Chloroquine News and Research

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Zero benefit of Hydroxychloroquine or Chloroquine in COVID-19, says extensive study

The purported "game-changer" anti-malarial drug Hydroxychloroquine, which was claimed to be effective in preventing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and also helping better outcomes in COVID-19 patients, seems to have failed in clinical trials.

25 May 2020

Treatment with chloroquine or hydroxychloroquine offers no benefit for COVID-19 patients

A large observational study suggests that treatment with the antimalarial drug chloroquine or its analog hydroxychloroquine (taken with or without the antibiotics azithromycin or clarithromycin) offers no benefit for patients with COVID-19.

22 May 2020

Study evaluates the effectiveness of interferon beta 1b in COVID-19 pneumonia

As the world struggles to overcome the current COVID-19 pandemic with non-pharmacological interventions, in the absence of an effective drug or vaccine, existing immunomodulators are being repurposed. A new study published on the preprint server medRxiv* in May 2020 shows no clinical benefit to the use of one such drug, called interferon beta 1b (IFN beta1b).

22 May 2020

Global study to test whether antimalaria drug can prevent COVID-19 in health-care workers

With $9 million in philanthropic support, an international group of physicians and scientists is establishing a research network to evaluate promising therapies for COVID-19.

18 May 2020

COVID-19 clinical trials show positive early results, says GlobalData

With the number of COVID-19 cases and deaths increasing with each passing day, the need for a therapeutic or a vaccine for the pandemic intensifies.

18 May 2020

Chasing the elusive dream of a COVID cure

Although scientists and stock markets have celebrated the approval for emergency use of remdesivir to treat COVID-19, a cure for the disease that has killed nearly 260,000 people remains a long way off — and might never arrive.

15 May 2020

NIH begins clinical study to evaluate hydroxychloroquine and azithromycin for COVID-19

A clinical trial has begun to evaluate whether the malaria drug hydroxychloroquine, given together with the antibiotic azithromycin, can prevent hospitalization and death from coronavirus disease 2019 (COVID-19).

14 May 2020

Drug counterfeiters are using corona pandemic to make profits in Africa

Drug counterfeiters are using the corona pandemic to make profits in Africa selling completely ineffective or even harmful medicines.

14 May 2020

A 'multi-omics' approach to the development of drugs against COVID-19

A new study published on the preprint server medRxiv* in May 2020 reports a multi-omics approach that could make it easier to develop drugs that are effective against COVID-19.

12 May 2020

Experts advise not to make COVID-19 crisis worse by rushing for cures

People have died from overdoses of unproven cures in past pandemics. In an editorial published today in Australian Prescriber, Associate Professor Darren Roberts from St Vincent’s Hospital in Sydney and Dr Alexandra Bennett from the NSW Therapeutic Advisory Group advise we should not make the current COVID-19 crisis worse by using medicines based on inadequate evidence.

11 May 2020

KHN’s ‘What the Health?’: Blowing the whistle on Trump team’s COVID policies

Those working inside the Trump administration are getting so frustrated with the response to the COVID-19 pandemic that they are going public.

8 May 2020

Study provides evidence for safety and efficacy of chloroquine in COVID-19

After a pilot study (Huang et al.Journal of Molecular Cell Biology, in press), having proved the safety and effectiveness of the drug to reduce the viral RNA to undetectable levels in 10 COVID-19 patients, the researchers began this current study, published on the preprint server medRxiv.

5 May 2020

Hydroxychloroquine shown to slow recovery for COVID-19 patients

As researchers try to piece together a therapeutic strategy against the ongoing COVID-19 pandemic, a recent retrospective study from Cleveland Clinic Abu Dhabi, assessed the Hydroxychloroquine's efficacy in increasing SARS-CoV-2 viral clearance, finding that it appeared to significantly slow viral clearance in mild to moderately ill COVID-19 patients.

5 May 2020

Hydroxychloroquine combined with azithromycin and abnormal heart rhythms in COVID-19 patients

A new study shows that the initially lauded combination of drugs against COVID-19 - Hydroxychloroquine and Chloroquine combined with azithromycin, could lead to abnormal and life-threatening heart rhythms. In patients hospitalized with the novel coronavirus infection or SARS CoV-2, this combination can lead to prolonged QT interval as can be detected on ECG.

3 May 2020

Pharmacy experts urge caution against use of antimalarial drugs to cure COVID-19

PHARMACY experts at the University of Huddersfield are urging caution over claims that widely-available antimalarial drugs could be a "magic bullet" to prevent and cure COVID-19. And the medicines can - if used rashly - have serious side effects.

30 Apr 2020

As coronavirus strikes, crucial data in electronic health records hard to harvest

When President Donald Trump started touting hydroxychloroquine as "one of the biggest game changers” for treating COVID-19, researchers hoped electronic health records could quickly tell them if he was on the right track.

30 Apr 2020

Online searches for unproven therapies for COVID-19

A new observational study by a group of scientists explores the rise in the public's fear-driven interest in unproven therapies for COVID-19, particularly chloroquine and hydroxychloroquine, by tracking the internet searches relating to the purchase of drugs in news reports or publicized by public figures. They conclude: "Stay grounded in evidence and fight misinformation." The research letter and accompanying editorial comment are published in the journal JAMA Internal Medicine.

29 Apr 2020

Chloroquine News and Research

Zero benefit of Hydroxychloroquine or Chloroquine in COVID-19, says extensive study

Treatment with chloroquine or hydroxychloroquine offers no benefit for COVID-19 patients

Study evaluates the effectiveness of interferon beta 1b in COVID-19 pneumonia

Global study to test whether antimalaria drug can prevent COVID-19 in health-care workers

COVID-19 clinical trials show positive early results, says GlobalData

Chasing the elusive dream of a COVID cure

NIH begins clinical study to evaluate hydroxychloroquine and azithromycin for COVID-19

Drug counterfeiters are using corona pandemic to make profits in Africa

A 'multi-omics' approach to the development of drugs against COVID-19

Experts advise not to make COVID-19 crisis worse by rushing for cures

KHN’s ‘What the Health?’: Blowing the whistle on Trump team’s COVID policies

Study provides evidence for safety and efficacy of chloroquine in COVID-19

Hydroxychloroquine shown to slow recovery for COVID-19 patients

Hydroxychloroquine combined with azithromycin and abnormal heart rhythms in COVID-19 patients

Pharmacy experts urge caution against use of antimalarial drugs to cure COVID-19

As coronavirus strikes, crucial data in electronic health records hard to harvest

Online searches for unproven therapies for COVID-19

Testing of hydroxychloroquine for COVID-19 begins at Montefiore And Einstein

How toxic are chloroquine and hydroxychloroquine to cells?

Shortage of coronavirus 'cure' puts pregnant lupus sufferers and their babies at risk

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