Menopause News and Research

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Menopause is the time in a woman's life when her period stops. It usually occurs naturally, most often after age 45. Menopause happens because the woman's ovary stops producing the hormones estrogen and progesterone.

FSH-specific polyclonal antibody might offer more effective way to prevent osteoporosis

A new study suggests that a polyclonal antibody that blocks follicle-stimulating hormone (FSH) in mice without ovaries might offer a more effective way to prevent or arrest osteoporosis than currently available treatments.

21 Aug 2012

PD risk factors for potential clinical screening identified

A meta-analysis has identified 19 risk factors that significantly impact a person’s risk for Parkinson’s disease and could be of potential value for clinical screening, say the authors.

20 Aug 2012

Calcium and vitamin D supplements do not prevent bone loss in men with prostate cancer

Prescribing calcium and vitamin D supplements for men at risk of bone loss from hormonal treatment for prostate cancer seems like good medicine.

8 Aug 2012

Alcohol decreases turnover of bone in post-menopausal women

Women after menopause tend to develop weaker bones from what is known as osteoporosis, which may lead to fractures (especially hip fractures) from falling. The weakness of the bones results from an imbalance between the normal resorption (a type of dissolving of old bone) and the laying down of new bone, an ongoing process for both men and women referred to as "bone turnover."

3 Aug 2012

Depomed submits Serada NDA with FDA for treatment of menopausal hot flashes

Depomed, Inc. today announced that it has submitted a New Drug Application (NDA) for Serada to the United States Food and Drug Administration. Serada is Depomed's proprietary extended release formulation of gabapentin in development for the treatment of menopausal hot flashes.

31 Jul 2012

Aging women show nonlinear declines in fitness, activity levels

Physical activity levels and cardiorespiratory fitness in women do not decline in a linear manner with age, research shows.

23 Jul 2012

Novartis receives FDA approval for Afinitor to treat HER2-negative breast cancer

The U.S. Food and Drug Administration today approved Afinitor (everolimus) for use in combination with Aromasin (exemestane) to treat certain postmenopausal women with advanced hormone-receptor positive, HER2-negative breast cancer.

21 Jul 2012

EMA accepts Pfizer’s bazedoxifene/conjugated estrogens MAA for review

Pfizer Inc. today announced that the European Medicines Agency (EMA) accepted for review the Marketing Authorization Application (MAA) for bazedoxifene/conjugated estrogens (BZA/CE), a potential new medicine for postmenopausal women with a uterus for the treatment of estrogen deficiency symptoms and treatment of osteoporosis in women at risk of fracture.

19 Jul 2012

More reason to restrict hormone therapy during menopause

Researchers have found further evidence to show that menopausal hormone therapy increases the risk for high blood pressure in postmenopausal women.

13 Jul 2012

Low-fat, high fruit and vegetable diet may help reduce menopausal symptoms

Weight loss that occurs in conjunction with a low-fat, high fruit and vegetable diet may help to reduce or eliminate hot flashes and night sweats associated with menopause, according to a Kaiser Permanente Division of Research study that appears in the current issue of Menopause.

12 Jul 2012

Moderate alcohol intake may reduce risk of osteoporosis in postmenopausal women

Drinking a moderate amount of alcohol as part of a healthy lifestyle may benefit women's bone health, lowering their risk of developing osteoporosis.

12 Jul 2012

Relaxin key to improved stroke rehabilitation outcomes

Treatment with the reproductive hormone relaxin during physical rehabilitative therapy appears to improve long-term outcomes in stroke patients over rehabilitative therapy alone, say researchers.

10 Jul 2012

Combination of estrogen and MPA increases synapses in the prefrontal cortex

A new study of aged female rats found that long-term treatment with estrogen and a synthetic progesterone known as MPA increased levels of a protein marker of synapses in the prefrontal cortex, a brain region known to suffer significant losses in aging.

10 Jul 2012

Hormone therapy still an acceptable treatment for menopausal symptoms: New joint statement

After 10 years of debate regarding the risks and benefits of hormone therapy, 15 top medical organizations have come together to issue a statement of agreement regarding the benefits of hormone therapy for symptomatic menopausal women. It was July 9, 2002, when the controversial, highly publicized Women's Health Initiative (WHI) published its assessment of hormone therapy for the prevention of chronic disease and concluded that risks exceeded benefits.

10 Jul 2012

Miriam Hospital receives NIH renewal grant to support growth of Lifespan/Tufts/Brown CFAR

The Miriam Hospital has received an $8.5 million, five-year renewal grant from the National Institutes of Health (NIH) to support the continued growth of the Lifespan/Tufts/Brown Center for AIDS Research (CFAR).

28 Jun 2012

Menopausal women may experience fewer hot flashes following physical activity

Menopausal women who exercise may experience fewer hot flashes in the 24 hours following physical activity, according to health researchers.

28 Jun 2012

Positive results from Antares Pharma's VIBEX MTX human factors usability study for RA

Antares Pharma, Inc. today announced positive results from a human factors usability study for VIBEX Methotrexate (MTX), a proprietary auto injector product designed to self-administer a rapid subcutaneous weekly injection of methotrexate for the treatment of rheumatoid arthritis (RA).

26 Jun 2012

Common experience of menopausal symptoms not associated with heart disease risk

The hot flashes and night sweats that most women experience early in menopause are not linked to increased levels of cardiovascular disease risk markers unless the symptoms persist or start many years after menopause begins. These new study results will be presented Saturday at The Endocrine Society's 94th Annual Meeting in Houston.

25 Jun 2012

Physical activity linked with reduced risk of breast cancer

A new analysis done by University of North Carolina at Chapel Hill researchers has found that physical activity - either mild or intense and before or after menopause - may reduce breast cancer risk, but substantial weight gain may negate these benefits.

25 Jun 2012

Researchers discover distinct differences in how muscle affects two layers of bone in men, women

Researchers have long been aware that the progressive loss of muscle mass and bone density is a natural part of aging. But little work has investigated how muscle tissue affects the inner and outer layers of bone microstructure.

21 Jun 2012