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Large analysis identifies 579 genetic locations linked to anti-social behavior and addiction

An analysis of data from 1.5 million people has identified 579 locations in the genome associated with a predisposition to different behaviors and disorders related to self-regulation, including addiction and child behavioral problems.

27 Aug 2021

Adding berzosertib to standard treatment for metastatic urothelial cancer does not extend patient survival

A Phase 2 trial led by City of Hope, a world-renowned research and treatment center for cancer and diabetes, suggests that adding the novel ataxia telangiectasia and Rad3-related (ATR) inhibitor drug berzosertib to standard-of-care chemotherapy for patients with metastatic urothelial cancer does not extend progression-free survival.

27 Aug 2021

Researchers show how to personalize treatments for patients with COPD

Patients with COPD are treated with drugs to improve the breathing ability in combination with inhaled corticosteroids to reduce the risk of acute worsening of the lung conditions.

26 Aug 2021

Study uncovers epigenetic mechanisms that promote glioma tumor growth

Northwestern Medicine investigators have discovered the epigenetic mechanisms involved in the regulation of multiple oncogenes in glioma cells, mechanisms that promote overall glioma tumor growth and resistance to therapy, according to a study published in the journal Clinical Cancer Research.

25 Aug 2021

New AHA statement provides guidance about cardiovascular genetic testing in children

Cardiovascular genetic testing in children presents unique challenges, requiring pre- and post-test counseling with an individualized approach for families.

20 Aug 2021

3D-printed tumors potentially next step in personalized medicine

Scientists at Tel Aviv University have successfully printed an entire active and viable brain tumor using a three-dimensional or 3D printer for the first time.

20 Aug 2021

Study identifies the cause and treatment for rare rheumatoid-like autoinflammatory condition

The absence of a protein that activates the body's antiviral defenses can cause a rare rheumatoid-like autoinflammatory condition that is treatable with an FDA-approved class of drugs known as TNF (tumor necrosis factor) inhibitors, a global research team led by Mount Sinai has found.

19 Aug 2021

MD Anderson receives nearly $13 million from CPRIT to support research efforts

The University of Texas MD Anderson Cancer Center has been awarded $12.75 million from the Cancer Prevention and Research Institute of Texas to support basic, clinical, translational and prevention research efforts, including $3 million for a new project to build clinical trial network infrastructure across Texas.

19 Aug 2021

Studies shed light on the versatility, precision, and sensitivity of quantitative analytical tools

Three independent studies in the Journal of Pharmaceutical Analysis explore the potential uses and applications of quantitative analytical tools in the characterization and quality assessment of biological and medicinal compounds.

19 Aug 2021

Researchers create the first 3D-bioprinted model of active glioblastoma tumor

A scientific achievement for researchers at Tel Aviv University: printing an entire active and viable glioblastoma tumor using a 3D printer.

18 Aug 2021

CRISPR screening tool pinpoints new therapeutic target to treat acute myeloid leukemia

A CRISPR screening tool identified a new therapeutic target to treat acute myeloid leukemia (AML) that has the potential to leave patients with fewer side effects than current approaches, according to a new study from Penn Medicine published online in Molecular Cell.

18 Aug 2021

New assay using fresh uncultured lung tumor cells could guide personalized treatments

A new study from the University of Helsinki shows that cells that are freshly isolated from lung cancers can be used to create robust drug response data. This approach can identify actionable or non-responsive treatments, illustrated by a case study in which the assay was used to guide the compassionate treatment of a patient.

18 Aug 2021

Study suggests Harmony COVID-19 assay is superior to laboratory-based tests

A new study suggests a new coronavirus test developed by scientists from the University of Washington and the Brotman Baty Institute for Precision Medicine produces faster and more sensitive results than conventional PCR tests to measure severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral RNA.

18 Aug 2021

Blue light can activate key signaling pathway that plays role in embryonic development and cancer

Blue light is illuminating new understanding of a key signaling pathway in embryo development, tissue maintenance and cancer genesis.

17 Aug 2021

Specific leukemia gene mutations exert divergent effects on DNA repair and sensitivity to PARP Inhibitors

In a recent study published in Cancer Research, researchers from Fels Cancer Institute for Personalized Medicine at the Lewis Katz School of Medicine at Temple University and Fox Chase Cancer Center identified specific leukemia gene mutations and the mechanisms by which they regulate DNA repair and respond to PARP inhibitors.

13 Aug 2021

Targeting a skin protein may reduce the severity of psoriasis, study reveals

Results from a Michigan Medicine study reveal that targeting a protein found in the skin may reduce the severity of psoriasis.

12 Aug 2021

Researchers to study the genomics of Alzheimer's disease in people with African heritage

Researchers at the Case Western Reserve University School of Medicine, with colleagues from the John P. Hussman Institute for Human Genomics at the University of Miami, Taub Institute for Research on Alzheimer's Disease and the Aging Brain, at Columbia University, and Wake Forest University School of Medicine will study the genomics of Alzheimer's disease (AD) in people with African heritage throughout the United States.

12 Aug 2021

Researchers aim to identify gene-lifestyle interactions that contribute to cardiometabolic disease risk

Researchers at Washington University School of Medicine in St. Louis have received a four-year, $8.8 million grant to ramp up research aimed at unraveling how an individual's risks of cardiometabolic diseases, such as heart disease and Type 2 diabetes, are influenced by the interaction of specific genes with demographic and lifestyle factors.

11 Aug 2021

Researchers employ artificial intelligence models for image-based detection of COVID-19

Medical imaging has long been a vital tool for the diagnosis and prognostic assessments of many diseases. In recent years, the use of artificial intelligence models has been used in conjunction with this imaging to augment their diagnostic capabilities.

11 Aug 2021

New approach could be a useful tool in the fight against cancer drug resistance

Using a virus to purposely mutate genes that produce cancer-driving proteins could shed light on the resistance that inevitably develops to cancer drugs that target them, a new study led by UT Southwestern scientists suggests.

10 Aug 2021

Precision Medicine News and Research

Large analysis identifies 579 genetic locations linked to anti-social behavior and addiction

Adding berzosertib to standard treatment for metastatic urothelial cancer does not extend patient survival

Researchers show how to personalize treatments for patients with COPD

Study uncovers epigenetic mechanisms that promote glioma tumor growth

New AHA statement provides guidance about cardiovascular genetic testing in children

3D-printed tumors potentially next step in personalized medicine

Study identifies the cause and treatment for rare rheumatoid-like autoinflammatory condition

MD Anderson receives nearly $13 million from CPRIT to support research efforts

Studies shed light on the versatility, precision, and sensitivity of quantitative analytical tools

Researchers create the first 3D-bioprinted model of active glioblastoma tumor

CRISPR screening tool pinpoints new therapeutic target to treat acute myeloid leukemia

New assay using fresh uncultured lung tumor cells could guide personalized treatments

Study suggests Harmony COVID-19 assay is superior to laboratory-based tests

Blue light can activate key signaling pathway that plays role in embryonic development and cancer

Specific leukemia gene mutations exert divergent effects on DNA repair and sensitivity to PARP Inhibitors

Targeting a skin protein may reduce the severity of psoriasis, study reveals

Researchers to study the genomics of Alzheimer's disease in people with African heritage

Researchers aim to identify gene-lifestyle interactions that contribute to cardiometabolic disease risk

Researchers employ artificial intelligence models for image-based detection of COVID-19

New approach could be a useful tool in the fight against cancer drug resistance

Event guide: The 4th Precision Medicine in Inflammatory Bowel Disease Summit eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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