Therapy News and Research

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TWILIGHT trial: Brilinta reduces bleeding compared to dual therapy in high-risk coronary patients

Results from two subgroup analyses of the Phase IV independent TWILIGHT trial funded by AstraZeneca showed Brilinta (ticagrelor) monotherapy reduced the risk of clinically relevant bleeding over 12 months compared to aspirin plus Brilinta in high-risk coronary patients.

From AstraZeneca 30 Mar 2020

Research shows significant difference in radiation response between sexes

Women undergoing radiotherapy for many cancers are more likely than men to be cured, but the side effects are more brutal, according to one of Australia's most experienced radiation oncology medical physicists.

30 Mar 2020

'Living drug factories' could be used to achieve long-term treatment of chronic diseases

One promising way to treat diabetes is with transplanted islet cells that produce insulin when blood sugar levels get too low.

30 Mar 2020

Monoclonal antibody reduces LDL cholesterol in adult patients with HoFH

The cholesterol drug alirocumab reduced low-density lipoprotein (LDL) cholesterol by 35.6% compared to placebo in adult patients with homozygous familial hypercholesterolemia (HoFH), according to a phase three clinical trial presented at the American College of Cardiology's Annual Scientific Session Together with World Congress of Cardiology.

30 Mar 2020

Mount Sinai researchers figure out how to ramp up immune system to prevent tumor growth

Mount Sinai researchers have discovered a pathway that regulates special immune system cells in lung cancer tumors, suppressing them and allowing tumors to grow.

30 Mar 2020

Houston Methodist receives FDA approval to transfuse donated plasma into a COVID-19 patient

Houston Methodist received FDA approval Saturday to become the first academic medical center in the nation to transfuse donated plasma from a recovered COVID-19 patient into a critically ill patient.

30 Mar 2020

Low-dose rivaroxaban reduces adverse heart events in symptomatic PAD post-intervention

People with symptomatic peripheral artery disease who took the blood thinner rivaroxaban with aspirin after undergoing a procedure to treat blocked arteries in the leg (lower extremity revascularization) had a 15% reduction in the risk of major adverse limb and cardiovascular events when compared with those receiving aspirin alone, according to research presented at the American College of Cardiology's Annual Scientific Session Together with World Congress of Cardiology.

30 Mar 2020

Researchers develop a 'cardiac patch with bioink' to repair the heart

The heart is the driving force of circulating blood in the body and pumps blood to the entire body by repeating contraction and relaxation of the heart muscles continuously.

30 Mar 2020

Research could open up new therapeutic strategies for some lung and kidney cancers

New findings from researchers at The University of Texas MD Anderson Cancer Center about how some cancer cells become "addicted" to glucose could open up fresh approaches to therapy strategies for cancers with high levels of an amino acid transporter called solute carrier family 7 member 11 (SLC7A11).

30 Mar 2020

Revita DMR therapy has potential to transform lives of patients with poorly controlled type 2 diabetes

Patients with poorly controlled type 2 diabetes who underwent a novel, minimally invasive, endoscopic procedure called Revita duodenal mucosal resurfacing had significantly improved blood glucose (sugar) levels, liver insulin sensitivity, and other metabolic measures three months later, according to new data from the REVITA-2 study.

30 Mar 2020

The importance of telemedicine during COVID-19 pandemic

A timely paper in Psychotherapy and Psychosomatics illustrates the importance of telemedicine during the COVID-19 pandemic.

30 Mar 2020

Experimental drug could offer new treatment for people with chronic heart failure

An experimental drug recently concluded a successful third-phase clinical trial and could potentially offer a new treatment for about 300,000 Canadians who have worsening chronic heart failure.

30 Mar 2020

Trials find invasive surgery is no better than medication at reducing heart attack risk

Among stable ischemic heart disease patients, invasive procedures do not reduce heart attack or death risk more than medication.

30 Mar 2020

Novel and fully automated technique can speed up detection of stroke

Human emotion system laboratory team at the University of Turku and Turku PET Centre, Finland, introduces a fully automated method for acute ischemic lesion segmentation on brain MRIs and shows how artificial intelligence can reduce the work load of radiologists.

30 Mar 2020

Adding antiplatelet therapy to oral anticoagulants raises risk for TAVR patients with atrial fibrillation

Patients with atrial fibrillation who took oral anticoagulants alone after undergoing transcatheter aortic valve replacement had a lower rate of bleeding complications without an increased risk of clotting-related complications compared to patients who took antiplatelet medication in addition to oral anticoagulants, in a trial presented at the American College of Cardiology's Annual Scientific Session Together with World Congress of Cardiology.

29 Mar 2020

Research characterizes iPS87 cell line as cancer-inducing, stem cell-like cell line

Oncotarget Volume 11, Issue 12 reported outside its natural niche, the cultured prostate cancer stem cells lost their tumor-inducing capability and stem cell marker expression after approximately 8 transfers at a 1:3 split ratio.

27 Mar 2020

Newly developed laboratory model helps reveal how HIV infection affects the brain

Though many negative repercussions of human immunodeficiency virus infection can be mitigated with the use of antiretroviral therapy, one area where medical advances haven't made as much progress is in the reduction of cognitive impacts.

27 Mar 2020

New in vivo priming strategy can be an effective means to enhance cardiac repair

Human stem cells have been regarded as one of the promising cell sources for cardiac regeneration therapy.

27 Mar 2020

New drug shows promise to reverse treatment resistance in advanced multiple myeloma

Researchers at the VU University Medical Center in the Netherlands have tested a new drug in patient samples and mice with multiple myeloma and discovered that it was effective even in advanced disease - a point when many patients currently run out of options.

27 Mar 2020

Research sheds new light on the phage therapy history

In the current situation when the fear of virus infections in the public is common, it is good to remember that some viruses can be extremely beneficial for mankind, even save lives. Such viruses, phages, infect bacteria.

27 Mar 2020

Therapy News and Research

TWILIGHT trial: Brilinta reduces bleeding compared to dual therapy in high-risk coronary patients

Research shows significant difference in radiation response between sexes

'Living drug factories' could be used to achieve long-term treatment of chronic diseases

Monoclonal antibody reduces LDL cholesterol in adult patients with HoFH

Mount Sinai researchers figure out how to ramp up immune system to prevent tumor growth

Houston Methodist receives FDA approval to transfuse donated plasma into a COVID-19 patient

Low-dose rivaroxaban reduces adverse heart events in symptomatic PAD post-intervention

Researchers develop a 'cardiac patch with bioink' to repair the heart

Research could open up new therapeutic strategies for some lung and kidney cancers

Revita DMR therapy has potential to transform lives of patients with poorly controlled type 2 diabetes

The importance of telemedicine during COVID-19 pandemic

Experimental drug could offer new treatment for people with chronic heart failure

Trials find invasive surgery is no better than medication at reducing heart attack risk

Novel and fully automated technique can speed up detection of stroke

Adding antiplatelet therapy to oral anticoagulants raises risk for TAVR patients with atrial fibrillation

Research characterizes iPS87 cell line as cancer-inducing, stem cell-like cell line

Newly developed laboratory model helps reveal how HIV infection affects the brain

New in vivo priming strategy can be an effective means to enhance cardiac repair

New drug shows promise to reverse treatment resistance in advanced multiple myeloma

Research sheds new light on the phage therapy history

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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