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Disrupted brainstem-parahippocampal connectivity identified as a biomarker for delirium

Delirium, commonly observed in critically ill patients following intracerebral hemorrhage (ICH), is an acute neuropsychiatric disorder characterized by disturbances in attention, consciousness, and cognition.

31 Oct 2025

Immune cell dysregulation and inflammatory mediators shape epilepsy risk

Emerging evidence implicates immune dysregulation and neuroinflammation in the pathogenesis of epilepsy, yet the causal mechanisms remain unclear.

31 Oct 2025

First self-powered spinal implant can transmit real-time data from inside the body

A collaboration between civil engineering and neurosurgery at the University of Pittsburgh could change how spinal fusion surgery is performed and monitored. Associate Professors Amir Alavi, Nitin Agarwal, and D. Kojo Hamilton have received a $352,213 National Institutes of Health (NIH) R21 grant to develop the first self-powered spinal implant capable of transmitting real-time data from inside the body.

28 Oct 2025

Mount Sinai receives $4.5 million grant to investigate neural mechanisms underlying bipolar disorder

The Icahn School of Medicine at Mount Sinai is pleased to announce it has received a three-year, $4.5 million grant from BD2: Breakthrough Discoveries for thriving with Bipolar Disorder to investigate the neural mechanisms underlying bipolar disorder and pioneer novel neuromodulation-based treatment strategies.

28 Oct 2025

Excess mortality associated with chronic pain can be avoided through spinal cord stimulation

Treating chronic neuropathic pain with spinal cord stimulation may help prevent excess mortality associated with chronic pain, a new study from the University of Eastern Finland and Kuopio University Hospital shows.

27 Oct 2025

First multiple sclerosis patient in the UK receives CAR T cell therapy in groundbreaking trial

A multiple sclerosis (MS) patient in the UK was the first to receive CAR T cell therapy, invented by UCL researchers, in a clinical trial testing whether this personalized treatment can slow or even halt the progression of the disease.

24 Oct 2025

A parent's guide to manage pediatric respiratory illnesses during the virus season

As we head deeper into fall and toward the holiday season, your little one may start to exhibit symptoms like a runny nose, cough, or fever.

24 Oct 2025

New noninvasive device measures brain blood flow using laser speckle technology

Measuring blood flow in the brain is critical for responding to a range of neurological problems, including stroke, traumatic brain injury (TBI) and vascular dementia.

21 Oct 2025

Tailored deep brain stimulation offers new hope for hard-to-treat epilepsy

Doctors and researchers at the University of Pittsburgh and UPMC have developed a new treatment for epilepsy patients who don't respond to medication and aren't candidates for surgery. Their approach, published today in Nature Communications, uses deep brain stimulation (DBS) that is tailored to each patient's unique brain wiring.

21 Oct 2025

World's largest-ever clinical trial launched to test treatments for Parkinson's disease

The world's largest-ever clinical trial of treatments to slow or stop the progression of Parkinson's disease has launched, led by researchers at UCL and Newcastle University.

16 Oct 2025

Mother's voice promotes development of language pathways in preemies’ brains

Hearing the sound of their mother's voice promotes development of language pathways in a premature baby's brain, according to a new Stanford Medicine-led study.

14 Oct 2025

Researchers uncover possible immune link to chronic pain

University of Arizona researchers may have uncovered a connection between chronic pain and a somewhat uncommon immune condition, opening the door to future research on immune biomarkers for chronic pain.

9 Oct 2025

Engineered virus therapy triggers powerful immune responses in glioblastoma

A new study led by Break Through Cancer's Accelerating Glioblastoma (GBM) Therapies Through Serial Biopsies TeamLab has revealed that an engineered virus therapy, CAN-3110, triggered powerful immune responses deep inside glioblastoma tumors that were invisible to standard imaging like MRI, according to early analyses of two patients with recurrent GBM.

9 Oct 2025

COMBINEDBrain and MUSC join forces to launch pediatric CNS biorepository

COMBINEDBrain, a leader in advancing translational neuroscience research, and the Medical University of South Carolina (MUSC), one of the nation's premier academic health centers, are excited to announce a strategic partnership to establish a cutting-edge biorepository for pediatric central nervous system (CNS) tissue and biofluids.

7 Oct 2025

Deadly brain cancer erodes skull bone and alters immune marrow

Scientists at Montefiore Einstein Comprehensive Cancer Center (MECCC) and Albert Einstein College of Medicine have shown for the first time that glioblastoma-the deadliest form of brain cancer-affects not just the brain but also erodes the skull, alters the makeup of skull marrow, and interferes with the body's immune response.

3 Oct 2025

Emergency departments emerge as key entry point for hospice and palliative care

One-third of Americans will visit an emergency department, or ED, within a month of their death. While EDs are primarily purposed to provide emergent care, they're increasingly becoming an initial touchpoint for hospice and palliative care, or HPC, referrals and consultations, according to a new study from several researchers at Henry Ford Health + Michigan State University Health Sciences.

25 Sep 2025

AstroCapsules offer a new way to reduce brain inflammation

Neuroinflammation is linked to a host of detrimental brain disorders, including Alzheimer's and Parkinson's disease.

25 Sep 2025

Artificial intelligence transforms lumbar spine modeling for faster patient care

Nearly 3 in 10 adults in the United States have experienced lower back pain in any three-month period, making it the most common musculoskeletal pain.

17 Sep 2025

AI tool SeeMe detects hidden signs of consciousness in brain injury patients

A new study published in Nature Communications Medicine led by neurosurgery researchers Sima Mofakham, PhD, and Chuck Mikell, MD, of the Renaissance School of Medicine (RSOM) at Stony Brook University, provides clinicians with data about the path to consciousness after traumatic brain injury (TBI) that may help pave the way for more personalized and effective patient care strategies in critical care and rehabilitation settings.

12 Sep 2025

UCL launches landmark trial of Alzheimer’s blood test

A major UCL-led clinical trial, aiming to transform the diagnosis of Alzheimer's disease through a simple blood test, is now welcoming its first participants who will be recruited via memory clinics across the UK.

11 Sep 2025