Genetic News and Research

RSS

Yale-led study provides roadmap to discover new treatment for idiopathic pulmonary fibrosis

A Yale-led collaborative study boosts scientific understanding of how the lung disease idiopathic pulmonary fibrosis (IPF) progresses, providing a roadmap for researchers to discover new treatment targets for the disease.

15 Nov 2019

Study: 15,000 cases of hypophosphatasia potentially undetected in Spanish population

Hypophosphatasia (HPP) is a rare and serious hereditary disease that is potentially life-threatening and is caused by one or more mutations in the gene coding for alkaline phosphatase (ALPL). It is frequently misdiagnosed.

15 Nov 2019

UCI researchers develop new cell therapy to improve memory, prevent seizures after TBI

Researchers from the University of California, Irvine developed a breakthrough cell therapy to improve memory and prevent seizures in mice following traumatic brain injury.

15 Nov 2019

Mining 'darkest' parts of the genome in cancer cells yields gold

Mining the rich uncharted territory of the genome or genetic material of a cancer cell has yielded gold for Princess Margaret scientists: new protein targets for drug development against prostate cancer.

15 Nov 2019

Broccoli's effects on kidney health may depend on individual's genetics

New research indicates that the benefits of a dietary compound on kidney health may depend on an individual's genetics. The findings, which appear in an upcoming issue of JASN, may be helpful for tailoring interventions to prevent or treat kidney disease.

15 Nov 2019

Key Alzheimer's gene variants act differently among Caribbean Hispanics based on ancestry

Researchers looking to uncover the mysteries of Alzheimer's disease have revealed new insights from old variants.

15 Nov 2019

Scientists reverse learning and memory deficits with drugs in animal model of Down syndrome

In a surprising finding using the standard animal model of Down syndrome (DS), scientists were able to correct the learning and memory deficits associated with the condition -- the leading genetic cause of cognitive disability and the most frequently diagnosed chromosomal disorder in the U.S. -- with drugs that target the body's response to cellular stresses.

15 Nov 2019

Study unravels how insulin interacts with its receptor

Since the discovery of insulin nearly 100 years ago, scientists have explored how it interacts with its receptor with the goal of improving the ability of therapeutic insulins to mimic the way insulin works in the body.

14 Nov 2019

Non-coding enhancer DNA may be key for identifying genetic risk in neurological conditions

One might think that the primary cause of most genetically linked diseases comes from mutations in coding DNA -- alterations in coding regions of the genome that can lead directly to changes in the expression of particular proteins important for a healthy body.

14 Nov 2019

Altering malarial parasite genes to prevent malaria

Malaria is a mosquito-borne disease caused by the parasitic organism called Plasmodium, of which there are several types that cause the different kinds of malarial fever. This age-old infection still kills over 400,000 people every year, all over the world. A new study published in the journal Cell on November 14, 2019, shows how a simple tweaking of the genes of this organism could quite conceivably lead to the elimination of this disease altogether.

14 Nov 2019

Study sheds light on how Zika virus causes microcephaly in newborns

A new study led by researchers at Baylor College of Medicine revealed how in utero Zika virus infection can lead to microcephaly in newborns. The team discovered that the Zika virus protein NS4A disrupts brain growth by hijacking a pathway that regulates the generation of new neurons.

14 Nov 2019

TACC announces role as key collaborator in NIH grant to study chronic pain and opioid dependence

Pain impacts nearly every individual at some point in their lives. With more than 25 million adults in the U.S. experiencing daily pain, the U.S. is facing a crisis due to the high prevalence of chronic pain and associated opioid use disorder and overdose deaths.

14 Nov 2019

New insights into how immune system and inflammation play a role in PD

Relatively new research findings indicating that the earliest stages of Parkinson's disease (PD) may occur in the gut have been gaining traction in recent years. In a review published in the Journal of Parkinson's Disease, Tomasz Brudek, PhD, evaluates evidence for the association between inflammatory bowel disease (IBD) and PD and proposes directions for future research.

14 Nov 2019

Study supports positive associations with mother-child bonding experiences during and after pregnancy

A study in the Journal of the American Academy of Child and Adolescent Psychiatry, published by Elsevier, reports that home-visiting by trained community workers during and after pregnancy can improve mother-child interactions in the first years of life.

14 Nov 2019

Promising method to identify aggressive breast cancers that will respond to immunotherapy

University of North Carolina Lineberger Comprehensive Cancer Center researchers have discovered a promising method to identify aggressive breast cancer tumors that will respond to drugs that unleash the immune system against cancer.

14 Nov 2019

FDA grants acceptance to application for selumetinib as treatment for neurofibromatosis

AstraZeneca and MSD (Merck) announced today that the U.S. Food and Drug Administration (FDA) has granted acceptance to file status of its application for the MEK inhibitor selumetinib, for use in patients with plexiform neurofibromas, a common manifestation in the disease neurofibromatosis type one (NF1).

14 Nov 2019

New computational model could help in the development of anti-cancer drugs

Researchers from the Faculty of Medicine and the Institute for Molecular Medicine at the University of Helsinki have developed a computational model, Combined Essentiality Scoring (CES) that enables accurate identification of essential genes in cancer cells for development of anti-cancer drugs.

14 Nov 2019

Researchers develop, test new blood assay that predicts patients at risk of death from sepsis

After decades of little or no progress, biomedical researchers are finally making some headway at detecting and treating sepsis, a deadly medical complication that sends a surge of pathogenic infection through the body and remains a major public health problem.

14 Nov 2019

Simple 'nudges' help improve heart patients' adherence to statins

Statins are an effective medication for treating patients with heart disease - they cut the risk of a second major adverse cardiac event by almost 50 percent. But only about six percent of patients take statins as prescribed. One way to solve that? Nudge them. Literally.

14 Nov 2019

Fight for Sight funds new project to create UK’s first large-scale glaucoma biobank

Fight for Sight is funding a project to create the UK’s first large-scale glaucoma biobank, a new tool that will help personalize glaucoma treatment and identify patients most at risk of sight loss.

14 Nov 2019

Genetic News and Research

Yale-led study provides roadmap to discover new treatment for idiopathic pulmonary fibrosis

Study: 15,000 cases of hypophosphatasia potentially undetected in Spanish population

UCI researchers develop new cell therapy to improve memory, prevent seizures after TBI

Mining 'darkest' parts of the genome in cancer cells yields gold

Broccoli's effects on kidney health may depend on individual's genetics

Key Alzheimer's gene variants act differently among Caribbean Hispanics based on ancestry

Scientists reverse learning and memory deficits with drugs in animal model of Down syndrome

Study unravels how insulin interacts with its receptor

Non-coding enhancer DNA may be key for identifying genetic risk in neurological conditions

Altering malarial parasite genes to prevent malaria

Study sheds light on how Zika virus causes microcephaly in newborns

TACC announces role as key collaborator in NIH grant to study chronic pain and opioid dependence

New insights into how immune system and inflammation play a role in PD

Study supports positive associations with mother-child bonding experiences during and after pregnancy

Promising method to identify aggressive breast cancers that will respond to immunotherapy

FDA grants acceptance to application for selumetinib as treatment for neurofibromatosis

New computational model could help in the development of anti-cancer drugs

Researchers develop, test new blood assay that predicts patients at risk of death from sepsis

Simple 'nudges' help improve heart patients' adherence to statins

Fight for Sight funds new project to create UK’s first large-scale glaucoma biobank

Genetics & Genomics - Second Edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Latest News