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New web-based program helps to determine deadly form of brain cancer

A new web-based program developed by University of Kentucky Markey Cancer Center researchers will provide a simple, free way for healthcare providers to determine which brain tumor cases require testing for a genetic mutation.

20 Aug 2014

Research validates Myc inhibition as effective therapeutic strategy for glioma

Research led by the Vall d'Hebron Institute of Oncology (VHIO) evidence the most conclusive preclinical results to-date validating Myc inhibition as a therapeutic strategy in glioma - a highly agressive tumor type that notoriously outsmarts current anti-cancer therapies.

19 Aug 2014

Viewpoints: Va. GOP's 'Medicaid charade'; Paul Ryan's health Rx for poverty; giving the sick unapproved drugs

Virginia lawmakers will convene in a special session next month to address the question of expanding Medicaid and, more broadly, the fact that hundreds of thousands of poor and disabled people in the state have no health insurance coverage. Democrats and some moderate Republicans have advanced a variety of ideas to tackle that problem. Conservative Republicans, who control the legislature in Richmond, have rejected those solutions while proposing no alternative. Does the GOP intend for the special session to be anything more than a charade at taxpayers' expense? (8/15).

19 Aug 2014

Research findings call for clinical testing of relevant drugs to prevent NASH

Non-alcoholic fatty liver disease (NAFLD) is a common affliction, affecting almost 30 percent of Americans, with a significant number suffering from its most severe form, called non-alcoholic steatohepatitis or NASH, which can lead to cirrhosis and liver cancer. In recent years, NASH has become the leading cause of liver transplantation.

19 Aug 2014

MGH-developed microfluidic device may help study key steps involved in development of tumor metastasis

A microfluidic device developed at Massachusetts General Hospital may help study key steps in the process by which cancer cells break off from a primary tumor to invade other tissues and form metastases.

19 Aug 2014

UC Santa Cruz cancer researcher receives $350,000 to develop novel drugs for breast cancer

UC Santa Cruz cancer researcher Seth Rubin has received a $350,000 grant to fund his work toward the development of a new class of drugs for treating breast cancer. The grant is a Breast Cancer Research Program Breakthrough Award from the congressionally directed medical research programs of the U.S. Department of Defense.

19 Aug 2014

Researchers use microengineered device to show how EMT cancer cells migrate

Using a microengineered device that acts as an obstacle course for cells, researchers have shed new light on a cellular metamorphosis thought to play a role in tumor cell invasion throughout the body.

18 Aug 2014

Microbes influence human eating behavior, dietary choices

It sounds like science fiction, but it seems that bacteria within us — which outnumber our own cells about 100-fold — may very well be affecting both our cravings and moods to get us to eat what they want, and often are driving us toward obesity.

17 Aug 2014

Hippo pathway identifies and prevents progression of abnormal cells into cancer

Researchers from Boston University School of Medicine report that a tumor suppressor pathway, called the Hippo pathway, is responsible for sensing abnormal chromosome numbers in cells and triggering cell cycle arrest, thus preventing progression into cancer.

16 Aug 2014

Enzyme therapy may prevent skeletal abnormalities associated with neurofibromatosis type-1

An enzyme therapy may prevent skeletal abnormalities associated with the genetic disorder neurofibromatosis type-1, Vanderbilt investigators have discovered.

15 Aug 2014

Research offers promise for personalized RNA combination therapies to treat lung cancer

Small RNA molecules, including microRNAs (miRNAs) and small interfering RNAs (siRNAs), offer tremendous potential for new therapeutic agents to inhibit cancer cell growth. However, delivering these small RNAs to solid tumors remains a significant challenge, as the RNAs must target the correct cells and avoid being broken down by enzymes in the body.

15 Aug 2014

Testicular cancer incidence: an interview with Dr Rebecca Johnson, Medical Director, Adolescent and Young Adult Oncology Program Seattle Children's Hospital

We observed that, over the past two decades, there has been an increase in the incidence of testicular cancer in Hispanic American adolescents and young adults (AYAs) between 15 and 39 years of age.

15 Aug 2014

Modified C. novyi-NT bacterium produces precisely targeted anti-tumor response

A modified version of the Clostridium novyi (C. novyi-NT) bacterium can produce a strong and precisely targeted anti-tumor response in rats, dogs and now humans, according to a new report from Johns Hopkins Kimmel Cancer Center researchers.

14 Aug 2014

Caris Life Sciences collaborates with GenoSpace to advance cancer care through research

Caris Life Sciences, a leading biosciences company focused on fulfilling the promise of precision medicine, today announced a collaboration with GenoSpace, a Massachusetts-based technology company that develops robust software solutions for genomic and health data.

14 Aug 2014

Clinical trial tests COXEN model in bladder cancer to find promising treatment

Imagine being able to match a cancer's genes to the best treatment. That's the promise of COXEN (CO eXpression ExtrapolatioN) - a computer program that looks at a panel of cancer genes in a patient's tumor to predict whether it will respond to chemotherapy.

14 Aug 2014

AEG-1 protein blocks effects of retinoic acid in leukemia and liver cancer

Retinoic acid is a form of vitamin A that is used to treat and help prevent the recurrence of a variety of cancers, but for some patients the drug is not effective.

14 Aug 2014

Researchers find priority targets for ovarian cancer immunotherapy

Researchers at Roswell Park Cancer Institute (RPCI) have found that the expression pattern of a unique class of tumor-associated antigens, known as the MAGE cancer-testis antigens (CTAs), correlates with clinical outcome in epithelial ovarian cancer.

14 Aug 2014

Injections of anaerobic bacteria can shrink tumors in rats, dogs and human

Deep within most tumors lie areas that remain untouched by chemotherapy and radiation. These troublesome spots lack the blood and oxygen needed for traditional therapies to work, but provide the perfect target for a new cancer treatment using bacteria that thrive in oxygen-poor conditions.

14 Aug 2014

Recurrence of breast cancer cut by ½ in overweight women who regularly use NSAIDs

Recurrence of hormone-related breast cancer was cut by half in overweight and obese women who regularly used aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs), according to data published in Cancer Research, a journal of the American Association for Cancer Research.

14 Aug 2014

Partial nephrectomy offers near equivalent lengths of cancer control compared to radical nephrectomy

Needle-guided tumor destruction procedures offer near equivalent lengths of local cancer control compared to surgery for patients with small kidney cancer tumors, according to the results of a large study published in the journal European Urology.

13 Aug 2014

Tumor News and Research

New web-based program helps to determine deadly form of brain cancer

Research validates Myc inhibition as effective therapeutic strategy for glioma

Viewpoints: Va. GOP's 'Medicaid charade'; Paul Ryan's health Rx for poverty; giving the sick unapproved drugs

Research findings call for clinical testing of relevant drugs to prevent NASH

MGH-developed microfluidic device may help study key steps involved in development of tumor metastasis

UC Santa Cruz cancer researcher receives $350,000 to develop novel drugs for breast cancer

Researchers use microengineered device to show how EMT cancer cells migrate

Microbes influence human eating behavior, dietary choices

Hippo pathway identifies and prevents progression of abnormal cells into cancer

Enzyme therapy may prevent skeletal abnormalities associated with neurofibromatosis type-1

Research offers promise for personalized RNA combination therapies to treat lung cancer

Testicular cancer incidence: an interview with Dr Rebecca Johnson, Medical Director, Adolescent and Young Adult Oncology Program Seattle Children's Hospital

Modified C. novyi-NT bacterium produces precisely targeted anti-tumor response

Caris Life Sciences collaborates with GenoSpace to advance cancer care through research

Clinical trial tests COXEN model in bladder cancer to find promising treatment

AEG-1 protein blocks effects of retinoic acid in leukemia and liver cancer

Researchers find priority targets for ovarian cancer immunotherapy

Injections of anaerobic bacteria can shrink tumors in rats, dogs and human

Recurrence of breast cancer cut by ½ in overweight women who regularly use NSAIDs

Partial nephrectomy offers near equivalent lengths of cancer control compared to radical nephrectomy

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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