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PET imaging helps researchers to detect transplant patients with cardiac allograft vasculopathy

Myocardial blood flow and myocardial flow reserve have been identified as accurate indicators for graft failure after cardiac transplantation, according to a new study published in The Journal of Nuclear Medicine.

5 Mar 2020

AI helps reveal apparent cellular distinctions between black and white cancer patients

Scientists at Case Western Reserve University are using Artificial Intelligence (AI) to reveal apparent cellular distinctions between black and white cancer patients, while also exploring potential racial bias in the rapidly developing field of AI.

5 Mar 2020

Innovative method bolsters memory processes in the brain during sleep

A new joint study by Tel Aviv University and Weizmann Institute of Science researchers has yielded an innovative method for bolstering memory processes in the brain during sleep.

5 Mar 2020

Newly developed mobile app helps reduce pain in osteoarthritis patients

By performing a few simple physical exercises daily, and receiving information about their disease regularly, 500 osteoarthritis patients were able to on average halve their pain in 6 months - and improve their physical function.

5 Mar 2020

Researchers create new computer program to map the entire 'hemodynamic landscape' of tumors

Johns Hopkins Medicine researchers have created a computer program for scientists at no charge that lets users readily quantify the structural and functional changes in the blood flow networks feeding tumors.

5 Mar 2020

New type of adoptive cell therapy could target prostate and pancreatic cancers in humans

In experiments with mice, researchers at the Johns Hopkins Kimmel Cancer Center say they have slowed the growth of transplanted human prostate and pancreatic cancer cells by introducing bone marrow cells with a specific gene deletion to induce a novel immune response.

5 Mar 2020

New NGS technique offers quick, accurate diagnosis of sepsis

A report in the Journal of Molecular Diagnostics, published by Elsevier, describes a new technique that uses real-time next-generation sequencing to analyze tiny amounts of microbial cell-free DNA in the plasma of patients with sepsis, offering the possibility of accurate diagnosis of sepsis-causing agents within a few hours of drawing blood.

5 Mar 2020

Study provides new evidence about optimal way to treat BRCA carriers with breast cancer

Commonly known as the breast cancer genes, the BRCA gene family plays a role in repairing damaged DNA. Inherited mutations in the genes BRCA1 or BRCA2 raise the risk of developing breast, ovarian, prostate and other cancers.

5 Mar 2020

Researchers identify mechanism that explains why women experience more pain than men

Imagine taking a pill to control your pain and, instead, the medication actually increases the pain you feel.

5 Mar 2020

New technique helps study peptide-receptor interactions on the cell surface

In the past, biologically-active peptides - small proteins like neurotoxins and hormones that act on cell receptors to alter physiology - were purified from native sources like venoms and then panels of variants were produced in bacteria, or synthesized, to study the structural basis for receptor interaction.

5 Mar 2020

Combined biopsy more likely to detect aggressive prostate cancers than standard biopsy alone

Using a combination of magnetic resonance imaging (MRI) to target and sample suspicious prostate tissue along with a standard prostate biopsy is significantly more likely to detect the most aggressive prostate cancers than standard biopsy alone.

5 Mar 2020

Respiratory antivirals and risk to breastfeeding women

Little data is available about the ability of antiviral drugs used to treat COVID-19, coronavirus, to enter breastmilk, let alone the potential adverse effects on breastfeeding infants.

4 Mar 2020

Nearly $4 million to fund drug discovery research for Alzheimer's, other dementia

The Alzheimer's Association and the Rainwater Charitable Foundation have joined forces again to fund drug discovery research towards finding therapies for Alzheimer's disease, frontotemporal degeneration, and other tauopathies.

4 Mar 2020

Study shows protective effect of bilingualism against dementia

The conclusions of a study carried out by Víctor Costumero, as the first author, Marco Calabria and Albert Costa (died in 2018), members of the Speech Production and Bilingualism group at the Cognition and Brain Center (CBC) of the Department of Information Technology and the Communications of the UPF, together with researchers from the Universities of Jaume I, Valencia, Barcelona and Jaén; IDIBELL, Hospital La Fe (Valencia) and Grupo Médico ERESA (Valencia) show that bilingualism acts as a cognitive reserve factor against dementia.

4 Mar 2020

Mayo research provides evidence supporting benefit of ablation for heart failure patients with AFib

Only 1 in 13 everyday patients could have participated in a pivotal international clinical trial looking at the use of catheter ablation to treat atrial fibrillation among people with heart failure.

4 Mar 2020

Antidepressant shows promise in helping men with recurrent prostate cancer

An antidepressant in use for decades, repurposed to fight prostate cancer, shows promise in helping patients whose disease has returned following surgery or radiation, a pilot study at USC shows.

4 Mar 2020

Preclinical data of Ocugen's OCU400 genetic modifier published in Nature Gene Therapy

Ocugen, Inc., a clinical-stage company focused on discovering, developing and commercializing transformative therapies to treat rare and underserved ophthalmic diseases, announced today the publication in Nature Gene Therapy of preclinical data of nuclear hormone receptor gene NR2E3 as a genetic modifier and therapeutic agent to treat multiple retinal degenerative diseases.

3 Mar 2020

Therapy News and Research

PET imaging helps researchers to detect transplant patients with cardiac allograft vasculopathy

AI helps reveal apparent cellular distinctions between black and white cancer patients

Innovative method bolsters memory processes in the brain during sleep

Newly developed mobile app helps reduce pain in osteoarthritis patients

Researchers create new computer program to map the entire 'hemodynamic landscape' of tumors

New type of adoptive cell therapy could target prostate and pancreatic cancers in humans

New NGS technique offers quick, accurate diagnosis of sepsis

Study provides new evidence about optimal way to treat BRCA carriers with breast cancer

Researchers identify mechanism that explains why women experience more pain than men

New technique helps study peptide-receptor interactions on the cell surface

Combined biopsy more likely to detect aggressive prostate cancers than standard biopsy alone

Respiratory antivirals and risk to breastfeeding women

Nearly $4 million to fund drug discovery research for Alzheimer's, other dementia

Study shows protective effect of bilingualism against dementia

Mayo research provides evidence supporting benefit of ablation for heart failure patients with AFib

Antidepressant shows promise in helping men with recurrent prostate cancer

Preclinical data of Ocugen's OCU400 genetic modifier published in Nature Gene Therapy

Evaluating the safety and effectiveness of investigational drug to manage pediatric myopia

Inhibiting energy production in immune T-cells allows some tumors to escape treatment

Inhibiting specific protein could make radiation therapy for colon cancer more effective

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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