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FDA approves new treatment for people with hairy cell leukemia

AstraZeneca and MedImmune, its global biologics research and development arm, announced today that the US Food and Drug Administration has approved LUMOXITI (moxetumomab pasudotox-tdfk) for the treatment of adult patients with relapsed or refractory hairy cell leukemia who have received at least two prior systemic therapies, including treatment with a purine nucleoside analog.

14 Sep 2018

Scientists get unprecedented view of brain development through high-resolution genomic map

Researchers at St. Jude Children's Research Hospital have created a massive database of the changes in gene activity of individual cells in the cerebellum during embryonic development and immediately after birth.

14 Sep 2018

Novel treatment for hairy cell leukemia approved by FDA

The U.S. Food and Drug Administration today approved Lumoxiti (moxetumomab pasudotox-tdfk) injection for intravenous use for the treatment of adult patients with relapsed or refractory hairy cell leukemia (HCL) who have received at least two prior systemic therapies, including treatment with a purine nucleoside analog.

14 Sep 2018

Pear-shaped body is healthier than apple shape

Whether we like it or not, everyone accumulates fat. For women, it usually accumulates around the hips, resulting in a pear-shaped look. In men, fat tends to build up around the abdomen, creating an apple shape.

13 Sep 2018

Drug combination targets pre-leukemia stem cells

Your body's blood cells are manufactured by hematopoietic stem cells in bone marrow. But just as regular, mature cells can become cancerous, so too can stem cells.

12 Sep 2018

Sleep apnea can favor lung cancer growth in young individuals

A scientific study, conducted with animal models, states that sleep apnea can favor lung cancer growth in young individuals. Thus, aging would be a protecting factor against the fast tumor development, induced by this sleep alteration.

12 Sep 2018

Delayed childbearing plays role in increasing number of multiple births

Starting in the 1980s, the number of multiple births -- twins, triplets, quadruplets and quintuplets -- steadily increased from about 20 sets per 1,000 live births to almost 35 sets per 1,000 live births in the 2010s.

12 Sep 2018

Improving early-stage diagnosis of diseases linked to metabolic syndrome

An EU-funded network of universities, hospitals and pharmaceutical and life sciences companies is studying an inflammatory condition associated with a variety of diseases.

12 Sep 2018

Alivio Therapeutics receives DoD grant to advance development of new therapy for IC/BPS

Alivio Therapeutics, an affiliate of PureTech Health plc developing therapies to treat inflammatory disorders through targeted disease immunomodulation, today announced a $3.3 million U.S. Department of Defense Technology/Therapeutic Development Award to advance Alivio's product candidate, ALV-107, for the treatment of interstitial cystitis/bladder pain syndrome with Hunner's lesions.

12 Sep 2018

Study aims to understand role of clopidogrel in patients with cardiovascular disease

Platelet inhibition with aspirin is the cornerstone of medical therapy for coronary artery disease. In the era of percutaneous coronary intervention with drug-eluting stents, dual anti-platelet therapy with the addition of clopidogrel became the mainstay of therapy.

11 Sep 2018

Vomiting - why so common in kids?

Most kids vomit easily and often copiously and frequently. This is a global phenomenon most parents have resigned themselves to. Researchers have now tried to understand why kids vomit so commonly and if there is actually any reason for parents to panic. An article by Erin Blakemore for NPR looks to answer the question.

11 Sep 2018

World Sepsis Day

A series of articles and thought leader interviews for World Sepsis Day on the 10th September 2018, aiming to raise awareness and improve understanding.

10 Sep 2018

Researchers begin trial to reduce risks of major cause of childhood disabilities

Researchers are beginning recruitment in a trial to see if changing pregnant women's hygiene habits could reduce the risks of a major cause of childhood disabilities.

7 Sep 2018

VTCRI scientist receives new federal grant for research into a heart mutation

Steven Poelzing, an associate professor at the Virginia Tech Carilion Research Institute, has received a new five-year grant from the National Heart, Lung, and Blood Institute of the National Institutes of Health.

7 Sep 2018

Probiotics do not really help says latest research

People have been swearing by routine intake of probiotics such as yoghurt and other good bacteria that are supposed to help in prevention of several diseases and maintain good health. A new study from a group of Israeli scientists says that these probiotics are in fact useless. The results of this study appeared in the latest issue of the journal Cell.

7 Sep 2018

Endocrine Society announces winners of prestigious 2019 Laureate Awards

The Endocrine Society today announced it has chosen 13 leading endocrinologists as winners of its prestigious 2019 Laureate Awards, the top honors in the field.

6 Sep 2018

Natural plant compound exploits newly identified Achilles' heel in uveal melanoma

A natural plant compound exploits a newly identified Achilles' heel in a cancer of the eye, uveal melanoma. In human cancer cells growing in the lab, the compound shuts down the overactive signaling that drives uveal melanoma cell growth, according to researchers at Washington University School of Medicine in St. Louis.

6 Sep 2018