Metastasis News and Research

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Metastasis is the spread of cancer from one part of the body to another. A tumor formed by cells that have spread is called a “metastatic tumor” or a “metastasis.” The metastatic tumor contains cells that are like those in the original (primary) tumor. The plural form of metastasis is metastases

Researchers understand cues controlling collective cell migration during development

Collective cell migration, where groups of cells move together with a common purpose, is important for processes ranging from wound healing to tumor metastasis.

6 Feb 2019

Rare stem cell may be the root of all metastatic cancers

Researchers have discovered a rogue stem cell that could be the cause of all metastatic cancers. The breakthrough could affect all future research projects.

6 Feb 2019

Researchers find 'origin' of cancer spread

The discovery of the cell, which they are calling 'the cell of origin' sheds new light on what fuels cancer growth and how to potentially stop it.

4 Feb 2019

Cancer nanomedicine may accelerate metastasis, NUS study finds

Nanoparticles can be found in processed food (e.g. food additives), consumer products (e.g. sunscreen) and even in medicine. While these tiny particles could have large untapped potential and novel new applications, they may have unintended and harmful side effects, according to a recent study by researchers from the National University of Singapore.

1 Feb 2019

Japanese researchers develop highly sensitive method to detect potential cancer biomarker

Exosomes regulate intercellular communication in cancers, and are drawing attention as a potential cancer biomarker. A Japanese research group has developed a highly sensitive method for detecting these exosomes that could potentially contribute to early detection of cancer.

31 Jan 2019

Nine early career scientists named 2019 recipients of the Damon Runyon-Rachleff Innovation Award

The Damon Runyon Cancer Research Foundation announced that nine scientists with novel approaches to fighting cancer have been named 2019 recipients of the Damon Runyon-Rachleff Innovation Award.

24 Jan 2019

Scientists propose quick and pain-free method for diagnosing kidney cancer

Sechenov University together with their German colleagues suggest a new highly sensitive, quick, and pain-free method for diagnosing kidney cancer.

21 Jan 2019

UNIST researcher named as recipient of Merck’s 2018 Life Science Awards

Jun Ho Lee, a doctroral student in Life Sciences at UNIST, has been named as a recipient of Merck's 2018 Life Science Awards in Tumor Biology, receiving the grand prize of $10,000.

21 Jan 2019

New nuclear medicine method could improve detection of primary and metastatic melanoma

A new nuclear medicine method for detecting malignant melanoma, one of the most aggressive skin cancers, has been successfully tested for the first time in humans and could improve detection of both primary and metastatic melanoma.

18 Jan 2019

New anti-inflammatory compound acts as 'surge protector' to reduce cancer growth

A new anti-inflammatory compound developed at the University of California, Davis, acts as a "surge protector" to suppress inflammation and reduce cancer growth, at least in mouse models of cancer.

17 Jan 2019

Breast cancers more likely to metastasize in young women within 10 years of giving birth

A study by researchers at University of Colorado Cancer Center and Oregon Health & Science University published today in the Journal of the American Medical Association Network shows that breast cancers diagnosed in young women within 10 years of giving birth are more likely to metastasize, and thus more likely to cause death, than breast cancers in young women who gave birth less recently or not at all.

17 Jan 2019

Research reveals novel approach to suppressing chemotherapy-induced tumor growth

Following up on a groundbreaking 2018 study in which BIDMC's Dipak Panigrahy, MD, demonstrated that dead and dying cancer cells killed by conventional cancer treatments paradoxically trigger inflammation that promotes tumor growth and metastasis, a new study led by Allison Gartung, PhD, describes a novel approach to suppressing chemotherapy-induced tumor growth in an ovarian cancer model.

16 Jan 2019

FDA-approved drug hampers cancer metastasis in animal model, shows study

For cancer to spread, it needs a hospitable environment in distant organs. This fertile "soil" can provide a home to circulating malignant cells.

16 Jan 2019

Molecular hallmarks of tumor hypoxia across 19 cancer types discovered

Unlike healthy tissues, tumors thrive in low-oxygen environments, often acquiring the ability to resist treatment and spread to other sites in the body. Despite being a well-known cause of therapy resistance and metastasis, the impact of low oxygen, known as hypoxia, on tumor cells is poorly understood.

14 Jan 2019

Turning breast cancer cells into fat cells prevents the formation of metastases

An innovative combination therapy can force malignant breast cancer cells to turn into fat cells. This can be used to prevent the formation of metastases in mice, as researchers at the University of Basel's Department of Biomedicine recently reported in the journal Cancer Cell.

14 Jan 2019

New research could have a significant impact on cancer therapy

Research led by Suresh Alahari, PhD, the Fred Brazda Professor of Biochemistry and Molecular Biology at LSU Health New Orleans School of Medicine, has found a new role for a protein discovered by his lab in preventing the growth and spread of breast cancer.

11 Jan 2019

A small protein plays key role in how cancer stem cells differentiate

A jagged little protein appears to be key to how cancer stem cells differentiate and enable metastasis, according to researchers at Rice University and the Duke University School of Medicine.

4 Jan 2019

Study uncovers how tumors backfire on neoadjuvant chemotherapy

Some patients with breast cancer receive chemotherapy before the tumor is removed with surgery. This approach, called 'neoadjuvant' therapy, helps to reduce the size of the tumor to facilitate breast-conserving surgery, and can even eradicate the tumor, leaving few or no cancerous cells for the surgeon to remove.

2 Jan 2019

Researchers conduct psycho-educational study on early stage breast cancer patients

Cancer is a psychologically traumatic experience for affected individuals. Chemotherpautic medications can also be painful to the same patients.

28 Dec 2018

CWRU researcher receives nearly $1 million to study drug resistance mechanisms in prostate cancer

Sanjay Gupta, PhD, of Case Western Reserve University School of Medicine and University Hospitals Cleveland Medical Center will receive $962,000 over three years to investigate drug resistance mechanisms in prostate cancer.

24 Dec 2018