Inflammation News and Research

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Researchers develop world's first T-cell peptide-based vaccine for heart disease

Researchers at Wayne State University have made a fundamental discovery and, in subsequent collaboration with scientists at La Jolla Institute for Allergy and Immunology (LIAI), are one step closer to the goal of developing the world's first T-cell peptide-based vaccine for heart disease - the number one killer in the nation.

17 Jul 2014

Phase III research shows that new drug improves symptoms related to plaque psoriasis

Randomized, phase III research from the University of Alabama at Birmingham shows that a new drug improves symptoms related to moderate to severe plaque psoriasis, a chronic skin disease of scaling and inflammation.

17 Jul 2014

Investigators identify gene that underlies devastating autoinflammatory condition in children

Investigators have identified a gene that underlies a very rare but devastating autoinflammatory condition in children. Several existing drugs have shown therapeutic potential in laboratory studies, and one is currently being studied in children with the disease, which the researchers named STING-associated vasculopathy with onset in infancy (SAVI).

17 Jul 2014

Thirteen scientists receive grant to identify new treatments, cure for psoriasis

Thirteen scientists received a total of $1.05 million in funding from the National Psoriasis Foundation for projects that aim to identify new treatments and a cure for psoriasis—an autoimmune disease that appears on the skin, affecting 7.5 million Americans—and psoriatic arthritis—an inflammatory arthritis that affects the joints and tendons, occurring in up to 30 percent of people with psoriasis.

16 Jul 2014

Chemoprevention and colon cancer: an interview with Dr. John Letterio, Case Western Reserve University School of Medicine

The basic idea of cancer chemoprevention is to arrest or reverse the progression of premalignant cells towards full malignancy, using physiological mechanisms that do not kill healthy cells.

16 Jul 2014

Study: Stress can disrupt process of fat tissue development

Using experimental models, researchers at Boston University School of Medicine (BUSM) showed that adenosine, a metabolite released when the body is under stress or during an inflammatory response, stops the process of adipogenesis, when adipose (fat) stem cells differentiate into adult fat cells.

16 Jul 2014

Mount Sinai awarded AHA grant to prevent heart disease among NYC children and parents

Mount Sinai Heart at Icahn School of Medicine at Mount Sinai has been awarded a $3.8 million grant by the American Heart Association to promote cardiovascular health among high-risk New York City children, and their parents, living in Harlem and the Bronx. With assistance from the NYC Administration for Children's Services, the research team's mission is to reduce each child's future risk of obesity, heart attack, stroke, and type 2 diabetes.

16 Jul 2014

Embolisation of abnormal neovessels relieves osteoarthritic knee pain

Transcatheter arterial embolisation relieves knee pain in patients with moderate osteoarthritis who are resistant to pharmacological pain management, research suggests.

15 Jul 2014

Localised inflammation found in eosinophilic otitis media

Antigen-specific immunoglobulin E is produced locally in the middle ear mucosa of patients with eosinophilic otitis media, clinical research indicates.

15 Jul 2014

Paracetamol safety and osteoarthritis: an interview with Professor David Hunter, University of Sydney

Firstly, paracetamol has been the first-line recommended treatment for osteoarthritis pain for very many years and, secondly, it is readily available over the counter and can be bought in relatively large quantities.

15 Jul 2014

NIH-funded study identifies genetic markers associated with eosinophilic esophagitis

Scientists funded by the National Institutes of Health have identified genetic markers associated with eosinophilic esophagitis (EoE), an inflammatory disease characterized by high levels of immune cells called eosinophils in the esophagus.

15 Jul 2014

Researchers create combination drug that controls both tumor growth and metastasis

Researchers at UC Davis, University of Massachusetts and Harvard Medical School have created a combination drug that controls both tumor growth and metastasis. By combining a COX-2 inhibitor, similar to Celebrex, and an epoxide hydrolase (sEH) inhibitor, the drug controls angiogenesis (blood vessel formation), limiting a tumor's ability to grow and spread.

14 Jul 2014

'Pure mass of HES molecules' explains toxicity to renal tubule cells

The increased risk of kidney injury related to the use of hydroxyethyl starch (HES) in resuscitation fluids reflects the mass of HES molecules, according to a report in Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS).

14 Jul 2014

Computational algorithms provide insight into how gut microbiota respond to infection over time

Being sick due to an infection can make us feel lousy. But what must the ecosystem of bacteria, or microbiota, colonizing our guts be going through when hit with infection? A study from Brigham and Women's Hospital (BWH) has utilized unique computational models to show how infection can affect bacteria that naturally live in our intestines.

14 Jul 2014

BrightFocus offers grants to 55 scientists for Alzheimer's disease and vision research

BrightFocus Foundation, a nonprofit organization funding cutting-edge, innovative research on Alzheimer's disease and the vision diseases of glaucoma and macular degeneration, today announced the recipients of new research grant awards, offered to 55 scientists in 19 U.S. states, the District of Columbia, and five foreign countries.

11 Jul 2014

Bacterial respiratory tract colonization before catching influenza may protect against severe disease

Many studies have shown that more severe illness and even death are likely to result if you develop a secondary respiratory infection after developing influenza. Now, however, a team of researchers based at The Wistar Institute has determined that if you reverse the order of infection, the bacteria Streptococcus pneumoniae (often called pneumococcus) may actually protect against a bad case of the flu.

11 Jul 2014

Baxter International acquires drug candidate developed to treat sickle cell disease

A drug candidate developed by researchers at the NIH's National Center for Advancing Translational Sciences and its collaborators to treat sickle cell disease has been acquired by Baxter International's BioScience business.

11 Jul 2014

Penn receives $8 million grant from NCI to study effects of PDT

Researchers at the Perelman School of Medicine at the University of Pennsylvania in collaboration with the Roswell Park Cancer Institute have received an $8 million grant from the National Cancer Institute (NCI) to study the effects of photodynamic light therapy (PDT) in patients with malignant pleural mesothelioma, a rare, aggressive and deadly cancer that most often manifests itself in the lining of the lungs and is caused almost exclusively by exposure to asbestos.

10 Jul 2014

New class of anti-arthritic drugs reduce arthritic joint inflammation and periodontitis

Inflammatory diseases can occur simultaneously in distinct sites in the same patient, complicating treatment because a medication effective for one disorder may exacerbate the other.

10 Jul 2014

Keck Medicine of USC study identifies potential therapeutic target for inflammation

Molecular microbiologists from the Keck School of Medicine of the University of Southern California have discovered that mice lacking a specific component of the immune system are completely resistant to sepsis, a potentially fatal complication of infection.

10 Jul 2014

Inflammation News and Research

Researchers develop world's first T-cell peptide-based vaccine for heart disease

Phase III research shows that new drug improves symptoms related to plaque psoriasis

Investigators identify gene that underlies devastating autoinflammatory condition in children

Thirteen scientists receive grant to identify new treatments, cure for psoriasis

Chemoprevention and colon cancer: an interview with Dr. John Letterio, Case Western Reserve University School of Medicine

Study: Stress can disrupt process of fat tissue development

Mount Sinai awarded AHA grant to prevent heart disease among NYC children and parents

Embolisation of abnormal neovessels relieves osteoarthritic knee pain

Localised inflammation found in eosinophilic otitis media

Paracetamol safety and osteoarthritis: an interview with Professor David Hunter, University of Sydney

NIH-funded study identifies genetic markers associated with eosinophilic esophagitis

Researchers create combination drug that controls both tumor growth and metastasis

'Pure mass of HES molecules' explains toxicity to renal tubule cells

Computational algorithms provide insight into how gut microbiota respond to infection over time

BrightFocus offers grants to 55 scientists for Alzheimer's disease and vision research

Bacterial respiratory tract colonization before catching influenza may protect against severe disease

Baxter International acquires drug candidate developed to treat sickle cell disease

Penn receives $8 million grant from NCI to study effects of PDT

New class of anti-arthritic drugs reduce arthritic joint inflammation and periodontitis

Keck Medicine of USC study identifies potential therapeutic target for inflammation

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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