Inflammation News and Research

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Animal study suggests ibuprofen can reduce lung inflammation in elderly

New research shows that the lungs become more inflammatory with age and that ibuprofen can lower that inflammation.

3 Oct 2014

Taking NSAIDs with other drugs can increase risk of upper GI bleeding, study finds

Nonsteroidal anti-inflammatory drugs (NSAIDs) - such as ibuprofen and aspirin - increase one's risk of upper gastrointestinal bleeding. When taken in combination with other drugs, this risk is significantly higher, according to new research appearing in the October issue of Gastroenterology, the official journal of the American Gastroenterological Association.

3 Oct 2014

NKT Therapeutics' NKTT120 receives FDA Fast Track designation for treatment of sickle cell disease

NKT Therapeutics today announced that the U.S. Food and Drug Administration has granted Fast Track designation to NKTT120, the company's lead therapeutic being developed for the treatment of sickle cell disease.

3 Oct 2014

Allakos secures additional $10M investment to expand its development portfolio

Allakos Inc. announced today that it has secured an additional $10 million investment from current investors to fund development of an additional therapeutic antibody.

30 Sep 2014

Research: Gut bacteria may cause animals to gain weight

A species of gut bacteria called Clostridium ramosum, coupled with a high-fat diet, may cause animals to gain weight. The work is published this week in mBio-, the online open-access journal of the American Society for Microbiology.

30 Sep 2014

Nondigestible compounds in apples may help prevent obesity-related disorders

Scientists at Washington State University have concluded that nondigestible compounds in apples - specifically, Granny Smith apples - may help prevent disorders associated with obesity. The study, thought to be the first to assess these compounds in apple cultivars grown in the Pacific Northwest, appears in October's print edition of the journal Food Chemistry.

30 Sep 2014

Bausch + Lomb’s sub-micron loteprednol etabonate ophthalmic gel meets primary endpoint

Bausch + Lomb, a wholly owned subsidiary of Valeant Pharmaceuticals International, Inc. (NYSE: VRX and TSX: VRX), today announced that its next generation sub-micron gel formulation of loteprednol etabonate was statistically superior to placebo (vehicle gel) in eliminating inflammation and pain following cataract surgery by study day eight, the primary endpoints in the first Phase 3, multi-center, double-masked, vehicle-controlled, parallel-group study.

30 Sep 2014

Early detection of cancers on the horizon with supersensitive nanodevice

Extremely early detection of cancers and other diseases is on the horizon with a supersensitive nanodevice being developed at The University of Alabama in Huntsville in collaboration with The Joint School of Nanoscience and Nanoengineering in Greensboro, NC.

29 Sep 2014

Fecal microbiota transplantation officially recommended for effective treatment of C. difficile infection

The transplantation of faecal microbiota from a healthy donor has been shown in recent clinical studies to be a safe and highly effective treatment for recurrent Clostridium difficile (C. difficile) infection and is now recommended in European treatment guidelines.

29 Sep 2014

Mild autumn could bring more misery for hayfever sufferers

Researchers at the University of Leicester have recorded a rare type of pollen that is a potent trigger of hayfever and asthma symptoms at record levels for the first time in four decades.

29 Sep 2014

Weight cycling linked to relapse-prone bipolar course

Patients with bipolar disorder are more likely than healthy controls to have a history of weight cycling, which in turn is associated with an increased likelihood of manic and depressive episodes, researchers report.

25 Sep 2014

NIH awards grants to 11 research groups to establish AMP RA/Lupus Network

The National Institutes of Health has awarded grants to 11 research groups across the United States to establish the Accelerating Medicines Partnership in Rheumatoid Arthritis and Lupus (AMP RA/Lupus) Network.

25 Sep 2014

New findings raise hope for novel class of drugs to treat lupus

New findings by a biomedical engineer and his team at the University of Houston raise hope for a new class of drugs to treat lupus that may not include the long list of adverse risks and side effects often associated with current treatments for this disease.

25 Sep 2014

Blocking AEG-1 gene expression halts development of liver cancer by regulating inflammation

Inflammation has been shown to be a driving force behind many chronic diseases, especially liver cancer, which often develops due to chronic inflammation caused by conditions such as viral hepatitis or alcoholism and has relatively few effective treatment options.

23 Sep 2014

Researchers say that environment plays much stronger role than genetics in eosinophilic esophagitis

Researchers have found that environment has a much stronger role than genetics in eosinophilic esophagitis (EoE), a severe, often painful food allergy that renders children unable to eat a wide variety of foods.

23 Sep 2014

Caltech researcher explores link between variable heart rate, health and fitness

Although the heart beats out a very familiar "lub-dub" pattern that speeds up or slows down as our activity increases or decreases, the pattern itself isn't as regular as you might think. In fact, the amount of time between heartbeats can vary even at a "constant" heart rate-and that variability, doctors have found, is a good thing.

23 Sep 2014

Brandeis researchers explore relationship between weight and stress-induced inflammation

If you're overweight, you may be at greater risk for stress-related diseases like type 2 diabetes, cardiovascular disease and cancer, according to a new study by Brandeis University.

22 Sep 2014

Sequencing the Asian liver fluke genome: an interview with Dr Neil Young

Opisthorchis viverrini is a parasitic flatworm (or liver fluke) endemic throughout Thailand, the Lao People’s Democratic Republic, Vietnam and Cambodia. Humans are infected with this parasite when they eat a fluke encysted in inadequately cooked/preserved freshwater fish.

21 Sep 2014

SLU pediatric researcher to study efficacy of new hepatitis C drug treatment in children

After the success of a new drug treatment in adults with hepatitis C infection, a Saint Louis University pediatric researcher is testing the safety and efficacy of the medications in children.

21 Sep 2014

Soligenix awarded $24.7 million contract to advance development of Rivax vaccine

Soligenix, Inc., a late-stage biopharmaceutical company developing products that address unmet medical needs in the areas of inflammation, oncology and biodefense, announced today that it has been awarded a contract valued at up to $24.7 million inclusive of options by the US Department of Health and Human Service's National Institutes of Health (specifically funded by the National Institute of Allergy and Infectious Diseases or NIAID).

19 Sep 2014

Inflammation News and Research

Animal study suggests ibuprofen can reduce lung inflammation in elderly

Taking NSAIDs with other drugs can increase risk of upper GI bleeding, study finds

NKT Therapeutics' NKTT120 receives FDA Fast Track designation for treatment of sickle cell disease

Allakos secures additional $10M investment to expand its development portfolio

Research: Gut bacteria may cause animals to gain weight

Nondigestible compounds in apples may help prevent obesity-related disorders

Bausch + Lomb’s sub-micron loteprednol etabonate ophthalmic gel meets primary endpoint

Early detection of cancers on the horizon with supersensitive nanodevice

Fecal microbiota transplantation officially recommended for effective treatment of C. difficile infection

Mild autumn could bring more misery for hayfever sufferers

Weight cycling linked to relapse-prone bipolar course

NIH awards grants to 11 research groups to establish AMP RA/Lupus Network

New findings raise hope for novel class of drugs to treat lupus

Blocking AEG-1 gene expression halts development of liver cancer by regulating inflammation

Researchers say that environment plays much stronger role than genetics in eosinophilic esophagitis

Caltech researcher explores link between variable heart rate, health and fitness

Brandeis researchers explore relationship between weight and stress-induced inflammation

Sequencing the Asian liver fluke genome: an interview with Dr Neil Young

SLU pediatric researcher to study efficacy of new hepatitis C drug treatment in children

Soligenix awarded $24.7 million contract to advance development of Rivax vaccine

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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