Protein C News and Research

RSS

Researchers receive £230,000 to develop world's first smart vaccine device

Researchers at Swansea University have received £230,000 to develop the world's first smart vaccine device that will both deliver the COVID-19 vaccine and measure its efficacy through monitoring the body's associated response.

6 Jan 2021

Using a blood test to predict Alzheimer's disease risk during symptom-free stage

Using a blood test, a German-Dutch research team has predicted the risk of Alzheimer's disease in people who were clinically diagnosed as not having Alzheimer's disease but who perceived themselves as cognitively impaired (Subjective Cognitive Declined, SCD).

6 Jan 2021

Scientists develop a new method to study the molecular characteristics of T cells

UT Southwestern scientists have developed a new method to study the molecular characteristics of T cells, critical immune cells that recognize and attack invaders in the body such as viruses, bacteria, and cancer.

6 Jan 2021

Researchers identify the missing link between intestinal disease and brain injury in premature infants

Physicians have long known that necrotizing enterocolitis (NEC), a potentially lethal inflammatory condition that destroys a premature infant's intestinal lining, is often connected to the development of severe brain injury in those infants who survive.

6 Jan 2021

Disulfide-reducing agents demonstrate potential antiviral activity against SARS-CoV-2

Researchers recently demonstrated that chemical agents capable of reducing disulfide (S-S) bonds can be potentially used as antiviral drugs against SARS-CoV-2, the causative pathogen of COVID-19.

6 Jan 2021

Modified Vaccinia Ankara model vaccine prevents COVID-19 in transgenic mice study

A new study shows the effectiveness of a novel recombinant vaccinia virus that expresses modified SARS-CoV-2 spike antigen, in preventing the replication of the virus in the respiratory tract of transgenic mice, and to prevent lethal disease.

6 Jan 2021

Are SARS-CoV-2 antibodies associated with disease enhancement?

As SARS-CoV-2 continues to wreak its havoc, antibodies that neutralize the virus and protect against infection have become an important focus of research. However, there is a concern as to whether these antibodies can actually enhance the disease.

6 Jan 2021

Liver cancer cells cause stromal cells to secrete protein that enhances tumor growth

Hepatocellular carcinoma (HCC), frequently seen in patients with liver cirrhosis caused by alcohol abuse or chronic viral hepatitis, is the most common form of liver cancer worldwide.

6 Jan 2021

Researchers claim SARS-CoV-2 B.1.1.7 variant likely to become globally dominant

The new variant of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) detected in England replicates more than two times faster than the earlier strains. This replication advantage promises to make it the dominant global variant very shortly. This finding comes from a startling preprint that appeared on the medRxiv* server in December 2020.

6 Jan 2021

New mathematical model proposes optimal treatment strategies for COVID-19

Getting control of COVID-19 will take more than widespread vaccination; it will also require a better understanding of why the disease causes no apparent symptoms in some people but leads to rapid multi-organ failure and death in others, as well as better insight into what treatments work best and for which patients.

5 Jan 2021

Study: Decreased activation of LEF1 gene disrupts ordinary neuronal function

Lithium is considered the gold standard for treating bipolar disorder (BD), but nearly 70 percent of people with BD don't respond to it.

5 Jan 2021

Glycyrrhizin in licorice root neutralizes SARS-CoV-2 in vitro by inhibiting the main protease Mpro

In a recent bioRxiv* preprint paper, researchers from Germany analyzed aqueous licorice root extract for its neutralizing activity against SARS-CoV-2 in vitro. They identified glycyrrhizin, the primary active ingredient in the root, and revealed the underlying mechanism of viral neutralization.

5 Jan 2021

Researchers discover new metabolic vulnerability in a highly aggressive form of lung cancer

Researchers at the Children's Medical Center Research Institute at UT Southwestern (CRI) have discovered a new metabolic vulnerability in a highly aggressive form of non-small cell lung cancer (NSCLC).

5 Jan 2021

Inhibition of blood clotting factor reduces the formation of brain metastases in mice

Brain metastases can only develop if cancer cells first exit the fine blood vessels and enter into the brain tissue.

5 Jan 2021

$Loss of critical enzymatic processes can increase bone fracture risk$

Loss of critical enzymatic processes can increase bone fracture risk

A loss of enzymatic processes within the body can increase a person's risk of bone fracture. This new insight was recently published in eLife by an international team of scientists and engineers led by Deepak Vashishth, the director of the Center for Biotechnology and Interdisciplinary Studies at Rensselaer Polytechnic Institute.

5 Jan 2021

SARS-CoV-2 infected alveolar type-II lung cells show senescence

Using monoclonal antibodies against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein and senescent markers, researchers provide evidence that virus-infected lung cells acquire characteristics of cellular senescence, which also leads to expression of proinflammatory cytokines.

5 Jan 2021

Researchers develop detailed map of protein-protein interactions between SARS-CoV-2 and the host

By conducting a state-of-the-art interactome study between SARS-CoV-2 and host cells, researchers from the University of Texas MD Anderson Cancer Center in Houston identified 437 human proteins as the high-confidence interacting proteins – with substantial implications for understanding coronavirus disease 2019 (COVID-19) pathology and potential treatments.

5 Jan 2021

Researchers resolve mysteries about the function of key gene-silencing protein

A long-running debate over how an important gene-silencing protein identifies its targets has been resolved by researchers at Massachusetts General Hospital (MGH).

4 Jan 2021

Researchers discover protein crucial to T cell metabolism and anti-tumor immune response

Researchers at The University of Texas MD Anderson Cancer Center have discovered that a protein called NF-kappa B-inducing kinase (NIK) is essential for the shift in metabolic activity that occurs with T cell activation, making it a critical factor in regulating the anti-tumor immune response.

4 Jan 2021

USF researchers discover promising new compound to open constricted airways

Despite the progress made in managing asthma and chronic obstructive pulmonary disease (COPD), poorly controlled symptoms for both respiratory diseases can lead to severe shortness of breath, hospitalizations or even death.

4 Jan 2021

Protein C News and Research

Researchers receive £230,000 to develop world's first smart vaccine device

Using a blood test to predict Alzheimer's disease risk during symptom-free stage

Scientists develop a new method to study the molecular characteristics of T cells

Researchers identify the missing link between intestinal disease and brain injury in premature infants

Disulfide-reducing agents demonstrate potential antiviral activity against SARS-CoV-2

Modified Vaccinia Ankara model vaccine prevents COVID-19 in transgenic mice study

Are SARS-CoV-2 antibodies associated with disease enhancement?

Liver cancer cells cause stromal cells to secrete protein that enhances tumor growth

Researchers claim SARS-CoV-2 B.1.1.7 variant likely to become globally dominant

New mathematical model proposes optimal treatment strategies for COVID-19

Study: Decreased activation of LEF1 gene disrupts ordinary neuronal function

Glycyrrhizin in licorice root neutralizes SARS-CoV-2 in vitro by inhibiting the main protease Mpro

Researchers discover new metabolic vulnerability in a highly aggressive form of lung cancer

Inhibition of blood clotting factor reduces the formation of brain metastases in mice

Loss of critical enzymatic processes can increase bone fracture risk

SARS-CoV-2 infected alveolar type-II lung cells show senescence

Researchers develop detailed map of protein-protein interactions between SARS-CoV-2 and the host

Researchers resolve mysteries about the function of key gene-silencing protein

Researchers discover protein crucial to T cell metabolism and anti-tumor immune response

USF researchers discover promising new compound to open constricted airways

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Latest News