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Natural extracellular vesicles containing ACE2 protein could fight new SARS-CoV-2 variants

Scientists at The University of Texas MD Anderson Cancer Center and Northwestern Medicine have identified natural extracellular vesicles containing the ACE2 protein (evACE2) in the blood of COVID-19 patients that can block infection from broad strains of SARS-CoV-2 virus in preclinical studies. The study was published today in Nature Communications.

20 Jan 2022

Development of a glycoprotein multi-epitope subunit vaccine candidate against South-African SARS-CoV-2 strains

In a new study, scientists focused on the SARS-CoV-2 Beta variant and used computational methods to design and develop effective glycoprotein multi-epitope subunit vaccine candidates, based on the old and the new Beta virus strains.

20 Jan 2022

Antibodies to SARS-CoV-2 and infection risk in healthcare workers following mRNA vaccination

A new study aimed to understand the risk of COVID-19 infection given certain serological parameters, in a group of vaccinated healthcare workers with high rates of exposure to the virus, followed up at 9 months from vaccination.

20 Jan 2022

Study finds Omicron infection effectively induces immunity against itself and enhances protection against other variants in vaccinated individuals

Researchers investigated the effectiveness of the SARS-CoV-2 Omicron-variant induced immunity, whether it is cross-protective against other variants, and if earlier infection with the SARS-CoV-2 Delta variant offers protection against Omicron.

20 Jan 2022

Exploring the potential utility of calcium channel inhibitors in SARS-CoV-2 infection

In a new study, researchers discuss the role of calcium signaling pathways as targets of inhibition in potential new antiviral therapeutic pathways for SARS-CoV-2.

20 Jan 2022

Virucidal effect of UV and violet light on SARS-CoV-2

In a recent study published in the Journal of Photochemistry and Photobiology, a team of researchers analyzed the effect of ultraviolet (UV) and violet light of different wavelengths on the virulence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

20 Jan 2022

Variants of SARS-CoV-2 and preventive strategies

A recent review article published in the journal Advanced Science reviewed the features of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and its variants. Using a physical and materials science perspective, the review also summarizes the most significant variants of SARS-CoV-2 encountered to date as well as possible preventive strategies.

19 Jan 2022

New findings could contribute to future therapeutics for muscle degeneration

An international team led by uOttawa Faculty of Medicine researchers have published findings that could contribute to future therapeutics for muscle degeneration due to old age, and diseases such as cancer and muscular dystrophy.

19 Jan 2022

Investigational cancer drug mimics the metabolic and therapeutic effects of fasting, mice study shows

An investigational cancer drug that starves tumors of their energy supply also shows evidence of improving whole body metabolism, according to a new study in mice from Washington University School of Medicine in St. Louis.

19 Jan 2022

Treatment with immune-boosting protein and radiation improves survival in mice with glioblastoma

Glioblastoma, an aggressive cancer in the brain or spinal cord, has proven stubbornly resistant to newer immunotherapies. And radiation and chemotherapy, the standard treatment for glioblastoma, result in fewer than 10% of patients surviving longer than five years after diagnosis.

19 Jan 2022

New mathematical model can calculate the risk of resistance evolution for drug pairs

Bacteria have dangerously evolved to thwart many of the medicines that were designed to kill them. As a result, a growing antibiotic resistance crisis is responsible for more than 700,000 deaths each year, emerging as one of the world's most pressing health issues.

19 Jan 2022

Novel antibody that targets the N-terminal domain of SARS-CoV-2 identified

A new study discusses the targeted discovery of NTD-reactive antibodies from an individual who had recovered from SARS-CoV-2 infection.

19 Jan 2022

Yale research sheds light on the lifespan and myriad functions of messenger RNAs

It took a global pandemic, but the critical role of messenger RNA in all of life's functions has taken center stage in the past year with the successful rollout of mRNA vaccines to combat the SARS-Cov-2 virus.

19 Jan 2022

New topical cream could help prevent frostbite injuries

Skiers, hikers, soldiers and others exposed to extreme cold temperatures can experience frostbite - a painful injury that occurs when ice crystals form in the skin. Many extremely cold areas are also remote, and delays in frostbite treatment can result in severe wounds, scarring and even limb amputation

19 Jan 2022

'Retinal age gap' can be an independent predictor of increased mortality risk

The difference between the biological age of the retina, the light sensitive layers of nerve tissue at the back of the eye, and a person's real (chronological) age, is linked to their risk of death, finds research published online in the British Journal of Ophthalmology.

19 Jan 2022

B Cell News and Research

Natural extracellular vesicles containing ACE2 protein could fight new SARS-CoV-2 variants

Development of a glycoprotein multi-epitope subunit vaccine candidate against South-African SARS-CoV-2 strains

Antibodies to SARS-CoV-2 and infection risk in healthcare workers following mRNA vaccination

Study finds Omicron infection effectively induces immunity against itself and enhances protection against other variants in vaccinated individuals

Exploring the potential utility of calcium channel inhibitors in SARS-CoV-2 infection

Virucidal effect of UV and violet light on SARS-CoV-2

Variants of SARS-CoV-2 and preventive strategies

New findings could contribute to future therapeutics for muscle degeneration

Investigational cancer drug mimics the metabolic and therapeutic effects of fasting, mice study shows

Treatment with immune-boosting protein and radiation improves survival in mice with glioblastoma

New mathematical model can calculate the risk of resistance evolution for drug pairs

Novel antibody that targets the N-terminal domain of SARS-CoV-2 identified

Yale research sheds light on the lifespan and myriad functions of messenger RNAs

New topical cream could help prevent frostbite injuries

'Retinal age gap' can be an independent predictor of increased mortality risk

Scientists reveal toxic astrocyte changes in ALS

Exploring biological characteristics of SARS-CoV-2-induced myocardial damage

Independent drug action responsible for greater clinical efficacy of combination cancer therapies

Study explores COVID-19 diagnosis and outcomes in HIV patients

Study reports of receptor-binding domain multimer capable of enhancing the immune response against SARS-CoV-2

Using single B cell screening to boost antibody discovery eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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