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Research could put penicillin back in battle against antibiotic resistant bugs

Research led by the University of Warwick has uncovered exactly how the bacterium Streptococcus pneumoniae has become resistant to the antibiotic penicillin.

13 Mar 2008

Simple laboratory test predicts risk of kidney injury after surgery

A simple laboratory test may provide a new way for doctors to identify patients at risk of developing potentially severe acute kidney injury (AKI) after surgery up to three days before the problem would otherwise be detected, reports a pilot study in the May 2008 issue of the Clinical Journal of the American Society of Nephrology.

13 Mar 2008

Increased level of magnetic iron oxides found in Alzheimer's disease

A team of scientists, led by Professor Jon Dobson, of Keele University in Staffordshire, UK, have found, for the first time, raised levels of magnetic iron oxides in the part of the brain affected by Alzheimer's Disease (AD).

13 Mar 2008

Good news for people with glycogen storage disease type Ia

A gene therapy treatment that restores a missing liver enzyme in test animals could provide a cure for a rare metabolic disorder in humans, according to Duke University Medical Center researchers.

13 Mar 2008

Genomics researchers fine-tune marker for common obesity gene

Genomics researchers, seeking to replicate another group's discovery of an important gene associated with obesity, have further refined the signal to a particular variant in DNA that may be more helpful in identifying this gene's role in obesity in various human populations worldwide.

13 Mar 2008

Study shows how nerve cells in visual cortex adapt to changing images

Neuroscientists studying the mind's ability to process images have completed the first empirical study to demonstrate, using animal models, how populations of nerve cells in visual cortex adapt to changing images.

13 Mar 2008

DNA detectives find genetic markers for lung cancers most likely to recur

Researchers at the Johns Hopkins Kimmel Cancer Center have uncovered clearly recognizable genetic alterations in tumors and tissue removed from patients with early-stage lung cancers that look like good predictors of which of these cancers are more likely to recur.

13 Mar 2008

Caspase-12: MUHC researcher finds new defense mechanism against intestinal inflammation

The body's first line of defence against pathogenic bacteria that we ingest may not be the immune system but rather the cells that line the intestine.

13 Mar 2008

New mouse model of bipolar disorder

Bipolar Disorder (BPD or manic-depressive illness) is one of the most serious of all mental disorders, affecting millions of individuals worldwide.

13 Mar 2008

New behavioral risk factors for head and neck cancers

Researchers at the Johns Hopkins Kimmel Cancer Center have teased out two distinct sets of risk factors for head and neck cancers, suggesting that there are two completely different kinds of the disease.

12 Mar 2008

Red-light cameras significantly increase crashes

Rather than improving motorist safety, red-light cameras significantly increase crashes and are a ticket to higher auto insurance premiums, researchers at the University of South Florida College of Public Health conclude.

12 Mar 2008

Blood test for Parkinson's shows promise

A test that profiles molecular biomarkers in blood could become the first accurate diagnostic test for Parkinson's disease, new research shows.

12 Mar 2008

Scientists discover epigenetic changes in schizophrenia and bipolar disorder

Scientists have discovered epigenetic changes (i.e. chemical changes to a gene that do not alter the DNA sequence) in individuals with schizophrenia and bipolar disorder.

12 Mar 2008

Researchers find treatment for familial cold autoinflammatory syndrome

Dalhousie Medical School dermatologist Dr. Barrie Ross and his colleagues have successfully ended a 20-year quest to find a treatment for Familial Cold Autoinflammatory Syndrome (FCAS).

12 Mar 2008

COX-2 expression is marker for cancer development in some benign breast biopsies

It's a good news, bad news situation. Some women who have a breast biopsy are told that while they don't have cancer, they do have atypical hyperplasia -- cells that aren't quite normal and might become cancerous someday.

12 Mar 2008

Scientists identify key protein in cell's 'self-eating' function

Molecular biologists at the University of California, San Diego have found one piece of the complex puzzle of autophagy, the process of "self-eating" performed by all eukaryotic cells - cells with a nucleus - to keep themselves healthy.

12 Mar 2008

Regenstrief Institute to tackle catastrophic disease outbreaks on behalf of CDC

The Centers for Disease Control has awarded the Indiana University School of Medicine a $2.6 million initial contract with the possibility of nearly $10 million in funding over 5 years to accelerate the real-time ability of local, state and regional entities to share data and information to enhance rapid response to and management of potentially catastrophic infectious disease outbreaks and other public health emergencies.

11 Mar 2008

Structure reveals how cells 'sugar-coat' proteins - process essential to many proteins' functions can lead to disease when gone awry

Biologists at the U.S. Department of Energy's Brookhaven National Laboratory, Stony Brook University, and the University of Wurzburg, Germany, have deciphered the structure of a large protein complex responsible for adding sugar molecules to newly formed proteins - a process essential to many proteins' functions.

11 Mar 2008

Adapting drug dosing to body size

University of Queensland researchers are leading the charge in adapting drug dosing to a society that is changing shape.

11 Mar 2008

Poor sleep more dangerous for women

Researchers at Duke University Medical Center say they may have figured out why poor sleep does more harm to cardiovascular health in women than in men.

11 Mar 2008