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Studying yeast could unlock new ways to make cancer cells more vulnerable

What can stressed yeast teach us about fundamental processes in the cell? A lot, according to scientists at the European Molecular Biology Laboratory (EMBL). The team studies, among other topics, how cells adapt to stress -- such as nutrient deprivation.

9 Oct 2024

Novel compounds show promise in fighting COVID-19

New research from The Wistar Institute's Salvino lab - led by professor Joseph Salvino, Ph.D. - has identified a novel series of SARS-CoV-2 Mpro inhibitors that may lead to potential new COVID-19 treatments that, according to preclinical testing, effectively inhibits COVID-19 and synergizes with existing anti-COVID therapies.

8 Oct 2024

Policy change linked to rise in treatment-resistant vaginal thrush

A change in policy may be helping to drive a rise in treatment-resistant vaginal thrush, amid significant yearly increases in the prevalence of fungal infections caused by fungal Candida species, suggests the first study of its kind, published online in the journal Sexually Transmitted Infections.

8 Oct 2024

Breakthrough study reveals Entropic Pulling mechanism of Hsp70 chaperones

Proteins control most of the body's functions, and their malfunction can have severe consequences, such as neurodegenerative diseases or cancer.

8 Oct 2024

Study identifies RNA molecule crucial for skin wound healing

A new study from Karolinska Institutet in Sweden and the Chinese Academy of Medical Sciences has identified an RNA molecule that is important for skin wound healing.

8 Oct 2024

New insights into how stress affects pancreatic cells and diabetes risk

The cells in your pancreas, like people, can only handle so much stress before they start to break down. Certain stressors, such as inflammation and high blood sugar, contribute to the development of type 2 diabetes by overwhelming these cells.

8 Oct 2024

Heat stress impacts development of babies during critical early years

Exposure to high levels of heat may both impact the growth of fetuses during pregnancy and infants up to the age of two, a new analysis suggests.

8 Oct 2024

Global analysis reveals disparities in access to new cancer drugs

Despite considerable progress in the discovery and development of new cancer drugs, there are significant disparities in both the availability and timeliness of these medicines worldwide, with poorer countries missing out, suggests a global analysis of new drug launches between 1990 and 2022, published in the open access journal BMJ Global Health.

8 Oct 2024

$Longer waits in emergency care impact outcomes for hip fracture patients, study shows$

Longer waits in emergency care impact outcomes for hip fracture patients, study shows

Waiting more than 4 hours in emergency care for treatment is linked to heightened risks of death and a longer hospital stay for hip fracture patients, reveals a single centre study, published online in Emergency Medicine Journal.

8 Oct 2024

Increasing cases of mosquito-borne diseases call for greater awareness

The hospitalization last summer of Dr. Anthony Fauci, former head of the National Institute of Allergy and Infectious Diseases, with West Nile virus – and his account of it this week in the New York Times – have helped raise public awareness of the dangers of mosquito borne-illness, which can range from Zika and malaria to dengue and West Nile virus.

8 Oct 2024

Understanding proteasome function in Trichomonas vaginalis for drug development

Researchers from IOCB Prague are furthering the understanding of how medicines work and what it takes to develop their most effective variants.

8 Oct 2024

Study highlights rising rates of tick-borne parasitic disease in the United States

Rates of babesiosis, a tick-borne parasitic disease, increased an average of 9% per year in the United States between 2015 and 2022 and four in 10 patients were found to be co-infected with another tick-borne illness such as Lyme disease, according to a new study led by researchers at Penn State Health Milton S. Hershey Medical Center and Penn State College of Medicine.

8 Oct 2024

Replicating Lewy body formation in living neurons to understand Parkinson's disease

Lewy bodies are a hallmark of Parkinson's disease (PD) and other related neurological conditions. Understanding why and how they develop is critical to developing better treatments.

8 Oct 2024

Study reveals limitations of ChatGPT in emergency medicine

If ChatGPT were cut loose in the Emergency Department, it might suggest unneeded x-rays and antibiotics for some patients and admit others who didn't require hospital treatment, a new study from UC San Francisco has found.

8 Oct 2024

CBT app shows promise in preventing depression

A cognitive behavioral therapy (CBT) app has been found to significantly prevent increases in depression in young people who are at high risk - and could be implemented as a cost-effective public mental health measure.

8 Oct 2024

What’s new and what to watch for in the upcoming ACA open enrollment period

It's that time of year again: In most states, the Affordable Care Act's annual open enrollment season for health plans begins Nov. 1 and lasts through Jan. 15.

8 Oct 2024

Brainstem inflammation may explain long Covid symptoms

Damage to the brainstem – the brain's 'control center' – is behind long-lasting physical and psychiatric effects of severe Covid-19 infection, a study suggests.

8 Oct 2024

Study suggests humans are approaching a biological limit to life

We've seen dramatic increases in life expectancy over the 19th and 20th centuries, thanks to healthier diets, medical advances and many other quality-of-life improvements.

8 Oct 2024

Unexpected benzene levels in popular acne and rosacea products

Investigators have determined that a substantial portion of topical benzoyl peroxide (BPO) acne and rosacea treatments currently on the market are unstable and contain unacceptably high levels of benzene, a known human carcinogen.

7 Oct 2024

Low-income Medicare Advantage beneficiaries face barriers to dental, vision and hearing care

Lower-income adults with Medicare Advantage plans are more likely to have difficulty paying for dental, vision, and hearing services than higher-income beneficiaries - despite enrolling in plans that cover these benefits, according to a new study published in Health Affairs.

7 Oct 2024