B Cell News and Research

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Novel technique developed to observe cancer cells’ metastatic potential

When cancer cells metastasize, they morph, becoming missile-shaped in order to penetrate into other tissues throughout the body.

16 Dec 2021

Gene key to excessive cell proliferation could be a potential target for fatal pulmonary hypertension

A gene that is overexpressed in some aggressive cancers also appears to be key to the excessive cell proliferation that thickens the walls of pulmonary arteries and ultimately causes the right ventricle of the heart to fail, scientists report.

16 Dec 2021

Researchers map how the HTLV-1 virus causes a rare leukemia in some people

An international team have mapped how the HTLV-1 virus causes a rare leukemia in some people, providing clues on how to stop it happening.

16 Dec 2021

Therapeutic antibodies deemed ineffective against Omicron variant of SARS-CoV-2

A new study found that the Omicron S protein evades antibodies with a 44-fold higher efficiency than the Delta variant's spike, rendering therapeutic antibodies ineffective and likely negatively impacting antibody protection induced by infection or double vaccination.

16 Dec 2021

Capability of BNT162b2 vaccine given in 2 or 3 doses to neutralize SARS-CoV-2 Omicron

The team observed that three doses of the BNT162b2 (Pfizer-BioNTech) mRNA vaccine are required to mount an effective antibody response against the Omicron variant.

16 Dec 2021

Experimental and computational synergy considered a promising approach in COVID-19 patients

Thanks to the large amount of -omics data becoming increasingly available, sophisticated computational models are developed for new fields such as immunology and the predictions they generate will help identify key molecules in inflammatory processes.

16 Dec 2021

Scientists find better treatment options for patients with advanced colorectal cancer

City of Hope, a world-renowned cancer research and treatment organization, today announced study results of a Phase 2 clinical trial showing monotherapy with sotorasib resulted in anti-tumor activity and a favorable benefit-risk profile among heavily pretreated patients with advanced colorectal cancer. The research was published today in Lancet Oncology.

16 Dec 2021

T cell responses remain broadly robust against Omicron variant of SARS-CoV-2

A new study highlights the significance of robust T cell responses in preventing severe omicron infections.

16 Dec 2021

Neutralization potency of COVID-19 vaccine boosters against SARS-CoV-2 variant pseudoviruses

A new study has used this assay to evaluate sera, obtained from 239 individuals vaccinated via any of the above-stated vaccines against SARS-CoV-2’s original strain, the Delta, and Omicron SARS-CoV-2 pseudoviruses.

16 Dec 2021

Human monoclonal antibody protects against SARS-CoV-2 and SARS-CoV in vivo

Scientists identified a human monoclonal antibody (mAb), which successfully neutralized or bound all sarbecoviruses tested in vitro.

16 Dec 2021

Researchers identify two new AMD drug candidates using a stem-cell-derived model

Using a stem-cell-derived model, researchers have identified two drug candidates that may slow dry age-related macular degeneration (AMD), a leading cause of blindness for which no treatment exists.

15 Dec 2021

How SARS-CoV-2 affects the male reproductive system

Researchers review the potentially harmful consequences on the male reproductive system in COVID-19 patients.

15 Dec 2021

$1.5 million award helps U-M researchers to gain new window into the inner workings of cells

The precise shapes of proteins at work inside our cells offer essential clues about the processes that drive health and disease. Structural biologists determine the forms of molecular machines, in atomic detail, to better understand how they function or what happens when they malfunction.

15 Dec 2021

B Cell News and Research

Novel technique developed to observe cancer cells’ metastatic potential

Gene key to excessive cell proliferation could be a potential target for fatal pulmonary hypertension

Researchers map how the HTLV-1 virus causes a rare leukemia in some people

Therapeutic antibodies deemed ineffective against Omicron variant of SARS-CoV-2

Capability of BNT162b2 vaccine given in 2 or 3 doses to neutralize SARS-CoV-2 Omicron

Experimental and computational synergy considered a promising approach in COVID-19 patients

Scientists find better treatment options for patients with advanced colorectal cancer

T cell responses remain broadly robust against Omicron variant of SARS-CoV-2

Neutralization potency of COVID-19 vaccine boosters against SARS-CoV-2 variant pseudoviruses

Human monoclonal antibody protects against SARS-CoV-2 and SARS-CoV in vivo

Researchers identify two new AMD drug candidates using a stem-cell-derived model

How SARS-CoV-2 affects the male reproductive system

$1.5 million award helps U-M researchers to gain new window into the inner workings of cells

SARS-CoV-2 VOCs dependent on IFITM2 for efficient infection establishment

First-of-its-kind gene therapy technique reverses severe hearing loss in mice

Weak T-cell clonal response to SARS-CoV-2 vaccination in IBD patients deficient in antibody-responders

WVU researchers explore how a benign virus can be used to treat eye diseases

Combination treatment can effectively inhibit tumor growth

Combination of gallic acid and stretching decreases arthritis inflammation markers in the cells

Researchers take advantage of virus' sweet tooth in the design of sugar-coated COVID-19 test strip

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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