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Discovering Genetic Variants that Significantly Predispose People to Critical COVID-19

We speak with postdoctoral researcher Erola Pairo-Castineira about her recent work which aimed to find the genetic factors that may predispose individuals to critical COVID-19 and learn how COVID-19 affects cells in the body.

22 Apr 2022

Intranasal nanoparticle STING agonist with immunoantiviral activity against SARS-CoV-2 variants

Researchers developed an immunoantiviral, NanoSTING, and demonstrated its broad-spectrum antiviral properties in hamsters and mice.

21 Apr 2022

Researchers discover a novel signaling pathway that defines interferon responses in blood cancers

Northwestern Medicine investigators have discovered a novel signaling pathway activated by interferons, a group of immune system proteins, that suppresses the anti-tumor response of interferons in patients with a particular type of blood cancer, according to findings published in Nature Communications.

19 Apr 2022

Role of cGAS-STING in SARS-CoV-2 infection

A new study analyzes the activation of cGAS and STING can induce a type I IFN response due to SARS-CoV-2 infection.

15 Apr 2022

Study investigates the local-mucosal susceptibility and innate immune response to Omicron compared to other variants

A recent study observed that the replication of the SARS-CoV-2 Omicron variant was restricted in human lung tissues

5 Apr 2022

SARS-CoV-2 and pandemic chilblains

Researchers evaluate the pathophysiological relationship between COVID-19 and pandemic-associated chilblain lesions.

30 Mar 2022

Study evaluates the prevalence of autoantibodies targeting type I interferons in critically-ill COVID-19 patients

Researchers assessed the prevalence of antibodies that neutralize the type I interferon antiviral activity and reactivate herpesviruses such as herpes simplex virus types 1 and 2 and/or cytomegalovirus infections in patients with critical COVID-19.

24 Mar 2022

Rubella antibodies vs. COVID-19

A new study describes a potential relationship between antibody titers against the rubella virus and the severity of COVID-19.

22 Mar 2022

Novel genetic relationships with severe SARS-CoV-2

Researchers discovered multiple novel genetic processes underpinning severe COVID-19 using genome-wide association studies and meta-analyses.

11 Mar 2022

Relationship between immunological responses in the acute phase of SARS-CoV-2 infection and long-term cognitive deficits

A recent study reported that monocytosis during the acute phase of coronavirus disease 2019 could forecast anosognosia in long COVID.

8 Mar 2022

NETosis in COVID-19 and MIS-C

A new study investigates the role played by neutrophil extracellular traps formation and degradation in COVID-19.

7 Mar 2022

Assessing the potential of IFNa subtypes in suppressing SARS-CoV-2

A recent study analyzes IFNa subtypes for their therapeutic potential against SARS-CoV-2 and identified the underlying immune signatures and mechanisms.

3 Mar 2022

Triple drug regimen proven effective against non-structural protein-1 of SARS-CoV-2

Researchers evaluated the synergistic activity of drugs acting against non-structural protein 1 of SARS-CoV-2 to decrease the viral infectivity.

2 Mar 2022

Study finds lower prevalence of post-acute SARS-CoV-2 symptomology in vaccinated individuals

In a recent study, researchers evaluated the effect of COVID-19 vaccines on the symptomatic prevalence of SARS-CoV-2 infections beyond the acute phase of the disease.

28 Feb 2022

Research could pave the way for adoption of precision medicine approaches for COVID-19

The COVID-19 pandemic has revealed a frightening reality; the course of infection with this disease is highly variable. Some young patients have died from the virus, whereas several elderly people have survived without experiencing respiratory symptoms at all. Researchers are left wondering: why?

25 Feb 2022

Interferons News and Research

Discovering Genetic Variants that Significantly Predispose People to Critical COVID-19

Intranasal nanoparticle STING agonist with immunoantiviral activity against SARS-CoV-2 variants

Researchers discover a novel signaling pathway that defines interferon responses in blood cancers

Role of cGAS-STING in SARS-CoV-2 infection

Study investigates the local-mucosal susceptibility and innate immune response to Omicron compared to other variants

SARS-CoV-2 and pandemic chilblains

Study evaluates the prevalence of autoantibodies targeting type I interferons in critically-ill COVID-19 patients

Rubella antibodies vs. COVID-19

Novel genetic relationships with severe SARS-CoV-2

Relationship between immunological responses in the acute phase of SARS-CoV-2 infection and long-term cognitive deficits

NETosis in COVID-19 and MIS-C

Assessing the potential of IFNa subtypes in suppressing SARS-CoV-2

Triple drug regimen proven effective against non-structural protein-1 of SARS-CoV-2

Study finds lower prevalence of post-acute SARS-CoV-2 symptomology in vaccinated individuals

Research could pave the way for adoption of precision medicine approaches for COVID-19

Lung microbiome alterations and secondary-infections in lethal COVID-19

Spectrum of autoantibodies linked to autoimmune diseases in patients with different COVID-19 clinical outcomes

Mouse-adapted virus model to study persistent COVID induced lung disease

Features of platelet-immune crosstalk in healthy recipients of two doses of mRNA-based SARS-CoV-2 vaccine BNT162b2

Research highlights the need to include diverse populations in immunogenetic studies

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

Applications Engineer

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