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Replication of SARS-CoV-2 variants in different cell and organ models

In this study, the replication of B.1.1.7 viruses was analyzed in different cell and organ models and dwarf hamsters.

22 Oct 2021

Development of a safe and effective COVID-19 nanoparticle vaccine

Researchers from ReVacc scientific have attempted to demonstrate the effectiveness of a new vaccine, REVC-128, two weeks post-administration.

22 Oct 2021

Hydrogel-based vaccine delivery system evokes antibody response against SARS-CoV-2

Researchers from Stanford University have been attempting to create a hydrogel-based vaccine delivery system that could improve the immune response's strength and duration.

22 Oct 2021

Boosting nonhuman primates with Moderna vaccine increases neutralizing antibody responses

Boosting nonhuman primates with the Moderna vaccine (mRNA-1273) six months after their primary vaccine series increased neutralizing activity against viral variants of concern, a new study shows.

22 Oct 2021

SARS-CoV-2 cocktail with three antibodies potent in preclinical testing

Amidst growing concerns on the use and potential benefits of convalescent plasma therapy, a research group in the United States has identified three human antibodies (Abs) that, when combined, demonstrate both robust viral suppressive properties against all tested severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Variants of Concern (VoC) in vitro and profound antiviral efficacy in vivo.

22 Oct 2021

Broadly protective vaccines against coronaviruses needed to protect against future outbreaks

The coronavirus disease 2019 (COVID-19) pandemic, caused by the β-coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), alerted the world to the seriousness of the threat posed by novel viruses.

20 Oct 2021

New research on phagocytosis and SARS-CoV-2's spike protein

A new study showed that convalescent patient plasma and monoclonal anti-spike antibodies were able to induce phagocytosis at high antibody concentrations.

20 Oct 2021

Scientists search for cause of mysterious covid-related inflammation in children

Like most other kids with covid, Dante and Michael DeMaino seemed to have no serious symptoms.

20 Oct 2021

Suggested mechanism of SARS-CoV-2 infection inhibition by Mitoxantrone

A group of researchers performed a drug repurposing screen on an FDA-approved anti-cancer drug named Mitoxantrone.

20 Oct 2021

Long-term predictions of immunity after two doses of mRNA vaccine

Researchers from York University has investigated the long-term protection of two mRNA vaccines.

20 Oct 2021

BNT162b2 mRNA COVID-19 vaccine-induced antibodies wane over six month period

Researchers have been investigating the response of antibodies created against SARS-CoV-2 by the Pfizer-BioNTech six months after vaccination.

20 Oct 2021

Research may provide clues to how viral infections contribute to neurodegeneration

Some viral diseases could possibly contribute to neurodegeneration. DZNE researchers report this in the scientific journal "Nature Communications".

19 Oct 2021

Phase 2 trial shows COVID-19 recombinant protein vaccine elicits promising immunogenicity responses

Researchers performed a large-scale, double-blind, placebo-controlled phase two trial to assess the efficacy, safety, and immune response elicited from vaccination with MVC-COV1901.

19 Oct 2021

Structural mechanism of anti-SARS-CoV-2 neutralizing antibodies that target separate spike epitopes

Researchers from the Washington University School Of Medicine have identified how a subset of variants of concern can escape neutralization by two neutralizing antibodies.

19 Oct 2021

SARS-CoV-2 antibodies detected in breast milk of vaccinated mothers

Now, a new medRxiv* preprint study finds mothers vaccinated either one of the messenger RNA (mRNA) vaccines transferred neutralizing antibodies and cytokines, including interferon-gamma (IFNγ), to a breastfeeding child. Additionally, the humoral response in breastmilk was effective in neutralizing four variants of concern.

18 Oct 2021

Study shows enhanced immunogenicity of heterologous boosting strategy in individuals primed with J&J vaccine

Researchers from Singapore conducted a study to assess the spike protein-specific humoral and cellular immunity in Ad26.COV2.S vaccinated individuals either primed with Ad26.COV2.S only, or boosted with a homologous or heterologous second dose.

18 Oct 2021

How can framing COVID-19 vaccine side-effects affect an individual's willingness to be vaccinated?

Researchers from the University of Munich have investigated how framing vaccine side-effects can affect an individual's willingness to be vaccinated.

18 Oct 2021

Study assesses T-cell responses directed against highly conserved regions of SARS-CoV-2

The study aimed to assess whether highly conserved regions within coronaviruses harbor CD8+ T-cell epitopes, capable of being cross-recognized between different coronaviruses.

18 Oct 2021

Study provides the most detailed analysis of England's SARS-CoV-2 genomic surveillance information

The Covid-19 crisis that gripped the UK between September 2020 and June 2021 can be thought of as a series of overlapping epidemics, rather than a single event, say researchers at the Wellcome Sanger Institute, EMBL's European Bioinformatics Institute (EMBL-EBI) and their collaborators.

18 Oct 2021

Serologic testing algorithm to detect disparities in SARS-CoV-2 infection prevalence and vaccination uptake

A new study recently published on the medRxiv* preprint server demonstrates the use of a serological testing algorithm for identifying disparities in infection rates and vaccine uptake amongst the study population to enable public health interventions.

17 Oct 2021

Spike Protein News and Research

Replication of SARS-CoV-2 variants in different cell and organ models

Development of a safe and effective COVID-19 nanoparticle vaccine

Hydrogel-based vaccine delivery system evokes antibody response against SARS-CoV-2

Boosting nonhuman primates with Moderna vaccine increases neutralizing antibody responses

SARS-CoV-2 cocktail with three antibodies potent in preclinical testing

Broadly protective vaccines against coronaviruses needed to protect against future outbreaks

New research on phagocytosis and SARS-CoV-2's spike protein

Scientists search for cause of mysterious covid-related inflammation in children

Suggested mechanism of SARS-CoV-2 infection inhibition by Mitoxantrone

Long-term predictions of immunity after two doses of mRNA vaccine

BNT162b2 mRNA COVID-19 vaccine-induced antibodies wane over six month period

Research may provide clues to how viral infections contribute to neurodegeneration

Phase 2 trial shows COVID-19 recombinant protein vaccine elicits promising immunogenicity responses

Structural mechanism of anti-SARS-CoV-2 neutralizing antibodies that target separate spike epitopes

SARS-CoV-2 antibodies detected in breast milk of vaccinated mothers

Study shows enhanced immunogenicity of heterologous boosting strategy in individuals primed with J&J vaccine

How can framing COVID-19 vaccine side-effects affect an individual's willingness to be vaccinated?

Study assesses T-cell responses directed against highly conserved regions of SARS-CoV-2

Study provides the most detailed analysis of England's SARS-CoV-2 genomic surveillance information

Serologic testing algorithm to detect disparities in SARS-CoV-2 infection prevalence and vaccination uptake

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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