B Cell News and Research

RSS

New tool to help map immune escape with SARS-CoV-2 mutations

A new study discusses a computational program that can be used to substitute for actual experimental evidence of the biologic impact of new mutations.

12 Dec 2021

Novel immunotherapy shows promise for children, young adults with recurrent AML

An immunotherapy harnessing the immune system's "natural killer" cells has proven effective in treating acute myeloid leukemia (AML) in some adults whose cancers return.

12 Dec 2021

Infant immune system beats the adult immune system at fighting off new pathogens

As any parent knows, infants are prone to getting respiratory infections.

12 Dec 2021

Newly discovered hormone may play a key role in the development of type 1 and type 2 diabetes

A newly discovered hormone named fabkin helps regulate metabolism and may play an important role in the development of both type 1 and type 2 diabetes, according to research led by the Sabri Ülker Center for Metabolic Research at Harvard T.H. Chan School of Public Health.

12 Dec 2021

Former diabetes drug may help in the treatment of breast cancer, study shows

Findings from a new study led by Yale Cancer Center show the small molecule inhibitor drug, PF05175157, originally developed to treat diabetes by Pfizer, may help in the treatment of breast cancer.

12 Dec 2021

Study provides better understanding of the degenerative underpinnings of Parkinson’s disease

Northwestern investigators have discovered the molecular signature of a subset of dopaminergic neurons with an increased vulnerability to degeneration.

12 Dec 2021

Statistical models predict outcomes for patients receiving non-intensive AML therapy

An international team has developed statistical models to predict the risk of early death in patients being treated with non-intensive therapies for acute myeloid leukemia (AML).

12 Dec 2021

Novel therapy found to be safe and well-tolerated in patients with bone marrow cancer

Mount Sinai physician-scientists have found that a novel therapy for the bone marrow cancer myelofibrosis is safe and well-tolerated and is associated with modest improvements in patients in a Phase 1b clinical trial.

12 Dec 2021

Clinical studies show enhanced responses for lymphoma patients treated with axi-cel CAR T cell therapy

Three clinical studies led by researchers at The University of Texas MD Anderson Cancer Center demonstrated enhanced responses for patients with high-risk lymphoma treated with axicabtagene ciloleucel (axi-cel) chimeric antigen receptor (CAR) T cell therapy.

12 Dec 2021

Researchers discover why people with asthma have lower brain tumor risk

There's not much good that can be said about asthma, a breathing disease in which the airways become narrowed and inflamed.

11 Dec 2021

TP53 mutations in men may predispose to aggressive prostate cancer

Men who have mutations in a gene called TP53 have a high risk of developing aggressive prostate cancer, a multicenter research team in the United States has found.

11 Dec 2021

Nasal vaccine provides broad-based protection against heterologous respiratory viruses in mice

The emergence of COVID-19 variants such as delta and omicron have sent scientists scrambling to determine whether existing vaccinations and boosters are still effective against new strains of SARS-Cov-2.

11 Dec 2021

UCLA research points the way towards a longer-lasting COVID vaccine

Researchers at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have identified rare, naturally occurring T cells that are capable of targeting a protein found in SARS-CoV-2 and a range of other coronaviruses.

11 Dec 2021

Rare population of toxic senescent cells in the brain could be a target for Alzheimer's treatment

For the first time, scientists have identified a rare population of potentially toxic senescent cells in human brains that can serve as a target for a new Alzheimer's disease treatment.

11 Dec 2021

Potentially serious side effect reported after CAR-T cell therapy for multiple myeloma

Mount Sinai scientists have become the first to report a potentially serious side effect related to a new form of immunotherapy known as CAR-T cell therapy, which was recently approved for the treatment of multiple myeloma.

11 Dec 2021

Researchers discover new mechanism behind the formation of membrane vesicles

Canadian and American researchers have discovered a new mechanism by which membrane vesicles are made. These self-contained nanoparticles trap proteins, RNA and other molecules from inside or outside of living cells as nutrients or regulate the numbers of cell surface hormone receptors, such as those for insulin, to control the sensitivity of cells to hormones.

10 Dec 2021

Indication of minor added benefit of nivolumab for adjuvant treatment of esophageal cancer

In an early benefit assessment, the German Institute for Quality and Efficiency in Health Care investigated whether nivolumab has an added benefit over watchful waiting in the adjuvant treatment of adults with carcinoma of the esophagus or the gastroesophageal junction and pathological residual disease after prior neoadjuvant chemoradiotherapy (CRT).

10 Dec 2021

B Cell News and Research

New tool to help map immune escape with SARS-CoV-2 mutations

Novel immunotherapy shows promise for children, young adults with recurrent AML

Infant immune system beats the adult immune system at fighting off new pathogens

Newly discovered hormone may play a key role in the development of type 1 and type 2 diabetes

Former diabetes drug may help in the treatment of breast cancer, study shows

Study provides better understanding of the degenerative underpinnings of Parkinson’s disease

Statistical models predict outcomes for patients receiving non-intensive AML therapy

Novel therapy found to be safe and well-tolerated in patients with bone marrow cancer

Clinical studies show enhanced responses for lymphoma patients treated with axi-cel CAR T cell therapy

Researchers discover why people with asthma have lower brain tumor risk

TP53 mutations in men may predispose to aggressive prostate cancer

Nasal vaccine provides broad-based protection against heterologous respiratory viruses in mice

UCLA research points the way towards a longer-lasting COVID vaccine

Rare population of toxic senescent cells in the brain could be a target for Alzheimer's treatment

Potentially serious side effect reported after CAR-T cell therapy for multiple myeloma

Researchers discover new mechanism behind the formation of membrane vesicles

Indication of minor added benefit of nivolumab for adjuvant treatment of esophageal cancer

Screening FDA-approved compounds shown to possess antiviral or antimicrobial activity for SARS-CoV-2 inhibition

Research suggests targeting fusion peptide-calcium interaction may help treat COVID-19

Study finds sarbecoviruses circulating in wildlife outside Asia can infect human cells

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

Latest News