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Cedars-Sinai surgeons detect and remove 25-pound cancerous ovarian tumor

Maria Robles Garcia was sure her uncomfortable abdominal symptoms weren't caused by irritable bowel syndrome or from being overweight, no matter that her local doctors repeatedly told her that was the case.

13 Nov 2019

Tips to help parents share family health history with children

Parents spend hours planning to talk with their children about the "birds and bees." But moms and dads often ignore an equally important conversation - discussing their family's overall health history.

13 Nov 2019

Study explains how variation in spinal patterns may lead to scoliosis

A pediatric researcher has identified patterns of spinal curvature in younger children that may be likely to develop into scoliosis by adolescence.

13 Nov 2019

Children's National receives new funding to strengthen global polycystic kidney disease initiative

Lisa M. Guay-Woodford, M.D., McGehee Joyce Professor of Pediatrics at Children's National Hospital, has received a $5.7 million dollar gift to support clinical and research activities.

13 Nov 2019

Deterministic mechanoporation of cells en masse to cure cancer

What if you could cure cancer by re-engineering patients' cells to better target and destroy their own tumors? With the advent of powerful new cellular engineering technologies, this is no longer the stuff of science fiction.

13 Nov 2019

Tall people more likely to develop atrial fibrillation

Size may matter when it comes to having a safe and steady heart. A new study shows tall people are more likely to develop from an irregular heartbeat, known as atrial fibrillation (AFib).

13 Nov 2019

New method could optimize facial analysis to detect genetic syndromes

Each year, over a million children are born with a genetic disease. Although about half of genetic syndromes present facial dysmorphology, abnormal facial features are often subtle at birth and their identification by paediatricians can prove challenging. Delays and errors in diagnosis have a significant impact on mortality and morbidity associated with genetic syndromes.

13 Nov 2019

Tulane virus needs intracellular calcium to replicate

Some gastrointestinal viruses need calcium. They need calcium ions to carry out several essential aspects of viral life, such as entry into host cells, genome replication and building new viruses to invade other cells. The cells invaded by viruses also use calcium. They use it as signals to regulate many of the cells' own processes, but viruses can takeover cellular calcium signaling to satisfy their own needs.

13 Nov 2019

Researchers develop novel mathematical framework for mapping out drug interaction

Combining two or more drugs can be an effective treatment of diverse diseases, such as cancer. Yet, at the same time, the wrong drug combination can cause major side effects. Currently there is no systematic understanding of how different drugs influence each other. Thus, elucidating how two given drugs interact, and whether they have a beneficial effect, would mean a major step towards drug development to treat diseases more effectively in the future.

13 Nov 2019

Leukemia type B cell can transform into a macrophage through epigenetic changes

All the tissues of our body have the same DNA, but they perform very different functions and have very different aspects.

13 Nov 2019

Height may be a causal risk factor for atrial fibrillation

Taller people have an increased risk of developing atrial fibrillation (AFib), an irregular and often rapid heartbeat that can lead to stroke, heart failure and other complications, according to a new Penn Medicine study.

13 Nov 2019

Stress affects circadian rhythm, increases metabolic disease risk

Stress is a normal part of life, but too much of everything isn’t healthy. Every day, people from all walks of life experience stress of various degrees. A new study found that when stress has disrupted the circadian rhythm, the body’s internal clock, it can increase the risk of developing metabolic diseases.

12 Nov 2019

Resistant schizophrenia associated with low IQ and family history

According to a new study published on November 12, 2019, in the journal Molecular Psychiatry, individuals with schizophrenia resistant to treatment are more likely to have a family history and a lower IQ compared to other schizophrenic patients. This finding could help design more effective therapies for this subgroup of patients, as for instance, drugs that improve mental processes.

12 Nov 2019

New AI-driven approach for single blood cell classification

For the first time, researchers from Helmholtz Zentrum München and the University Hospital of LMU Munich show that deep learning algorithms perform similar to human experts when classifying blood samples from patients suffering from acute myeloid leukemia.

12 Nov 2019

Cardiac-specific biomarkers may help predict CVD risk factors early

A new review article provides valuable insights into how traditional and emerging cardiac-specific biomarkers and their associated cardiovascular disease (CVD) risk factors may help point to effective preventive interventions in high-risk obese populations starting at an early stage of disease development.

12 Nov 2019

Collaborative study shows sex-specific processes in schizophrenia and bipolar disorder

Recent studies have found a high genetic similarity of the psychiatric diseases schizophrenia and bipolar disorder, whose disease-specific changes in brain cells show an overlap of more than 70 percent.

12 Nov 2019

New study sounds a note of caution in using probiotics in ICU

It's become common for patients in the intensive care unit (ICU), both children and adults, to receive probiotics. Often, they are started at home to counteract diarrhea caused by antibiotics. There is also interest in using probiotics proactively in the ICU. A large multicenter clinical trial in Canada is testing whether probiotics would prevent ventilator-associated pneumonia in adult ICU patients.

12 Nov 2019

Scientists identify new mechanism for the development of Parkinson's disease

An international research team including scientists from the University of Cologne have identified a new mechanism for the development of Parkinson's disease, which could prove to be the starting point for the development of a more targeted therapy.

12 Nov 2019

Two strains of the same bacterium work together to cause deadly flesh-eating disease

Two different strains of the same flesh-eating bacteria species work in combination to become more dangerous.

12 Nov 2019

Polygenic risk score improves psychosis risk prediction, study finds

A new study led by researchers at the University of North Carolina at Chapel Hill has found that that using a polygenic risk score based on data from genome-wide association studies improves psychosis risk prediction in persons meeting clinical high-risk criteria.

12 Nov 2019