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Gene mutation in the brain of autism patients alters behaviors in mice

Autism spectrum disorder (ASD) has a wide range of possible causes, including genetics and environmental factors. Now, a new study suggests that a brain protein mutation may shed light on the mechanism of neurological and developmental illness.

23 Jul 2019

UAB scientists identify new target for drug intervention in Alzheimer's disease

Scientists at the University of Alabama at Birmingham have identified an enzyme in the brain that may be an intriguing target for interventions against Alzheimer's disease and other dementias.

26 Jun 2019

Protein supplements containing BCAA may have ‘detrimental effects’ on health and lifespan

New research suggests that BCAAs in the form of pre-mixed protein powders, shakes and supplements may do more harm to health than good.

1 May 2019

Synthesizing Modified and Pharmaceutically Relevant Peptides

In this interview, CEM Corporation talks to News-Medical Life Sciences about using their product the Liberty Blue for Automated High-Efficiency Solid Phase Peptides Synthesis of Modified and Pharmaceutically Relevant Peptides.

From CEM Corporation - Life Science 24 Apr 2019

Study offers novel insights into how a major tumor suppressor pathway becomes deactivated

The Hippo pathway is an important biological tumor suppressor program that controls cell growth and organ size in humans.

5 Apr 2019

Air pollution linked with development of Alzheimer's in Mexico City children

A new study by researchers at the Universities of Montana, Valle de México, Boise State, Universidad Veracruzana, Instituto Nacional de Pediatría and Paul-Flechsig-Institute for Brain Research heightens together with German company Analytik Jena concerns over the evolving and relentless Alzheimer's pathology observed in young Metropolitan Mexico City urbanites.

21 Dec 2018

Stress related pathway instrumental in controlling function of immune cells

The immune system is composed of a wide range of different immune cells each with dedicated functions. Natural killer T cells form a specialized immune cell that protects against a variety of diseases such as cancer, autoimmunity, metabolic disease or certain infections such as Lyme disease.

20 Dec 2018

Researchers study significance of water in a promising cancer biomarker

The UPV/EHU's Department of Physical Chemistry and the Biofísika Institute have conducted a multidisciplinary study of the Tn antigen that appears in 90% of cancers. Two variants that appear to be similar but which have very different shapes in water have been studied.

26 Oct 2018

Active role of water in a promising biomarker against cancer

The UPV/EHU's Department of Physical Chemistry and the Biofísika Institute have conducted a multidisciplinary study of the Tn antigen that appears in 90% of cancers.

12 Oct 2018

Researchers shed new light on how bacteria sense nutrients in their environment

University of Leicester researchers have shed new light on how bacteria sense nutrients in their environment - which could provide important knowledge in the development of drugs and antibiotics to combat a range of diseases including tuberculosis.

3 Aug 2018

Researchers discover glutamine-dependent activation of cell growth and autophagy

The human body consists of about 35 trillion cells, so it could be said that overall body growth is the growth of individual cells.

3 May 2018

Scientists identify biomarkers that predict risk of death in Ebola patients

Scientists have identified a set of biomarkers that indicate which patients infected with the Ebola virus are most at risk of dying from the disease.

17 Nov 2017

Research reveals sugary secrets of protein important for development and cancer progression

The proteins in human cells are extensively decorated with different types of sugars, a phenomenon called glycosylation. These modifications greatly increase the diversity of protein structure and function, affecting how proteins fold, how they behave, and where they go in cells.

15 Sep 2017

Potential rare gene mutation could act as predictor for schizophrenia and autism

Huntington's disease, cystic fibrosis, and muscular dystrophy are all diseases that can be traced to a single mutation. Diagnosis in asymptomatic patient for these diseases is relatively easy - You have the mutation? Then you are at risk. Complex diseases, on the other hand, do not have a clear mutational footprint.

30 Aug 2017

Study may provide insight into how R-LA promotes death of hepatoma cells

A new study that measured metabolite levels over time in starved rat liver cancer cells showed that treatment with a form of alpha-lipoic acid (LA) inhibited glucose uptake and glycolysis, and led to decreased cellular glucose production from non-carbohydrate sources, which may help explain how the naturally occurring R enantiomeric form of LA (R-LA) promotes the death of hepatoma cells.

12 Apr 2017

EPFL scientists develop synthetic methods to crack code of Huntington's disease

Huntington's disease is a neurodegenerative disorder that causes patients to lose their ability to move, speak, and even think. It is caused by a gene mutation that produces an abnormal form of the protein huntingtin, which aggregates and builds up inside neurons of the cortex and striatum.

23 Mar 2017

New study looks to saliva of humans and primates to gain insights into evolution

There's no need to reinvent the genetic wheel. That's one lesson of a new study that looks to the saliva of humans, gorillas, orangutans, macaques and African green monkeys for insights into evolution.

25 Aug 2016

Scientists identify two enzymes that appear to play role in metabolism, inflammation

A team led by scientists at The Scripps Research Institute and the Salk Institute for Biological Studies has discovered two enzymes that appear to play a role in metabolism and inflammation—and might someday be targeted with drugs to treat type 2 diabetes and inflammatory disorders.

29 Mar 2016

Food-based proteins can help address child malnutrition in developing countries

Contrary to popular belief among world relief workers, children in developing countries may not be eating enough protein, which could contribute to stunted growth, a Johns Hopkins-directed study suggests.

24 Feb 2016

New study finds link between maternal protein deficiency during pregnancy and metabolic diseases in offspring

A new study has uncovered the genetic processes that link insufficient protein consumption during pregnancy with the development of muscle problems in mothers and their male offspring.

19 Sep 2015