Infectious Diseases News and Research

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Biota and MedImmune announce clinical trial for respiratory syncytial virus antiviral drug

Biota Holdings Limited and MedImmune Inc. today announced the start of a Phase Ia clinical trial for their respiratory syncytial virus (RSV) antiviral drug, BTA9881, with the goal of providing a treatment for RSV-infected infants and adults.

17 Jul 2007

Latest in HIV/TB research

With HIV infection driving a deadly resurgence of tuberculosis (TB), a new publication provides up-to-date recommendations for clinicians facing the many challenges of treating patients with both of these two complex diseases.

17 Jul 2007

Myeloid-derived suppressor cells suppress anti-tumor response to cancer

Scientists at Johns Hopkins and elsewhere say they have mapped out an escape route that cancers use to evade the body's immune system, allowing the disease to spread unchecked.

17 Jul 2007

A challenge to the ancient origin of SIVagm based on African Green Monkey mitochondrial genomes

Monkey viruses related to HIV may have swept across Africa more recently than previously thought, according to new research from The University of Arizona in Tucson.

17 Jul 2007

Paint helps surgeons see where a tumor begins and ends

A tumor paint developed by researchers at Seattle Children's Hospital Research Institute and Fred Hutchinson Cancer Research Center will help surgeons see where a tumor begins and ends more precisely by illuminating the cancerous cells.

16 Jul 2007

Key mechanism to emergence of deadly strep bacteria discovered

The incidence of serious strep infections has risen dramatically in the last three decades, and this increase is largely attributed to the spread around the globe of a single strain of strep known as the invasive M1T1 clone.

16 Jul 2007

U.S. trial of new microbicide for HIV prevention to be tested in young women

Nearly half of all people infected with HIV/AIDS are now women, the majority of whom contracted the disease through sexual intercourse with male partners.

10 Jul 2007

MacroGenics investigational new drug for West Nile vrus monoclonal antibody is active

MacroGenics has announced that the company's investigational new drug (IND) application to the U.S. Food and Drug Administration for its monoclonal antibody targeted to West Nile Virus is now active.

10 Jul 2007

Number of new HIV cases in Sweden increases 40%

The number of new HIV cases recorded during the first half of this year in Sweden has increased 40% compared with the same time period last year and is at a record high, Xinhuanet reports.

10 Jul 2007

Etravirine reduces HIV viral loads when taken with Prezista

The experimental antiretroviral drug etravirine, made by Johnson & Johnson subsidiary Tibotec Pharmaceuticals, greatly reduces HIV viral loads in people with a history of drug resistance when taken in combination with Tibotec's antiretroviral Prezista, according to two studies published Saturday in the journal The Lancet.

10 Jul 2007

U.S. NIH funded trial of VivaGel in sexually active young women commences

Starpharma Holdings Limited today announced the commencement in the U.S. of a trial to assess the safety and acceptability of SPL7013 Gel (VivaGel) in sexually active young women.

9 Jul 2007

Ownership of genetic information

We all share our genetic make up with relatives, but should we also share ownership of the results of DNA analysis or should this knowledge be considered private?

9 Jul 2007

Autophagy may accelerate decompensated heart failure

Autophagy, a normal process by which cells eat their own proteins to provide needed resources to the body in times of stress, may paradoxically cause harm to hearts already weakened by disease, researchers from UT Southwestern Medical Center have found.

9 Jul 2007

How the HIV virus mutates to escape the body's immune system

A pioneering collaborative study has discovered how the HIV virus evades the human body's immune system.

9 Jul 2007

Include children in research to make breakthroughs in child medicine

Scientists will only make real breakthroughs in children's medicine if they include children in research programmes as well as adults, according to a leading paediatric expert.

9 Jul 2007

Chronic fatigue: clues in the blood

Researchers at the University of New South Wales (UNSW) believe that blood may hold vital insights into what is happening in the brain of patients with chronic fatigue syndrome (CFS).

8 Jul 2007

High cholesterol makes people more prone to tick disease human granulocytic anaplasmosis

People who have high cholesterol levels may be much more susceptible to a particular disease transmitted by the bites of ticks, a new study in mice suggests.

4 Jul 2007

Discovery of two effective antibodies for SARS

An international team of investigators has identified the first human antibodies that can neutralize different strains of the virus responsible for outbreaks of severe acute respiratory syndrome (SARS).

4 Jul 2007

Scientists tackle deadly hospital superbugs

It infiltrates hospitals as microscopic spores. Its defences are so strong it can resist most antibiotics. And it kills three times as many people every year as MRSA. But scientists at The University of Nottingham are amassing an arsenal of weapons in preparation for counter offensive against the most deadly of hospital superbugs.

4 Jul 2007

TB jetsetter not as dangerous as first thought

It seems the jet setting air traveller with tuberculosis (TB) is not quite as dangerous as first thought. According to a federal health official, American lawyer Andrew Speaker has a less severe form of TB than previously diagnosed.

4 Jul 2007