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FDA approves Pfizer's Prevnar 13 pneumococcal conjugate vaccine

Pfizer Inc. announced today that the United States Food and Drug Administration has granted approval for Prevnar 13™ (Pneumococcal 13-valent Conjugate Vaccine [Diphtheria CRM197 Protein]), the Company’s 13-valent pneumococcal conjugate vaccine.

25 Feb 2010

Novelos Therapeutics' NOV-002 Phase 3 NSCLC trial fails to meet primary survival endpoint

Novelos Therapeutics, Inc., a biopharmaceutical company focused on the development of therapeutics to treat cancer and hepatitis, today announced that the primary endpoint of improvement in overall survival was not met in Novelos’ pivotal Phase 3 trial in advanced non-small cell lung cancer (NSCLC) studying its lead product, NOV-002, in combination with first-line chemotherapy. Detailed trial results are expected to be presented via appropriate scientific venue later this year.

24 Feb 2010

Over-produced PKC-iota oncogene linked to poor pancreatic cancer patient survival

Researchers at the Mayo Clinic campus in Florida have found that PKC-iota (PKC), an oncogene important in colon and lung cancers, is over-produced in pancreatic cancer and is linked to poor patient survival. They also found that genetically inhibiting PKC in laboratory animals led to a significant decrease in pancreatic tumor growth and spread.

24 Feb 2010

Arsenic exposure may increase cancer risk, says study

Researchers have found a new oncogenic signaling pathway by which the environmental toxin arsenic may lead to adverse health effects, including bladder cancer. These study results are published in Cancer Research, a journal of the American Association for Cancer Research.

24 Feb 2010

BSD2000 deep hyperthermia combined with chemotherapy improves quality of life in NSCLC patients

BSD Medical Corporation today announced that a study titled “BSD2000 Deep Hyperthermia Combined with Chemotherapy of PT regimen in Patients with Non-small Cell Lung Cancer” has been published in the current issue of The Chinese Journal of Lung Cancer (February 2010;13(2):132–135) by Yang, Zhao, and Wang.

24 Feb 2010

Poniard Pharmaceuticals enters into $20M committed equity financing facility with Commerce Court Small Cap Value Fund

Poniard Pharmaceuticals, Inc., a biopharmaceutical company focused on innovative oncology therapies, today announced that it has entered into a committed equity financing facility under which it may sell up to $20 million of its registered common stock to Commerce Court Small Cap Value Fund, Ltd. over an approximately 18-month period. Poniard is not obligated to utilize any of the facility and remains free to enter into other financing transactions.

24 Feb 2010

Researchers study how laser-induced ultrasound could help identify the stage of melanoma

Knowing the stage of a patient's melanoma is important when choosing the best course of treatment. When the cancer has progressed to the lymph nodes, a more aggressive treatment is needed. Examining an entire lymph node for cancer takes much effort and time; a new technique might help make the process more efficient.

24 Feb 2010

Presence of SIBLING proteins in premalignant oral lesions may predict oral cancer

The presence of certain proteins in premalignant oral lesions may predict oral cancer development, Medical College of Georgia researchers said.

24 Feb 2010

Researchers receive grant to study how ILD appears in patients with autoimmune diseases

Researchers at the University of Cincinnati Interstitial Lung Disease Center have received a grant from the National Heart, Lung and Blood Institute to study ways ILD first appears in certain patient groups with autoimmune diseases and how to more efficiently diagnose and treat it.

24 Feb 2010

Cephalon to acquire Ception Therapeutics following positive clinical study of eosinophilic asthma

Cephalon, Inc. (Nasdaq: CEPH) announced today that it has exercised its option to acquire Ception Therapeutics, Inc., following receipt of positive data from a clinical study in adults with eosinophilic asthma.

23 Feb 2010

Aradigm initiates dosing in Phase 2b trial of inhaled liposomal ciprofloxacin formulations in BE patients

Aradigm Corporation today announced that it dosed the first patient in the U.S. as part of its ORBIT-1 (Once-daily Respiratory Bronchiectasis Inhalation Treatment) trial, an international, randomized, double-blind, placebo-controlled Phase 2b study designed to evaluate the Company's inhaled liposomal ciprofloxacin (ARD-3100) in patients with non-cystic fibrosis bronchiectasis (BE) under a U.S. IND. This orphan disease indication is a chronic, severe respiratory disease and there are currently no approved treatments for this disease in the U.S.

23 Feb 2010

Menssana Research develops 85% accurate breath test for pulmonary tuberculosis

A new breath test can detect active pulmonary tuberculosis, according to a report to be published in the journal "Tuberculosis."

23 Feb 2010

Multidisciplinary rounds may facilitate implementation of best clinical practices: Study

Multidisciplinary care teams consisting of clinicians, nurses and other health care professionals appear to be associated with a lower risk of death among patients in the intensive care unit, according to a report in the February 22 issue of Archives of Internal Medicine, one of the JAMA/Archives journals. A second report finds that an increasing number of surgical patients are being managed jointly by a surgeon and another clinician, such as a hospitalist or internal medicine sub-specialist.

23 Feb 2010

FDA issues approval for Gileads's Cayston for respiratory symptoms in cystic fibrosis

Gilead Sciences, Inc. today announced that the U.S. Food and Drug Administration (FDA) has granted marketing approval for Cayston® (aztreonam for inhalation solution) as a treatment to improve respiratory symptoms in cystic fibrosis patients with Pseudomonas aeruginosa. Cayston’s safety and efficacy have not been established in pediatric patients below the age of 7, patients with forced expiratory volume in one second of less than 25 percent or greater than 75 percent predicted, or patients colonized with Burkholderia cepacia.

23 Feb 2010

Multidisciplinary, team-based approach can reduce mortality rates in ICUs

The severe shortage of specially-trained intensivist physicians has hospital intensive care units (ICUs) nationwide struggling to staff units with critical care teams led by intensivists, even though the presence of these specially trained physicians reduces the risk of death for patients in the ICU.

23 Feb 2010

Lilly, Merck, Pfizer collaborate to accelerate research on commonly-diagnosed cancer

Eli Lilly and Company, Merck (also known as Merck Sharp & Dohme (MSD) outside the USA and Canada), and Pfizer Inc. today announced the formation of the Asian Cancer Research Group, Inc., an independent, not-for-profit company established to accelerate research and ultimately improve treatment for patients affected with the most commonly-diagnosed cancers in Asia.

23 Feb 2010

Belgian Hospital completes certification training for SynCardia's Total Artificial Heart implant

On Feb. 25 & 26, the surgical team from Onze Lieve Vrouw (OLV) Hospital Aalst, led by surgeons Ivo Deblier, MD, and Karl Dossche, PhD, and accompanied by anesthesiologist Koen De Decker, MD, will become the first hospital in Belgium and the 50th hospital in the world to complete the first phase of certification training to implant the SynCardia temporary CardioWest™ Total Artificial Heart.

23 Feb 2010

New cardiac imaging technique reduces radiation exposure compared to standard helical scan

In a new study published in the March issue of Radiology, researchers from Columbia University and the National Heart, Lung and Blood Institute have determined that an imaging exam of the heart using the latest generation of CT technology exposes patients to as much as 91 percent less radiation than standard helical CT scanning.

23 Feb 2010

Hospital-acquired infections increase mortality rate and healthcare costs

Two common conditions caused by hospital-acquired infections (HAIs) killed 48,000 people and ramped up health care costs by $8.1 billion in 2006 alone, according to a study released today in the Archives of Internal Medicine.

23 Feb 2010

Black women are more prone to peripartum cardiomyopathy around childbirth time

A study examining the incidence of peripartum cardiomyopathy in women who gave birth at a Medical College of Georgia's teaching hospital between July 2003 and July 2008, showed that while 55 percent of the women were white, 93 percent of those who developed cardiomyopathy were black, said Dr. Mindy B. Gentry, an MCG cardiologist.

23 Feb 2010

Lungs News and Research

FDA approves Pfizer's Prevnar 13 pneumococcal conjugate vaccine

Novelos Therapeutics' NOV-002 Phase 3 NSCLC trial fails to meet primary survival endpoint

Over-produced PKC-iota oncogene linked to poor pancreatic cancer patient survival

Arsenic exposure may increase cancer risk, says study

BSD2000 deep hyperthermia combined with chemotherapy improves quality of life in NSCLC patients

Poniard Pharmaceuticals enters into $20M committed equity financing facility with Commerce Court Small Cap Value Fund

Researchers study how laser-induced ultrasound could help identify the stage of melanoma

Presence of SIBLING proteins in premalignant oral lesions may predict oral cancer

Researchers receive grant to study how ILD appears in patients with autoimmune diseases

Cephalon to acquire Ception Therapeutics following positive clinical study of eosinophilic asthma

Aradigm initiates dosing in Phase 2b trial of inhaled liposomal ciprofloxacin formulations in BE patients

Menssana Research develops 85% accurate breath test for pulmonary tuberculosis

Multidisciplinary rounds may facilitate implementation of best clinical practices: Study

FDA issues approval for Gileads's Cayston for respiratory symptoms in cystic fibrosis

Multidisciplinary, team-based approach can reduce mortality rates in ICUs

Lilly, Merck, Pfizer collaborate to accelerate research on commonly-diagnosed cancer

Belgian Hospital completes certification training for SynCardia's Total Artificial Heart implant

New cardiac imaging technique reduces radiation exposure compared to standard helical scan

Hospital-acquired infections increase mortality rate and healthcare costs

Black women are more prone to peripartum cardiomyopathy around childbirth time

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