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SARS-CoV-2 virus-like particles elicit potent neutralizing antibody response in variant challenge

Researchers develop a virus-like particle for SARS-CoV-2 based on the co-expression of the spike, membrane, and envelope structural proteins.

6 Dec 2021

Using soft X-ray tomography for 3D imaging of cell structures in few minutes

Viral pathogens like the SARS-CoV-2 coronavirus change the interior structure of the cells they infect. These changes occur at the level of individual cell components – the organelles – and can provide information on how viral diseases develop.

6 Dec 2021

Researchers use gene-editing to create single sex mice litters

Scientists at the Francis Crick Institute, in collaboration with University of Kent, have used gene editing technology to create female-only and male-only mice litters with 100% efficiency.

6 Dec 2021

New protein variant underlies the ability of gastric cancers to resist chemotherapy

A new protein variant underlies the ability of gastric cancers to resist an otherwise effective family of chemotherapy drugs, according to a study by a multidisciplinary team at Weill Cornell Medicine. The results suggest a treatment strategy that could improve the prognoses of many patients with cancer.

6 Dec 2021

Colorimetric detection of SARS-CoV-2 viral RNA by an in vitro transcription/translation assay

This work has emphasized the clinical and translational potential of paper-based biosensors.

6 Dec 2021

SARS-CoV-2 immune memory in mRNA vaccine recipients

Researchers measured SARS-CoV-2–specific antibody, memory B cell, and memory T cell responses in a group of healthy subjects who generated primary immune responses to two doses of mRNA vaccine compared to a group of SARS-CoV-2–recovered vaccines.

6 Dec 2021

Announcing the Winners of The Scientist’s Top 10 Innovations of 2021

Each year The Scientist seeks to highlight the latest and greatest tools, technologies, and techniques to hit the life science landscape.

From Resolve Biosciences 6 Dec 2021

The link between cytokine storms and cardiovascular problems in COVID-19 patients

New findings may help doctors choose effective COVID-19 treatment regimens for patients with heart complications.

6 Dec 2021

Sino Biological Launches A Panel of Research Reagents for SARS-CoV-2 Omicron Variant (B.1.1.529)

Sino Biological, Inc. (https://www.sinobiological.com; SHE: 301047) announced today that it has launched a panel of research reagents for the newly identified Omicron variant (B.1.1.529) of the SARS-CoV-2 virus

From Sino Biological Inc. 6 Dec 2021

Mutations in a crucial gene responsible for chemotherapy failure in some blood cancer patients

Mutations in a crucial gene are the key reason that chemotherapy fails in some patients with blood cancer, a study by Nanyang Technological University, Singapore (NTU Singapore) and Singapore General Hospital (SGH) has found.

6 Dec 2021

Daytime meals can help regulate bloodstream glucose levels in night shift workers

What are the effects of eating during the nighttime instead of the daytime? New research, focused on a simulation of night shift work, may hold implications for people eating at atypical times - like those experiencing jet lag, circadian rhythm sleep disorders, or who tend to sleep late during the weekends.

6 Dec 2021

A new model linking SARS-CoV-2 viral load to infectiousness may guide further testing strategy

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5 Dec 2021

SARS-CoV-2 ORF10 degrades mitochondrial antiviral signaling protein to suppress immune response

A novel mechanism by which SARS-CoV-2 inhibits the innate immune response; that is, ORF10 induces mitophagy-mediated MAVS degradation by binding to NIX.

5 Dec 2021

Preclinical data shows enhanced T-cell responses & neutralization of SARS-CoV-2 variants with ImmunityBio heterologous vaccination

A new study supports the hypothesis that heterologous vaccination can provide an increased immune response against virus infection, supporting several other studies that have indicated similar events.

5 Dec 2021

New approach to COVID-19 immune profiling using blood-based machine learning

A new study discusses the application of a novel deconvolution model AImmune to predict moderate and severe cases of COVID-19.

5 Dec 2021

Research offers a phylogenetic and ontogenetic overview of the primitive streak

In their publication in Science, Professor Guojun Sheng (Kumamoto University, Japan), Professor Alfonso Martinez Arias (Universidad Pompeu Fabra, Spain) and Professor Ann Sutherland (University of Virginia Health System, USA) offer a phylogenetic and ontogenetic overview of the primitive streak and its role in mediating amniote (vertebrate animals that develop on land) gastrulation, and discuss the implications of embryonic stem cell-based models of early mammalian embryogenesis on the function of this structure.

4 Dec 2021

Systematic review: The involvement of bitter taste receptors in cancer

Humans have 25 different types of functional bitter taste receptors. These are found on our tongue, where they facilitate the taste perception of bitter tasting compounds. In addition, there are increasing findings that cells of extra-oral organs also have such receptors.

4 Dec 2021

B Cell News and Research

SARS-CoV-2 virus-like particles elicit potent neutralizing antibody response in variant challenge

Using soft X-ray tomography for 3D imaging of cell structures in few minutes

Researchers use gene-editing to create single sex mice litters

New protein variant underlies the ability of gastric cancers to resist chemotherapy

Colorimetric detection of SARS-CoV-2 viral RNA by an in vitro transcription/translation assay

SARS-CoV-2 immune memory in mRNA vaccine recipients

Announcing the Winners of The Scientist’s Top 10 Innovations of 2021

The link between cytokine storms and cardiovascular problems in COVID-19 patients

Sino Biological Launches A Panel of Research Reagents for SARS-CoV-2 Omicron Variant (B.1.1.529)

Mutations in a crucial gene responsible for chemotherapy failure in some blood cancer patients

Daytime meals can help regulate bloodstream glucose levels in night shift workers

A new model linking SARS-CoV-2 viral load to infectiousness may guide further testing strategy

SARS-CoV-2 ORF10 degrades mitochondrial antiviral signaling protein to suppress immune response

Preclinical data shows enhanced T-cell responses & neutralization of SARS-CoV-2 variants with ImmunityBio heterologous vaccination

New approach to COVID-19 immune profiling using blood-based machine learning

Research offers a phylogenetic and ontogenetic overview of the primitive streak

Systematic review: The involvement of bitter taste receptors in cancer

Researchers develop new approach to print skin equivalents

Cancer registry offers a better understanding of ovarian granulosa cell tumors

'Combination' adjuvant may boost the protective power of vaccines

Using single B cell screening to boost antibody discovery eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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