Igene Biotechnology, Inc., today announced that it has completed an expansion of its production and distribution capabilities to provide worldwide availability of Aquasta, a naturally sourced astaxanthin made from Phaffia yeast for enriching and pigmenting salmon and trout consuming aquaculture feeds.

27 May 2010

Rice University researcher receives 2010 Glycerine Innovation Award

Escherichia coli - E. coli for short - is often identified as a bacterium that contributes to foodborne illness. But research led by a Rice University scientist has discovered ways to use a safe, non-pathogenic E. coli to convert glycerine into high value fuels and chemicals.

21 May 2010

JCVI researchers construct first self-replicating, synthetic bacterial cell

Researchers at the J. Craig Venter Institute (JCVI), a not-for-profit genomic research organization, published results today describing the successful construction of the first self-replicating, synthetic bacterial cell. The team synthesized the 1.08 million base pair chromosome of a modified Mycoplasma mycoides genome.

21 May 2010

Genes living in the outskirts of chromosomes more prone to duplication: Study

The ability of yeast cells to convert sugar to alcohol, the key process in the production of beer and wine, can be attributed to a remarkable evolutionary process. The genes that allow yeast to digest sugars in fruits and grains have been duplicated several times over the course of time - allowing for optimal conversion of different types of sugars (such as sucrose and maltose) into alcohol.

17 May 2010

Research sheds light on early embryogenesis, genetic disease

Chromosome 22q11 deletion syndrome (also known as DiGeorge syndrome) is the most common human chromosome deletion syndrome, having an estimated incidence of at least one in 4,000 live births.

15 May 2010

Scientists look for new ways to fight TB

Scientists looking for new ways to fight tuberculosis have their sights set on a structure essential to the bacterium's survival. Disabling this structure could kill the microbes in the infected host and thwart TB infections. In a study appearing online May 11, 2010, in EMBO J, the journal of the European Molecular Biology Organization, scientists from the U.S. Department of Energy's Brookhaven National Laboratory, Stony Brook University, and Weill Cornell Medical College describe new features of how this structure, known as a proteasome, is put together and how it works.

14 May 2010

NIH awards CSU biochemists $7.8M grant to study gene regulation within cells

A team of top biochemists at Colorado State University will investigate how chromosomes untangle to expose genes that dictate cell behavior - a unique project that could have a significant impact on understanding human health.

5 May 2010

Study could provide new strategies to prevent hospital-acquired infections

A bacterial pathogen can communicate with yeast to block the development of drug-resistant yeast infections, say Irish scientists writing in the May issue of Microbiology. The research could be a step towards new strategies to prevent hospital-acquired infections associated with medical implants.

3 May 2010

Cellular IPOD plays role in prion biology

Cells take advantage of a biologically ancient compartment to sequester prions, an action that can initially prevent the prions’ phenotypic expression, according to Whitehead Institute researchers. While in this compartment, less heritable prion plaques mature to a more transmissible state.

27 Apr 2010

New research project to make anti-malarial drugs more affordable in Third World countries

Dr Geoff Brown, from the University of Reading's Department of Chemistry, is beginning a £400,000 project that could prove vital for the developing world in its ongoing fight against malaria. His research aims to make anti-malarial drugs more affordable in Third World countries where more than 1.5 million people die of the disease every year.

24 Apr 2010

Potential mate's signal activates molecular switch

A mystery about the mechanism behind sexual mate selection has been resolved. According to a new study published in the journal Nature, Universit- de Montr-al researchers have discovered a molecular switch that becomes activated in response to a potential mate's signal. Simply put, an organism knows that a potential mate is close-by and healthy enough to mate.

19 Apr 2010

New insights into yeast cells may help identify cancer cells and stem cells development: Study

Yeast cells decide whether to have sex with each other within two minutes of meeting, according to new research published today in Nature. One of the authors of the study, from Imperial College London, says the new insights into how yeast cells decide to mate could be helpful for researchers looking at how cancer cells and stem cells develop.

19 Apr 2010

NSF Faculty Early Career Development Award for Zhihao Zhuang

Zhihao Zhuang, assistant professor in the Department of Chemistry and Biochemistry at the University of Delaware, has won the National Science Foundation Faculty Early Career Development Award.

17 Apr 2010

Calorie restriction may help people to lead longer and healthier lives

Organisms from yeast to rodents to humans all benefit from cutting calories. In less complex organisms, restricting calories can double or even triple lifespan. It's not yet clear just how much longer calorie restriction might help humans live, but those who practice the strict diet hope to survive past 100 years old.

16 Apr 2010

Sorrento Therapeutics completes construction of fully human mAbs library

Sorrento Therapeutics, Inc. today announced that it has completed the construction of an extensive library of full-length, fully human monoclonal antibodies (mAbs). Initial analysis indicates a potential diversity of more than one trillion unique mAbs. The company believes this makes its library the largest full-length, fully human antibody library available for drug discovery and development partnerships.

15 Apr 2010

Scientists uncover new genes responsible for cancer, deafness

From deep within the genomes of organisms as diverse as plants, worms and yeast, scientists have uncovered new genes responsible for causing human diseases such as cancer and deafness.

15 Apr 2010

Researchers investigate effects of nanoparticles on yeast

Nanoparticles are already widely used in everyday products such as cosmetics, textiles, dyes, and paints. It is quite possible that these minute fragments of matter may in future not only come to play a crucial role in medicine and pharmacology, but also in the food and biotechnology industries. The latest research currently being conducted in India has shown that nanoparticles can promote the growth of fungi and even assist plant growth.

12 Apr 2010