Inflammation News and Research

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Four research teams to study role of exercise in preventing, treating chronic diseases

Canadians will benefit from new insights into the link between physical activity and health as the Honourable Leona Aglukkaq, Minister of Health, today announced funding for four research teams through the Canadian Institutes of Health Research. These teams will study the effects of exercise on the body and its role in the prevention and treatment of chronic diseases including arthritis, breast cancer and heart disease.

27 Jul 2010

NIH awards BU $1.6M grant to target protein-protein interactions with synthetic organic drugs

An interdisciplinary team of Boston University professors is launching a project to develop new ways to target protein-protein interactions with synthetic organic drugs. Financed by a four-year $1.6 million grant from the National Institutes of Health, the goal is to develop new approaches for discovering "drug-like" small molecule inhibitors against challenging protein-protein interaction (PPI) interfaces.

27 Jul 2010

ESC concerned over interpretation of JUPITER sub-analysis trial results about HDL cholesterol

The European Society of Cardiology (ESC) is concerned that interpretations of a paper about cholesterol, published in the Lancet, could act to deter ongoing research efforts into developing new therapeutic strategies to increase high density lipoprotein (HDL) cholesterol. Caution, the ESC experts advise, should be displayed in the interpretation of the results.

26 Jul 2010

Neu5Gc in drugs provokes strong immune response

Researchers at the University of California, San Diego School of Medicine have discovered that a kind of sugar molecule common to chimpanzees, gorillas and other mammals but not found in humans provokes a strong immune response in some people, likely worsening conditions in which chronic inflammation is a major issue.

26 Jul 2010

Inhibiting fatty acid synthase can reduce atherosclerosis: Study

Scientists at Washington University School of Medicine in St. Louis have found a way to significantly reduce atherosclerosis in mice that does not involve lowering cholesterol levels or eliminating other obesity-related problems.

26 Jul 2010

China Sky One Medical receives SFDA approval for producing Ciclopirox Olamine Vaginal Suppositories

China Sky One Medical, Inc., a leading fully integrated pharmaceutical company in the People's Republic of China, today announced that the Company has obtained approval from the State Food and Drug Administration in China for the production of Ciclopirox Olamine Vaginal Suppositories.

23 Jul 2010

New model of inflammatory bowel disease explores interactions of cells in immune system

Scientists at the Virginia Bioinformatics Institute at Virginia Tech have constructed a mathematical and computational model of inflammatory bowel disease that allows researchers to simulate the cellular and molecular changes underlying chronic inflammation in humans. The model allows scientists to explore different interactions of cells in the immune system, check how these cells are linked to inflammation in the colon, and identify intervention points to perhaps stop the disease in its tracks.

23 Jul 2010

Discontinuing epoetin can normalize hemoglobin levels in hemodialysis patients

Discontinuing the anemia drug epoetin may be more effective than reducing the dose for normalizing potentially dangerous high hemoglobin levels in hemodialysis patients, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology. The results provide useful information about the balance required between administering epoetin and achieving target hemoglobin levels.

23 Jul 2010

Researchers block stress responses in cancer surgery patients

Cancer surgery wreaks havoc on a body's immune system and stress hormones exacerbate the problem. As a result, about half of those who undergo surgery for tumor removal experience a recurrence of cancer in the same region or other parts of the body.

22 Jul 2010

Study shows how muscle, fat could play role in survival of heart failure patients

University of Alberta research has discovered heart failure patients with more muscle have the potential to increase their length of life. Antigone Oreopoulos, a researcher from the U of A's School of Public Health, studied 140 patients with heart failure. Study participants underwent a special scan to measure their muscle mass and body fat.

22 Jul 2010

Call for American manufacturers to include medicinal ingredients from around the globe in foods, beverages

As consumers overseas embrace foods and beverages made with ingredients long known to have health and wellness benefits, American manufacturers can take a cue from their success and add such medicinal ingredients to their foods and beverages, according to a scientific discussion at the 2010 Institute of Food Technologists (IFT) Annual Meeting and Food Expo®.

22 Jul 2010

Valproic acid halts vision loss in patients with retinitis pigmentosa

Researchers at the University of Massachusetts Medical School believe they may have found a new treatment for retinitis pigmentosa, a severe neurodegenerative disease of the retina that ultimately results in blindness. One of the more common retinal degenerative diseases, RP is caused by the death of photoreceptor cells and affects 1 in 4,000 people in the United States. RP typically manifests in young adulthood as night blindness or a loss of peripheral vision and in many cases progresses to legal blindness by age 40.

22 Jul 2010

Survey links autism with digestive problems, intestinal inflammation

Autism is the fastest growing developmental disorder in the world. With 1 child in 91 facing the disorder, the diagnosis is more common than pediatric cancer, diabetes, and AIDS combined.

22 Jul 2010

NT-020 nutrients promote adult neural stem cell growth in aged rats: Researchers

A combination of nutrients called NT-020 promoted adult neural stem cell proliferation in aged rats and boosted their memory performance, reported University of South Florida researchers studying natural therapeutic approaches to promoting the health of neurons in the aging brain.

21 Jul 2010

UDCA fails to improve overall histology in NASH patients: Study

A study conducted by researchers at Johann Wolfgang Goethe University in Frankfurt, Germany found that high doses of ursodeoxycholic acid, suggested by some studies to have a beneficial effect on nonalcoholic steatohepatitis, does not improve overall histology in these patients. Full findings of this study are published in the August issue of Hepatology, a journal of the American Association for the Study of Liver Diseases.

21 Jul 2010

UMDNJ identifies direct link between phthalates in plastics and inflammation in newborns

Researchers at the University of Medicine and Dentistry of New Jersey (UMDNJ) have identified a direct link between phthalates, the substances that make plastics more pliable and durable, and inflammation in newborns - and are encouraging more limited use of the plasticizers. Their paper, "Inflammatory Effects of Phthalates in Neonatal Neutrophils," appears in the August 2010 edition of the journal Pediatric Research.

21 Jul 2010

Depressive symptoms in patients with HCV infection overlooked

Researchers from Denmark, Sweden, Norway and Finland (the NORDynamIC project group) have observed that depressive symptoms in patients with hepatitis C virus (HCV) infection are commonly overlooked in routine clinical interviews, and that treatment-induced depression compromises the outcome of HCV therapy. A second U.S. study found that patients with chronic infection had lower (work) productivity and incurred higher medical benefit costs than those without HCV.

21 Jul 2010

La Jolla Institute forms partnership to investigate potential new therapy for sickle cell disease

Researchers from the La Jolla Institute for Allergy & Immunology have joined forces with the Dana-Farber Cancer Institute in Boston and Washington University in St. Louis to investigate a potential new therapy for sickle cell disease, a severe and chronic illness affecting more than 70,000 Americans and several million people worldwide.

21 Jul 2010

Scientists find major shortcomings in assessing CVD risk in HIV patients

At the same time that medical science has nearly eliminated AIDS deaths in patients treated for human immunodeficiency virus, two international meetings of HIV/AIDS scientists and patient advocates find major shortcomings in the design and analysis of studies used to assess cardiovascular disease risk in people with HIV with significant implications for improving medical care.

20 Jul 2010

Gluten free diet reduces inflammation, improves digestion

In 2008, the Garmin-Transitions US Cycling Team experimented with a gluten free diet as a way to improve performance by reducing inflammation, which is important for weeks-long races. The experiment was a success.

17 Jul 2010

Inflammation News and Research

Four research teams to study role of exercise in preventing, treating chronic diseases

NIH awards BU $1.6M grant to target protein-protein interactions with synthetic organic drugs

ESC concerned over interpretation of JUPITER sub-analysis trial results about HDL cholesterol

Neu5Gc in drugs provokes strong immune response

Inhibiting fatty acid synthase can reduce atherosclerosis: Study

China Sky One Medical receives SFDA approval for producing Ciclopirox Olamine Vaginal Suppositories

New model of inflammatory bowel disease explores interactions of cells in immune system

Discontinuing epoetin can normalize hemoglobin levels in hemodialysis patients

Researchers block stress responses in cancer surgery patients

Study shows how muscle, fat could play role in survival of heart failure patients

Call for American manufacturers to include medicinal ingredients from around the globe in foods, beverages

Valproic acid halts vision loss in patients with retinitis pigmentosa

Survey links autism with digestive problems, intestinal inflammation

NT-020 nutrients promote adult neural stem cell growth in aged rats: Researchers

UDCA fails to improve overall histology in NASH patients: Study

UMDNJ identifies direct link between phthalates in plastics and inflammation in newborns

Depressive symptoms in patients with HCV infection overlooked

La Jolla Institute forms partnership to investigate potential new therapy for sickle cell disease

Scientists find major shortcomings in assessing CVD risk in HIV patients

Gluten free diet reduces inflammation, improves digestion

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