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New technology developed to track position of nanoparticles within the body or inside a cell

A long-sought goal of creating particles that can emit a colorful fluorescent glow in a biological environment, and that could be precisely manipulated into position within living cells, has been achieved by a team of researchers at MIT and several other institutions. The finding is reported this week in the journal Nature Communications.

10 Oct 2014

Columbia University's imaging software gets FDA 510k clearance

Columbia University's imaging software that facilitates 3-D lung tumor segmentation, licensed to Varian Medical Systems, has been incorporated into the Smart Segmentation module of Varian's Eclipse treatment planning system and has received FDA 510k clearance.

10 Oct 2014

RNA molecules in tissue, urine samples can detect prostate cancer

Researchers at Sanford-Burnham Medical Research Institute have identified a set of RNA molecules that are detectable in tissue samples and urine of prostate cancer patients but not in normal healthy individuals.

10 Oct 2014

Study addresses the challenge of genomic heterogeneity

Known cancer-driving genomic aberrations in localized lung cancer appear to be so consistently present across tumors that a single biopsy of one region of the tumor is likely to identify most of them, according to a paper published today in Science.

10 Oct 2014

Chronic contact allergy from metal orthopedic implant linked to aggressive form of skin cancer

In rare cases, patients with allergies to metals develop persistent skin rashes after metal devices are implanted near the skin. New research suggests these patients may be at increased risk of an unusual and aggressive form of skin cancer.

10 Oct 2014

CTCs in blood of metastatic cancer patients give genomic read-out of breast cancer

The genetic fingerprint of a metastatic cancer is constantly changing, which means that the therapy that may have stopped a patient's cancer growth today, won't necessarily work tomorrow.

9 Oct 2014

VAL-083 drug compound shows promise against non-small cell lung cancer

DelMar Pharmaceuticals, Inc., a clinical-stage oncology company, today announced the presentation of promising new data supporting the activity of its lead drug compound, VAL-083, in the treatment of non-small cell lung cancer (NSCLC) at the AACR's New Horizons in Cancer Research: Harnessing Breakthroughs – Targeting Cures. The conference takes place October 9th to 12th in Pudong, Shanghai.

9 Oct 2014

HemoShear completes first-phase development of novel cancer drug discovery platform

HemoShear today announced that it has completed the first phase of development of a novel cancer drug discovery platform that replicates human tumor biology and responds to clinically-relevant drug concentrations.

9 Oct 2014

CytRx begins Phase 1b trial of aldoxorubicin plus gemcitabine in patients with metastatic solid tumors

CytRx Corporation, a biopharmaceutical research and development company specializing in oncology, today announced the initiation of enrollment in an open-label Phase 1b clinical trial designed to investigate the preliminary safety and activity of aldoxorubicin plus gemcitabine in subjects with metastatic solid tumors.

9 Oct 2014

University of Luxembourg researchers identify potential new ways to test colorectal cancer

Researchers at the University of Luxembourg have identified potential new ways to test for the first signs of one of the most deadly types of cancer: colorectal cancer. They have found new "biomarkers": molecules whose increased presence or absence in tissue suggests the development of tumorous cells. These indicators could help detect colorectal cancer at an early stage, predict its severity or even offer new treatments.

9 Oct 2014

NIH announces high-risk, high-reward grants for UCSF researchers

UC San Francisco researchers received five awards announced this week by the National Institutes of Health (NIH) for high-risk, high-reward scientific research projects. Their work will focus on novel approaches for diagnosing and treating diseases ranging from autoimmune and chronic inflammatory diseases, to cancer, diabetes and neurological disorders.

8 Oct 2014

MicroRNA molecule plays crucial role in managing cell survival and growth

Researchers at the University of California, San Diego School of Medicine have identified a microRNA molecule as a surprisingly crucial player in managing cell survival and growth.

8 Oct 2014

GenomOncology, med fusion partner to optimize treatment strategies for tumor

med fusion, an integrated molecular center of excellence and clinical trials service organization and GenomOncology, an Ohio based genomics technology and services provider, today announced a partnership to optimize treatment strategies based on the patient's disease state and tumor profile.

8 Oct 2014

Tel Aviv University researcher advances novel strategy to fight cancer by shoring up the immune system

Two years ago, Prof. Eshel Ben-Jacob of Tel Aviv University's School of Physics and Astronomy and Rice University's Center for Theoretical Biological Physics made the startling discovery that cancer, like an enemy hacker in cyberspace, targets the body's communication network to inflict widespread damage on the entire system.

8 Oct 2014

UCSD researchers define epidemiology of gastrointestinal stromal tumors

Researchers at the University of California, San Diego School of Medicine have, for the first time, clearly defined the epidemiology of gastrointestinal stromal tumors (GIST), which occur primarily in the lining of the stomach and small intestine.

8 Oct 2014

Lung cancer can be detected much earlier using lab-on-a-chip technology

Scientists have been laboring to detect cancer and a host of other diseases in people using promising new biomarkers called "exosomes." Indeed, Popular Science magazine named exosome-based cancer diagnostics one of the 20 breakthroughs that will shape the world this year. Exosomes could lead to less invasive, earlier detection of cancer, and sharply boost patients' odds of survival.

8 Oct 2014

'Achilles heel' in metabolic pathway could stop growth of lung cancer cells

Researchers at UT Southwestern Medical Center have found an "Achilles heel" in a metabolic pathway crucial to stopping the growth of lung cancer cells.

8 Oct 2014

UCSF researchers receive five NIH awards for high-risk scientific research projects

UC San Francisco researchers received five awards announced this week by the National Institutes of Health for high-risk, high-reward scientific research projects. Their work will focus on novel approaches for diagnosing and treating diseases ranging from autoimmune and chronic inflammatory diseases, to cancer, diabetes and neurological disorders.

8 Oct 2014

NF-kB molecule may help malignant cells hide from the immune system

A molecule that helps cancer cells evade programmed self-destruction, an internal source of death, might also help malignant cells hide from the immune system, an external source of death.

8 Oct 2014

Avidity NanoMedicines closes $6M convertible note financing, expands investor syndicate

Avidity NanoMedicines today announced that it has expanded its investor syndicate through the closing of a $6 million convertible note financing co-led by Fidelity Biosciences and TPG Biotech.

7 Oct 2014

Tumor News and Research

New technology developed to track position of nanoparticles within the body or inside a cell

Columbia University's imaging software gets FDA 510k clearance

RNA molecules in tissue, urine samples can detect prostate cancer

Study addresses the challenge of genomic heterogeneity

Chronic contact allergy from metal orthopedic implant linked to aggressive form of skin cancer

CTCs in blood of metastatic cancer patients give genomic read-out of breast cancer

VAL-083 drug compound shows promise against non-small cell lung cancer

HemoShear completes first-phase development of novel cancer drug discovery platform

CytRx begins Phase 1b trial of aldoxorubicin plus gemcitabine in patients with metastatic solid tumors

University of Luxembourg researchers identify potential new ways to test colorectal cancer

NIH announces high-risk, high-reward grants for UCSF researchers

MicroRNA molecule plays crucial role in managing cell survival and growth

GenomOncology, med fusion partner to optimize treatment strategies for tumor

Tel Aviv University researcher advances novel strategy to fight cancer by shoring up the immune system

UCSD researchers define epidemiology of gastrointestinal stromal tumors

Lung cancer can be detected much earlier using lab-on-a-chip technology

'Achilles heel' in metabolic pathway could stop growth of lung cancer cells

UCSF researchers receive five NIH awards for high-risk scientific research projects

NF-kB molecule may help malignant cells hide from the immune system

Avidity NanoMedicines closes $6M convertible note financing, expands investor syndicate

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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