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City Of Hope builds cloud-based data commons platform for observational study

A $12 million federal grant enabled City of Hope and collaborators to deploy a novel cloud-computing platform, making an immense amount of data from a historic 25-year study more accessible and user-friendly.

5 Mar 2020

New type of adoptive cell therapy could target prostate and pancreatic cancers in humans

In experiments with mice, researchers at the Johns Hopkins Kimmel Cancer Center say they have slowed the growth of transplanted human prostate and pancreatic cancer cells by introducing bone marrow cells with a specific gene deletion to induce a novel immune response.

5 Mar 2020

Burden of colorectal cancer is rapidly shifting to younger individuals

The burden of colorectal cancer is swiftly shifting to younger individuals as incidence increases in young adults and declines in older age groups, according to the latest edition of Colorectal Cancer Statistics 2020, a publication of the American Cancer Society.

5 Mar 2020

New experimental platform for cancer diagnostics, prognoses and testing drugs

Parts of tumor tissue, which is normally discarded in cancer surgery, bear information about the disease. So far, as studies at the University of Gothenburg show, this has been unexploited.

4 Mar 2020

Inhibiting specific protein could make radiation therapy for colon cancer more effective

Researchers at Washington University School of Medicine in St. Louis appear to have discovered a way to make radiation therapy for colorectal cancer more effective by inhibiting a protein found in cancer cells in the gut.

3 Mar 2020

Density of immune cells could accurately predict survival in patients with stage III colon cancer

The density of immune cells, called tumor infiltrating lymphocytes, when combined with analysis of tumor budding may serve as a method to more accurately predict survival in patients with stage III colon cancer.

3 Mar 2020

Researchers develop multi-organ-on-a-chip for drug toxicity screening

Researchers in the US have developed a new multi-organ-on-a-chip to test how new drugs affect the human body's vital organs.

2 Mar 2020

New imaging method allows scientists to view key part of the colon in 3D

In a groundbreaking discovery, researchers at Children's Hospital of Philadelphia developed a new imaging method that allows scientists to view the enteric nervous system - a key part of the human colon - in three dimensions by making other colon cells that normally block it invisible.

27 Feb 2020

Cancer chemical from common gut microbe

Many common gut bacteria carry cancer-causing mutations, says a new study published in the journal Nature on the 27th February 2020.

27 Feb 2020

New method to deliver an immune system 'uncloaking' device directly to cancer cells

Scientists at Johns Hopkins report they have designed and successfully tested an experimental, super small package able to deliver molecular signals that tag implanted human cancer cells in mice and make them visible for destruction by the animals' immune systems.

26 Feb 2020

$Investigational drug reduces heartburn severity in patients with refractory GERD$

Investigational drug reduces heartburn severity in patients with refractory GERD

An investigational drug that binds bile acids in the stomach can reduce the severity of heartburn symptoms in patients with treatment-resistant gastroesophageal reflux disease (GERD) when combined with a proton pump inhibitor (PPI), a new study suggests.

26 Feb 2020

Ulcerative colitis and a missing microbe in the gut

Ulcerative colitis is a seriously debilitating inflammatory disease of the bowel leading to crippling symptoms that can affect the quality of life severely. Researchers from Stanford University School of Medicine have found in a new study that a missing microbe could be linked to this condition. The study was published today in the latest issue of the journal Cell Host & Microbe.

25 Feb 2020

Researchers study why colon cancer is more lethal in pediatric and young adult patients

Colon cancer is more likely to be lethal in children and young adults than middle-aged adults. In a single-institution study, researchers at The University of Texas MD Anderson Cancer Center, Houston, Tex., found that differences in mortality rates persist regardless of whether pediatric, adolescent, and young adult patients (aged 24 and younger) were born with a predisposition for colon abnormalities or disease and for the first time conclude that young people are more likely to have metastases outside the colon, into the abdominal cavity, when they are diagnosed.

23 Feb 2020

UCI makes tremendous strides in prevention, early detection and treatment of cancer

Like most people, John Gifford wasn't looking forward to a colonoscopy when he arrived on the UCI Medical Center campus in Orange in 2018.

23 Feb 2020

New Endothelial Cell Atlas can be used to improve treatments for many diseases

New surprising knowledge on endothelial cells in a dozen different murine tissues is now available in an open access, user-friendly, database for professionals.

20 Feb 2020

Racial disparities found in timing and type of treatment for colorectal cancer patients

In a new study published in Cancer Epidemiology, Associate Professor Dr. Cara Frankenfeld of the George Mason College of Health and Human Services found racial disparities in how the presence of cancer-related diagnostic and treatment technology is related to colorectal cancer patient outcomes in Georgia.

19 Feb 2020

Geriatric-specific characteristics linked to hospital readmission risk of elderly surgical patients

Researchers have examined new geriatric-specific characteristics that appear to raise the risk of elderly surgical patients having an unplanned hospital readmission within a month of initially leaving the hospital.

18 Feb 2020

Mediterranean diet promotes healthy aging with healthier gut microbiome

A new study published online in the journal Gut in February 2020 reports the striking health-promoting effects of switching to a Mediterranean diet for just one year. The results were due to an increase in the health and number of gut bacteria that favor a healthy diet.

17 Feb 2020

Scientists find a way to block the growth of kidney cancer

Scientists at the MDC have discovered stem cells responsible for the most common form of kidney cancer. The team of Walter Birchmeier has found a way to block the growth of these tumors in three models of the disease.

17 Feb 2020

Study provides a detailed molecular snapshot of endometrial cancer

A study published Feb. 13 in Cell provides an unprecedented look at the dozens of molecular steps that occur to bring about endometrial cancer, commonly known as uterine cancer.

14 Feb 2020

Colon News and Research

City Of Hope builds cloud-based data commons platform for observational study

New type of adoptive cell therapy could target prostate and pancreatic cancers in humans

Burden of colorectal cancer is rapidly shifting to younger individuals

New experimental platform for cancer diagnostics, prognoses and testing drugs

Inhibiting specific protein could make radiation therapy for colon cancer more effective

Density of immune cells could accurately predict survival in patients with stage III colon cancer

Researchers develop multi-organ-on-a-chip for drug toxicity screening

New imaging method allows scientists to view key part of the colon in 3D

Cancer chemical from common gut microbe

New method to deliver an immune system 'uncloaking' device directly to cancer cells

Investigational drug reduces heartburn severity in patients with refractory GERD

Ulcerative colitis and a missing microbe in the gut

Researchers study why colon cancer is more lethal in pediatric and young adult patients

UCI makes tremendous strides in prevention, early detection and treatment of cancer

New Endothelial Cell Atlas can be used to improve treatments for many diseases

Racial disparities found in timing and type of treatment for colorectal cancer patients

Geriatric-specific characteristics linked to hospital readmission risk of elderly surgical patients

Mediterranean diet promotes healthy aging with healthier gut microbiome

Scientists find a way to block the growth of kidney cancer

Study provides a detailed molecular snapshot of endometrial cancer

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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