Chronic Pain News and Research

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Nerve injuries found to affect the entire immune system in unexpected ways

Nerve injuries can have long-lasting effects on the immune system that appear to differ between males and females, according to preclinical research from McGill University.

5 Nov 2025

Living near cannabis stores linked to more frequent use and less heavy drinking

A statewide study of more than 60,000 adult Oregonians shows that living near cannabis retail stores is associated with a greater tendency toward frequent cannabis use but a lower likelihood of heavy alcohol consumption.

4 Nov 2025

Molecular bumpers and glues rewire GPCR signaling for next-generation medicines

New research led by the University of Minnesota Medical School demonstrates that molecules acting as "molecular bumpers" and "molecular glues" can rewire G protein-coupled receptor (GPCR) signaling, turning the cell's busiest receptors into precision tools - opening the door to a new generation of safer, smarter medicines.

31 Oct 2025

Excess mortality associated with chronic pain can be avoided through spinal cord stimulation

Treating chronic neuropathic pain with spinal cord stimulation may help prevent excess mortality associated with chronic pain, a new study from the University of Eastern Finland and Kuopio University Hospital shows.

27 Oct 2025

New insight into TRPM3 heat sensor reveals how the body detects temperature

The ability to sense heat protects the body from burns and injury. But how the body actually feels temperature has remained an elusive mystery.

24 Oct 2025

Pain resilience affects physical activity independently of pain

Pain affects activity levels, but how individuals understand and act in the face of pain can make a difference, a new study from the University of Portsmouth has found.

23 Oct 2025

Foot or ankle injuries in professional football players may increase risk of osteoarthritis

A new paper in Rheumatology, published by Oxford University Press, finds that retired UK male professional football players who reported foot or ankle injuries during their careers were more likely to develop osteoarthritis in retirement.

22 Oct 2025

Botulinum toxin injections could be a powerful tool for treating post-amputation pain

Botulinum toxin injections provided greater short-term relief for phantom limb pain than standard medical and surgical care among Ukrainian war amputees, reports a new study led by Northwestern Medicine and Ukrainian physicians.

21 Oct 2025

$Anesthesiologist-led care speeds surgery and reduces complications for hip fracture patients$

Anesthesiologist-led care speeds surgery and reduces complications for hip fracture patients

When anesthesiologists lead the preoperative process, patients undergoing surgery for hip fractures - one of the leading causes of hospitalization in older adults - get to the operating room (OR) faster and have fewer complications, according to a study presented at the ANESTHESIOLOGY® 2025 annual meeting.

13 Oct 2025

Genetic study reveals links between cannabis use and mental health

University of California San Diego of Medicine researchers, in collaboration with the genetic testing company 23andMe, have identified regions of the human genome associated with cannabis use, uncovering new relationships with psychiatric, cognitive and physical health.

13 Oct 2025

Food insecurity and loneliness linked to higher risk of chronic pain after surgery

People who experience food insecurity or loneliness are much more likely to develop chronic pain after surgery, according to new research presented at the ANESTHESIOLOGY® 2025 annual meeting.

13 Oct 2025

Researchers uncover possible immune link to chronic pain

University of Arizona researchers may have uncovered a connection between chronic pain and a somewhat uncommon immune condition, opening the door to future research on immune biomarkers for chronic pain.

9 Oct 2025

Chiba University study clarifies molecular mechanism driving keloid's unpredictable growth

Keloids are raised, overgrown scars that can develop after skin injuries or surgery, often extending beyond the original wound boundaries. For many people, keloids are more than just a cosmetic concern; they often cause distressing symptoms such as chronic pain, itching, and restricted movement.

9 Oct 2025

New brain circuit discovery offers hope for chronic pain relief

Acute or short-lived pain, despite its bad reputation, is usually a lifesaver. It acts as a transient negative sensory experience that helps us avoid danger.

8 Oct 2025

Tramadol found to offer limited relief for chronic pain while raising risk of serious side effects

The strong opioid painkiller, tramadol, is not that effective at easing chronic pain for which it's widely prescribed, finds a pooled data analysis of the available research, published online in BMJ Evidence Based Medicine.

7 Oct 2025

Brain stimulation may help people with multiple sclerosis cut back on excessive cannabis use

A noninvasive device that delivers weak electrical currents to the brain may help those with multiple sclerosis cut back on excessive cannabis use, a new NYU Langone Health study of women with the condition shows.

7 Oct 2025

Penn Medicine study maps brain circuits impacted by psilocybin

Researchers at Penn Medicine have identified specific brain circuits that are impacted by psilocybin-the active compound found in some psychedelic mushrooms-which could lead to new paths forward for pain and mental health management options.

2 Oct 2025

Cannabis extract eases chronic back pain and improves quality of life in major clinical trial

A phase 3 trial in Nature Medicine found that a full-spectrum Cannabis sativa extract (VER-01) significantly reduced chronic low back pain and improved sleep and function compared with placebo. The extract was safe, well-tolerated, and showed no signs of abuse or dependence, with benefits maintained over long-term treatment.

30 Sep 2025

Healthy habits linked to younger brain age

Your chronological age may say 65, but your brain could be acting a decade younger - or older - depending on your life experiences.

25 Sep 2025

FAU study explores how a new drug may help treat PTSD and its common companions

About 12 million adults in the United States are affected by PTSD, impacting between 4% and 8% of the adult population – and up to 30% of military personnel and veterans.

24 Sep 2025

Chronic Pain News and Research

Nerve injuries found to affect the entire immune system in unexpected ways

Living near cannabis stores linked to more frequent use and less heavy drinking

Molecular bumpers and glues rewire GPCR signaling for next-generation medicines

Excess mortality associated with chronic pain can be avoided through spinal cord stimulation

New insight into TRPM3 heat sensor reveals how the body detects temperature

Pain resilience affects physical activity independently of pain

Foot or ankle injuries in professional football players may increase risk of osteoarthritis

Botulinum toxin injections could be a powerful tool for treating post-amputation pain

Anesthesiologist-led care speeds surgery and reduces complications for hip fracture patients

Genetic study reveals links between cannabis use and mental health

Food insecurity and loneliness linked to higher risk of chronic pain after surgery

Researchers uncover possible immune link to chronic pain

Chiba University study clarifies molecular mechanism driving keloid's unpredictable growth

New brain circuit discovery offers hope for chronic pain relief

Tramadol found to offer limited relief for chronic pain while raising risk of serious side effects

Brain stimulation may help people with multiple sclerosis cut back on excessive cannabis use

Penn Medicine study maps brain circuits impacted by psilocybin

Cannabis extract eases chronic back pain and improves quality of life in major clinical trial

Healthy habits linked to younger brain age

FAU study explores how a new drug may help treat PTSD and its common companions

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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