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Scientists break new ground with animal-free antibodies for diphtheria

A project taking the first steps towards ending the use of horses to treat diphtheria has succeeded.

21 Jan 2020

Drug profiling and gene editing method open new avenues in the development of CAR T-cell therapy

Researchers have discovered ways to boost CAR T-cell therapy.

21 Jan 2020

Patient-specific tumor organoids may one day be used to personalize cancer treatment

A patient-specific tumor organoid platform developed by Wake Forest Institute for Regenerative Medicine researchers and their cancer center colleagues could someday take the guessing game out of immunotherapy treatments.

21 Jan 2020

Magnetic nanomaterials may become the basis for new approach to treating liver fibrosis

A team of scientists from Immanuel Kant Baltic Federal University together with their colleagues from NUST MISiS and RWTH Aachen University (Germany) compared different treatments against liver fibrosis and published the results of their study in the Cells journal.

21 Jan 2020

Biophysicists shed light on the structure, functioning mechanism of CysLT receptors

Biophysicists from the MIPT Center for Molecular Mechanisms of Aging and Age-Related Diseases have teamed up with colleagues from Canada, the U.S., Japan, France, and Germany to shed light on the structure and functioning mechanism of the CysLT receptors, which regulate inflammatory responses associated with allergic disorders.

21 Jan 2020

Study finds new strategies for developing cancer drug

After years of research on cell surface receptors called Frizzleds, researchers at Karolinska Institutet in Sweden provide the proof-of-principle that these receptors are druggable by small molecules. The results, which are published in the scientific journal Nature Communications, open for new strategies to treat different types of cancer.

21 Jan 2020

NAU scientists study zebrafish to find powerful melanoma-fighting drugs

Melanoma is the most lethal type of skin cancer and unusually common in Arizona, where residents are exposed to higher-than-average amounts of ultraviolet radiation. However, Northern Arizona University scientists believe the formula for a combination of melanoma-fighting drugs is within reach.

21 Jan 2020

Antiviral compound from banana plants shows potential for clinical use against influenza

What keeps most infectious disease researchers up at night aren't infamous viruses like Ebola. Instead, influenza, commonly known as the flu, continues to be a clear and present danger to humanity.

21 Jan 2020

New technology systematically identifies drug targets in living animals

Developing new medicines and understanding how they target specific organs often gives a crucial advantage in the fight against human diseases.

21 Jan 2020

Turbine appoints new SAB members to guide its simulation-first drug discovery mission

Turbine, a simulation-first drug discovery company, today announced the formation of its Scientific Advisory Board with the appointments of Dr. Annalisa Jenkins, Dr. Mihriban Tuna, and Dr. Alan Barge.

21 Jan 2020

SITESEEKER to be used for Otsuka’s therapeutics discovery programs

PhoreMost will deploy its in-house expertise and next-generation phenotypic screening platform, SITESEEKER, in disease-relevant pathways nominated by Otsuka.

From PhoreMost 21 Jan 2020

Abdominal obesity linked to risk of recurrent heart attacks

Heart attack survivors who carry excess fat around their waist are at increased risk of another heart attack, according to research published today in the European Journal of Preventive Cardiology, a journal of the European Society of Cardiology.

20 Jan 2020

Medicinal cannabis may not alleviate sleep problems over the long term

Medicinal cannabis might not ease sleep problems in people with chronic pain over the long term, because frequent users might build up tolerance to its sleep-inducing effects, suggests preliminary research published online in BMJ Supportive & Palliative Care.

20 Jan 2020

Research suggests new approach to reducing the risk of sudden death in heart failure

Around 26 million people worldwide suffer from heart failure, with more than 50 per cent dying suddenly most likely due to the spontaneous onset of a heart rhythm problem, known as an arrhythmia.

20 Jan 2020

Certain enzymes implicated in diseases like cancer also destroy each other

Like motley bandits, certain enzymes implicated in cancer and other diseases also annihilate each other. A new study reveals details of their mutual foils in the hopes that these behaviors can be leveraged to fight the enzymes' disease potential.

20 Jan 2020

Novel drug inhibits liver damage, obesity and glucose intolerance in mice fed with high-fat diet

Mice given a new drug targeting a key gene involved in lipid and glucose metabolism could tolerate a high-fat diet regimen (composed of 60% fat from lard) without developing significant liver damage, becoming obese, or disrupting their body's glucose balance.

20 Jan 2020

Study uncovers anticancer potential of many non-oncology drugs

Drugs for diabetes, inflammation, alcoholism -- and even for treating arthritis in dogs -- can also kill cancer cells in the lab, according to a study by scientists at the Broad Institute of MIT and Harvard and Dana-Farber Cancer Institute.

20 Jan 2020

Enzymes that cannibalize each other and promote cancer

A new study to be published this week in the journal The Proceedings of the National Academy of Sciences in the week of January 20, 2020. shows that certain human enzymes play dual roles in health and disease. Not only do they promote the occurrence of cancer and some other illnesses, they also eliminate one another rather like cannibals. The researchers hope this behaviour can be exploited to prevent these enzymes from causing human disease.

20 Jan 2020

Alarming link between marijuana and increased heart risk

Marijuana use is rising steadily across the US as more and more states enact laws making it a legal recreational and medicinal agent. However, a new study underlines the fact that this is, in fact, playing with an unknown substance, which may cause serious bodily harm. The review article, published in the Journal of the American College of Cardiology, shows that more than 2 million adults who currently have heart or vascular disease gave a history of being currently on marijuana products, or having used them in the past.

20 Jan 2020

New uses for old medicines

It turns out that in the rush to invent new drugs to treat cancers, scientists may have overlooked some obvious possibilities of existing drugs currently being used for other diseases. A new study says that therapies for diabetes, inflammation and alcoholism, and even for dog arthritis, can also result in the successful killing of cancer cells in culture.

20 Jan 2020

Drugs News and Research

Scientists break new ground with animal-free antibodies for diphtheria

Drug profiling and gene editing method open new avenues in the development of CAR T-cell therapy

Patient-specific tumor organoids may one day be used to personalize cancer treatment

Magnetic nanomaterials may become the basis for new approach to treating liver fibrosis

Biophysicists shed light on the structure, functioning mechanism of CysLT receptors

Study finds new strategies for developing cancer drug

NAU scientists study zebrafish to find powerful melanoma-fighting drugs

Antiviral compound from banana plants shows potential for clinical use against influenza

New technology systematically identifies drug targets in living animals

Turbine appoints new SAB members to guide its simulation-first drug discovery mission

SITESEEKER to be used for Otsuka’s therapeutics discovery programs

Abdominal obesity linked to risk of recurrent heart attacks

Medicinal cannabis may not alleviate sleep problems over the long term

Research suggests new approach to reducing the risk of sudden death in heart failure

Certain enzymes implicated in diseases like cancer also destroy each other

Novel drug inhibits liver damage, obesity and glucose intolerance in mice fed with high-fat diet

Study uncovers anticancer potential of many non-oncology drugs

Enzymes that cannibalize each other and promote cancer

Alarming link between marijuana and increased heart risk

New uses for old medicines

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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