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Synthetic, Enterome partner to study effects of beta-lactam antibiotics on gastrointestinal microflora

Synthetic Biologics, Inc., a developer of novel anti-infective biologic and drug candidates targeting specific pathogens that cause serious infections and diseases, and Enterome Bioscience SA, a pioneer in the development of innovative disease management solutions based on a deep understanding of the gut microbiome, today announced that they have entered into an agreement to conduct metagenomic research on the effects of beta-lactam antibiotics on the gastrointestinal microflora (microbiome) of human patients.

10 Jun 2014

Research finding paves way for targeted approaches to treating cancer patients

Twelve years ago, UNC School of Medicine researcher Brian Strahl, PhD, found that a protein called Set2 plays a role in how yeast genes are expressed - specifically how DNA gets transcribed into messenger RNA. Now his lab has found that Set2 is also a major player in DNA repair, a complicated and crucial process that can lead to the development of cancer cells if the repair goes wrong.

9 Jun 2014

Scientists develop new molecule for monitoring drug concentration

Monitoring the drug concentration in patients is critical for effective treatment, especially in cases of cancer, heart disease, epilepsy and immunosuppression after organ transplants.

9 Jun 2014

New process to help select personalized treatment options for patients with lung adenocarcinoma

Moffitt Cancer Center researchers, in collaboration with the Lung Cancer Mutation Consortium, have developed a process to analyze mutated genes in lung adenocarcinoma to help better select personalized treatment options for patients.

4 Jun 2014

Men create more new proteins than women during interval training

When it comes to reaping benefits of sprint interval training, it appears that men have won the battle of the sexes, if just barely. According to new research published in the June 2014 issue of The FASEB Journal, men create more new proteins as a result of this exercise than women do.

3 Jun 2014

CHLA researchers develop novel NextGen sequencing approach for retinoblastoma

Researchers at Children's Hospital Los Angeles have developed a unique next-generation sequencing test for the gene linked to retinoblastoma. The new approach is both more comprehensive and can be conducted in less time than existing tests - enabling early detection of the cancer's genetic cause, which is critical for optimal treatment outcomes.

3 Jun 2014

Researchers create experimental blood test that determines BHI by gauging performance of mitochondria

Researchers at the University of Alabama at Birmingham School of Medicine have created an experimental blood test that, for the first time, determines a "Bioenergetic Health Index," or BHI, by gauging the performance of mitochondria, the cell's energy powerhouses.

30 May 2014

Blood gene expression profile identifies patients with elevated risk of cardiovascular death

A study of 338 patients with coronary artery disease has identified a gene expression profile associated with an elevated risk of cardiovascular death. Used with other indicators such as biochemical markers and family history, the profile - based on a simple blood test - may help identify patients who could benefit from personalized treatment and counseling designed to address risk factors.

30 May 2014

Transgenomic signs license with Dana-Farber to develop multiplexed ICE COLD-PCR technology

Transgenomic, Inc., a global biotechnology company advancing personalized medicine in cardiology, oncology, and inherited diseases through advanced diagnostic tests and clinical and research services, today announced that it has signed a license with the Dana-Farber Cancer Institute for worldwide rights to develop and commercialize multiplexed versions of its ICE COLD-PCRTM technology (MX ICE COLD-PCR).

28 May 2014

Immucor's PreciseType HEA test receives FDA approval to predict blood compatibility

Immucor, Inc., a global leader in transfusion and transplantation diagnostics, announced that the U.S. Food and Drug Administration has granted approval for the company's PreciseType HEA test.

23 May 2014

Researchers identify mutation in fat-storage gene that appears to increase risk for type 2 diabetes

Researchers at the University of Maryland School of Medicine have identified a mutation in a fat-storage gene that appears to increase the risk for type 2 diabetes and other metabolic disorders, according to a study published online today in the New England Journal of Medicine.

23 May 2014

Researchers use computer simulations to identify drugs most likely to kill cancer cells

Researchers at University of California, San Diego School of Medicine and Moores Cancer Center have used computer simulations of cancer cells - cancer avatars - to identify drugs most likely to kill cancer cells isolated from patients' brain tumors.

22 May 2014

$Fracture liaison service reduces risk of fragility fractures in older adults$

Fracture liaison service reduces risk of fragility fractures in older adults

Studies have shown that anyone age 50 or older who suffers a fragility fracture – a bone break sustained in a fall from a standing height or less – is two to five times more likely to experience a second fracture than someone who hasn't had one. The odds that a person who's suffered two such fractures will have a third are even higher.

17 May 2014

Viewpoints: GOP attacks on health law; challenging assumptions about Obamacare politics; is employer mandate worth it?

A crucial component of the Republican Party's assault on the Affordable Care Act always has been ignorance -- that is, the promotion of ignorance about the ACA's benefits among the general population. Now, from the consulting firm McKinsey & Co., comes hard evidence that the campaign worked, bigtime. In its latest national survey to determine how the healthcare reform act has been working, McKinsey found that the perceived cost of health insurance still was the No. 1 reason given by respondents for not enrolling (Michael Hiltzik, 5/14).

16 May 2014

Personalized Medicine News and Research

Synthetic, Enterome partner to study effects of beta-lactam antibiotics on gastrointestinal microflora

Research finding paves way for targeted approaches to treating cancer patients

Scientists develop new molecule for monitoring drug concentration

New process to help select personalized treatment options for patients with lung adenocarcinoma

Men create more new proteins than women during interval training

CHLA researchers develop novel NextGen sequencing approach for retinoblastoma

Researchers create experimental blood test that determines BHI by gauging performance of mitochondria

Blood gene expression profile identifies patients with elevated risk of cardiovascular death

Transgenomic signs license with Dana-Farber to develop multiplexed ICE COLD-PCR technology

Immucor's PreciseType HEA test receives FDA approval to predict blood compatibility

Researchers identify mutation in fat-storage gene that appears to increase risk for type 2 diabetes

Researchers use computer simulations to identify drugs most likely to kill cancer cells

Fracture liaison service reduces risk of fragility fractures in older adults

Viewpoints: GOP attacks on health law; challenging assumptions about Obamacare politics; is employer mandate worth it?

Researchers test genomic sequencing for women with triple negative breast cancer

Virtualscopics reports record revenues in first quarter 2014

NSHOA and Caris Life Sciences collaborate to establish personalized cancer care program

Flatiron Health agrees to acquire Altos Solutions

Leica and Affymetrix launch fully automated RNA in situ hybridization assays

Molecular subtyping provides insights into how to treat breast cancer

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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