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New treatment combination shows promise for metastatic colorectal cancer patients with rare genetic mutation

An international Phase 3 clinical trial found that metastatic colorectal cancer patients with a rare genetic tumor mutation called KRAS G12C experienced superior progression-free survival rates compared to standard of care when offered a combination treatment of KRAS inhibitor sotorasib and monoclonal antibody panitumumab.

27 Oct 2023

Breast cancer screening trial expands internationally to enhance diversity

A clinical trial led by the ECOG-ACRIN Cancer Research Group (ECOG-ACRIN) demonstrates how diversity among study participants is vital for reducing outcomes disparities.

27 Oct 2023

Long COVID prevalence high in Scandinavians with severe COVID-19

A collaborative study involving researchers from Karolinska Institutet has charted the prevalence of severe physical symptom burden amongst Scandinavians for up to two years after a SARS-CoV-2 infection.

27 Oct 2023

Watch: California and feds invest in health care for homeless people

KFF Health News senior correspondent Angela Hart appeared on Spectrum News 1's "Los Angeles Times Today" on Oct. 24 to discuss her coverage of state and federal efforts to expand street medicine — a growing field that focuses on treating homeless people wherever they are, whether indoors or on the streets.

27 Oct 2023

Microbubble-based biomarker could improve NIR-PIT treatment for cancer

Researchers at Nagoya University in Japan and their collaborators have used a biomarker based on microbubbles to evaluate the success of near-infrared photoimmunotherapy (NIR-PIT) treatment.

26 Oct 2023

AI-designed drug candidate shows promise for gastric acid inhibition

Researchers at Nagoya University in Japan created and improved artificial intelligence (AI) designs to synthesize a candidate compound for a new gastric acid inhibitor with a better binding affinity than existing drugs.

26 Oct 2023

Fluoride exposure in drinking water linked to cognitive deficits in children

Long-term consumption of water with fluoride levels far above established drinking water standards may be linked to cognitive impairments in children, according to a new pilot study from Tulane University.

26 Oct 2023

Brain injury expert calls for reforms to legal definition of death in the United States

After surveying the views expressed by 41 advocacy, medical, and transplant-focused organizations on the Uniform Determination of Death Act, a brain injury expert is calling for much-needed reforms to the legal definition of death in the United States.

26 Oct 2023

City of Hope, TGen receive $4.5 million to validate liquid biopsy for early detection of pancreatic cancer

City of Hope, one of the largest cancer research and treatment organizations in the United States, and TGen are leading an international group that has been awarded $4.5 million to validate a liquid biopsy for the early detection of pancreatic cancer.

26 Oct 2023

AI shows promise in predicting type 2 diabetes but faces hurdles for clinical use

Researchers have conducted a comprehensive review of AI-based models for predicting type 2 diabetes, revealing their potential for individualized risk assessment and preventative care. Despite promising results, the study calls for more extensive validation and collaboration between AI and medical experts for effective clinical application.

26 Oct 2023

Dato-DXd improves progression-free survival in patients with metastatic non-squamous NSCLC

Treatment with datopotamab deruxtecan (Dato-DXd), a novel Trop-2 directed antibody-drug conjugate, was found to significantly improve progression-free survival in patients with metastatic non-small cell lung cancer, an improvement that was primarily driven by patients with non-squamous tumors.

26 Oct 2023

Researchers receive $1.5 million grant to develop VR assessment system for TBI

One of the most common injuries sustained by military personnel in recent conflicts has been traumatic brain injury, or TBI.

26 Oct 2023

New study challenges long-held belief about how chemotherapy works

A new study from the University of Wisconsin–Madison suggests that chemotherapy may not be reaching its full potential, in part because researchers and doctors have long misunderstood how some of the most common cancer drugs actually ward off tumors.

26 Oct 2023

Exploring the link between red meat intake and inflammation

Inflammation is a risk factor for many chronic diseases, including cardiovascular disease (CVD), and the impact of diet on inflammation is an area of growing scientific interest.

26 Oct 2023

Endometriosis and irritable bowel syndrome share genetic risk factors, UQ research shows

University of Queensland researchers have shown that endometriosis and irritable bowel syndrome (IBS) share genetic risk factors, explaining why patients with one condition may also have the other.

26 Oct 2023

Researchers to develop machine models to predict cardiometabolic risks in young people

A researcher at Binghamton University, State University of New York will lead a $2.5 million project from the National Institutes of Health to develop machine models to identify and predict cardiometabolic risks in adolescents and young adults.

26 Oct 2023

Newly identified amino acid may play key role in predicting outcomes and treatment of long COVID

University of Alberta researchers have identified an amino acid that may play a key role in predicting poor clinical outcomes and the treatment of long COVID.

26 Oct 2023

$3.4 million grant awarded to identify therapeutic treatments for acute respiratory distress syndrome

A four-year, $3.4 million grant to investigate molecular mechanisms and therapeutic treatments for acute respiratory distress syndrome (ARDS) has been awarded to UTHealth Houston researchers by the National Heart, Lung, and Blood Institute, part of the National Institutes of Health.

26 Oct 2023

Genomic screening encourages people with hemochromatosis to seek treatment and relevant management

Genomic screening to identify hemochromatosis - a disorder that causes iron levels in the body to rise to dangerous levels - encourages people with the condition to seek treatment and ongoing management, a Geisinger study found.

26 Oct 2023

Treatment in ambulance-based mobile stroke unit increases the likelihood of averting strokes

Receiving a clot-busting drug in an ambulance-based mobile stroke unit (MSU) increases the likelihood of averting strokes and complete recovery compared with standard hospital emergency care, according to researchers at Weill Cornell Medicine, NewYork-Presbyterian, UTHealth Houston, Memorial Hermann-Texas Medical Center and five other medical centers across the United States.

26 Oct 2023

Medicine News and Research

New treatment combination shows promise for metastatic colorectal cancer patients with rare genetic mutation

Breast cancer screening trial expands internationally to enhance diversity

Long COVID prevalence high in Scandinavians with severe COVID-19

Watch: California and feds invest in health care for homeless people

Microbubble-based biomarker could improve NIR-PIT treatment for cancer

AI-designed drug candidate shows promise for gastric acid inhibition

Fluoride exposure in drinking water linked to cognitive deficits in children

Brain injury expert calls for reforms to legal definition of death in the United States

City of Hope, TGen receive $4.5 million to validate liquid biopsy for early detection of pancreatic cancer

AI shows promise in predicting type 2 diabetes but faces hurdles for clinical use

Dato-DXd improves progression-free survival in patients with metastatic non-squamous NSCLC

Researchers receive $1.5 million grant to develop VR assessment system for TBI

New study challenges long-held belief about how chemotherapy works

Exploring the link between red meat intake and inflammation

Endometriosis and irritable bowel syndrome share genetic risk factors, UQ research shows

Researchers to develop machine models to predict cardiometabolic risks in young people

Newly identified amino acid may play key role in predicting outcomes and treatment of long COVID

$3.4 million grant awarded to identify therapeutic treatments for acute respiratory distress syndrome

Genomic screening encourages people with hemochromatosis to seek treatment and relevant management

Treatment in ambulance-based mobile stroke unit increases the likelihood of averting strokes

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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