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Antibodies to SARS-CoV-2 spike protein and RBD detected in saliva of mRNA-vaccine recipients

A team of researchers from the US and the Netherlands recently reported that antibodies to the spike protein and the RBD are detected in saliva samples from healthcare workers vaccinated with mRNA vaccines.

12 Mar 2021

Pooling COVID-19 tests to detect future outbreaks

How could pooling SARS-CoV-2 tests help to detect future viral outbreaks? News-Medical spoke to Dr. Jean-François Rupprecht to find out more.

12 Mar 2021

Study shows how functional biomaterials rely on interfacial protein layer to transmit signals to living cells

An interdisciplinary research team at Lehigh University has unraveled how functional biomaterials rely upon an interfacial protein layer to transmit signals to living cells concerning their adhesion, proliferation and overall development

12 Mar 2021

SARS-CoV-2 can infect blood monocytes and trigger inflammation, finds study

Researchers found about 10% of blood monocytes in coronavirus disease 2019 (COVID-19) patients are infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). These monocytes then die, leading to the release of cytokines – a feature associated with severe and critical COVID-19.

11 Mar 2021

NYITCOM researcher secures NSF CAREER award to study brain-skull interactions

Akinobu "Aki" Watanabe, Ph.D., assistant professor of anatomy at New York Institute of Technology College of Osteopathic Medicine (NYITCOM), has secured a prestigious Faculty Early Career Development Program award from the U.S. National Science Foundation.

10 Mar 2021

Organ-on-chip consortium receives huge grant to develop a universal standard for pharmaceutical industry

Scientists are pushing ahead building 'organ-on-chips', small chips with human cells, which are useful, for example, for studying cancerous metastases in the bloodstream or the development of scar tissue, or for testing the effect of drugs or food outside a human body.

10 Mar 2021

Adjustable tip spacing pipettes – the best ally for repetitive tasks in cancer research

Reproducibility of results and high throughput are crucial goals for many molecular biology labs, but it can be challenging to achieve these together without appropriate instrumentation. This creates a need for reliable instruments to minimize user error and perform accurate measurements consistently for numerous samples.

From INTEGRA Biosciences 9 Mar 2021

Speaking whilst infected with COVID-19 may cause it to spread

News-Medical speaks to Dr. Keiko Ishii about her research efforts during the COVID-19 pandemic and how speaking whilst infected can cause the virus to spread, and why wearing masks is so important.

9 Mar 2021

A SARS-CoV-2 spike protein adjuvant vaccine candidate produces durable rapid protection in vivo

A recent study reports the safety and high efficacy of an adjuvanted vaccine candidate against SARS-CoV-2 and the complications of COVID-19.

5 Mar 2021

Micro-Doppler radars could soon be used to predict injury risk and track recovery

Micro-Doppler radars could soon be used in clinical settings to predict injury risk and track recovery progress, according to Penn State researchers.

4 Mar 2021

Results from phase 2 trial of Novavax recombinant nanoparticle SARS-CoV-2 vaccine

Novavax, Inc., the American vaccine development company, has been developing a recombinant protein nanoparticle COVID-19 vaccine currently termed NVX-CoV2373. The full-length spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is created in a baculovirus vector, which is then inserted into a lipid nanoparticle around 50 nm in diameter.

3 Mar 2021

UTHSC researchers awarded $1.9 million to study white matter mechanisms underlying dementia

The National Institute of Neurological Disorders and Stroke has awarded two UTHSC researchers over $1.9 million to study the pathogenesis of white matter damage, a main contributing factor to dementia.

3 Mar 2021

Researchers develop ultrapotent miniproteins that target SARS-CoV-2 receptor-binding domain

Researchers have investigated the effectiveness of a bioengineered miniprotein in protecting against SARS-CoV-2 infection in vivo. The researchers evaluated the miniprotein, LCB1, against SARS-CoV-2-mediated lung disease in human ACE2-expressing transgenic mice.

3 Mar 2021

The benefits and risks of using online health forums and services

The internet provides a major source of exchanging health information through online portals and new media. Internet users can access health sites and online forums to obtain health information.

2 Mar 2021

Comparative analysis of SARS-CoV-2 antivirals leads to new potential treatment for COVID-19

Scientists compared the in vitro efficacy and cytotoxicity profiles of PF-00835231 and remdesivir in two human model systems for SARS-CoV-2 infection.

1 Mar 2021

Inhalable nanobody shows potent anti-SARS-CoV-2 activity in vivo

Researchers have developed a stable and ultrapotent homotrimeric Pittsburgh inhalable Nanobody 21 (PiN-21) against SARS-CoV-2 infection in Syrian hamsters. They demonstrated the high therapeutic efficacy of this homotrimeric Nb, leveraging both intranasal and aerosol delivery.

26 Feb 2021

Borosilicate Glass Microplates Improve Imaging Sensitivity

Porvair Sciences new Krystal™ Glass Bottom microplate with high quality specialty glass from Schott provides unmatched performance for whole-plate CCD imaging and laser detection applications.

From Chromatrap® - Porvair Sciences Ltd 26 Feb 2021

SNX-5422 could make an effective COVID-19 prophylactic, says study

SNX-5422 is a heat shock protein 90 (Hsp90) inhibitor currently undergoing clinical trials as a cancer therapeutic. A recent study examines the applicability of repurposing the drug towards severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) replication inhibition.

25 Feb 2021

Study reports lasting immune response in convalescent COVID-19 patients

Researchers report the cellular immune response of convalescent patients in Germany, who recovered from mild or moderate infection compared to that of healthy people with no history of COVID-19.

25 Feb 2021

Novel single-particle digital assay using plasmonic nanobubbles

An interdisciplinary team from the University of Texas applied DIAMOND to the respiratory syncytial virus (RSV) diagnostics and demonstrated that DIAMOND is 150 times more sensitive than commercial lateral flow assays. They found that the measurements are completed within 2 minutes. The results of this study are published on the medRxiv* preprint server.

25 Feb 2021

micro News and Research

Antibodies to SARS-CoV-2 spike protein and RBD detected in saliva of mRNA-vaccine recipients

Pooling COVID-19 tests to detect future outbreaks

Study shows how functional biomaterials rely on interfacial protein layer to transmit signals to living cells

SARS-CoV-2 can infect blood monocytes and trigger inflammation, finds study

NYITCOM researcher secures NSF CAREER award to study brain-skull interactions

Organ-on-chip consortium receives huge grant to develop a universal standard for pharmaceutical industry

Adjustable tip spacing pipettes – the best ally for repetitive tasks in cancer research

Speaking whilst infected with COVID-19 may cause it to spread

A SARS-CoV-2 spike protein adjuvant vaccine candidate produces durable rapid protection in vivo

Micro-Doppler radars could soon be used to predict injury risk and track recovery

Results from phase 2 trial of Novavax recombinant nanoparticle SARS-CoV-2 vaccine

UTHSC researchers awarded $1.9 million to study white matter mechanisms underlying dementia

Researchers develop ultrapotent miniproteins that target SARS-CoV-2 receptor-binding domain

The benefits and risks of using online health forums and services

Comparative analysis of SARS-CoV-2 antivirals leads to new potential treatment for COVID-19

Inhalable nanobody shows potent anti-SARS-CoV-2 activity in vivo

Borosilicate Glass Microplates Improve Imaging Sensitivity

SNX-5422 could make an effective COVID-19 prophylactic, says study

Study reports lasting immune response in convalescent COVID-19 patients

Novel single-particle digital assay using plasmonic nanobubbles

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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