Uric Acid News and Research

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Newly identified target may lead to discovery of treatments for chronic inflammatory diseases

Inflammation is part of the body's natural healing process. But when it becomes chronic, inflammation can lead to cancer, Alzheimer's disease and other conditions.

26 Jul 2018

AbbVie submits supplemental NDA to FDA for venetoclax to treat acute myeloid leukemia

AbbVie, a research-based global biopharmaceutical company, today announced it submitted a supplemental New Drug Application to the U.S. Food and Drug Administration for venetoclax in combination with a hypomethylating agent or in combination with low-dose cytarabine for the treatment of newly diagnosed patients with acute myeloid leukemia who are ineligible for intensive chemotherapy.

20 Jul 2018

Canakinumab reduces gout rate by more than half in atherosclerosis patients, study shows

The results of a study presented today at the Annual European Congress of Rheumatology (EULAR 2018) demonstrate that canakinumab significantly reduced the rate of gout by more than half compared to placebo, regardless of baseline serum urate level.

18 Jun 2018

Study shows improvements in adherence, outcomes of gout patients receiving text message reminders

The results of a study presented today at the Annual European Congress of Rheumatology (EULAR 2018) demonstrate significant improvements in adherence and clinical outcomes in gout patients who received a daily text message to remind them to take allopurinol.

14 Jun 2018

Kidney stones on the rise among Americans, finds study

According to a new study, there is an increasing incidence of kidney stones among men and women living in the United States. The study is published this week in the latest issue of the journal Mayo Clinic Proceedings.

14 Feb 2018

Self-powered, paper-based electrochemical devices detect biomarkers and identify diseases

A new medical-diagnostic device made out of paper detects biomarkers and identifies diseases by performing electrochemical analyses - powered only by the user's touch - and reads out the color-coded test results, making it easy for non-experts to understand.

22 Aug 2017

Titanium dioxide nanoparticles can intensify inflammatory reaction in patients with colitis

Titanium dioxide, one of the most-produced nanoparticles worldwide, is being used increasingly in foodstuffs.

19 Jul 2017

Combination treatment found to effective in patients with tophaceous gout

The drug lesinurad in combination with febuxostat was better at lowering blood levels of urate than febuxostat alone in a phase III clinical trial of 324 patients with tophaceous gout.

9 Jun 2017

Integrated disease management approach may benefit patients with CKD and gout, study suggests

A large-scale study examining the link between uncontrolled gout and the progression of chronic kidney disease (CKD) suggests that using an integrated disease management approach may help prevent the progression of CKD in these patients.

19 Apr 2017

Increased uric acid levels in early life may lead to high blood pressure later on

A new article published in the American Journal of Hypertension finds that very young children with increased uric acid levels had higher blood pressure at 3 years of age.

15 Mar 2017

Mice study shows role of yeast in aggravating IBD symptoms

During the past decade, the gut has experienced a renaissance as investigations focus on the role of the microbiome on human health.

8 Mar 2017

Dietary fructose consumption may increase risk for NASH in children and adolescents

Recent research suggests that dietary fructose intake may increase serum uric acid concentrations and that both uric acid concentration and fructose consumption may be increased in individuals with non-alcoholic fatty liver disease.

14 Feb 2017

Elevated urate levels linked to musculo-skeletal pain

Episodes of diffuse musculo-skeletal pain appearing in and around a joint region without a clear diagnosis, etiology and therapy are still a major problem in general medical practice.

29 Nov 2016

Scientists develop mechanically stable, disposable sensor for monitoring heart attacks

Blood-glucose monitoring devices have revolutionized the management of diabetes by making it easy for ordinary individuals to test their glucose levels at home.

14 Oct 2016

NYU Lutheran offers many treatment options for kidney stone sufferers

Frederick A. Gulmi, MD, chief of urology at NYU Lutheran, cautions anyone who has never had a bout with kidney stones.

24 Aug 2016

DASH diet could be effective, non-pharmacologic approach to prevent gout flares

New research indicates that a healthy diet can effectively lower blood levels of uric acid, a known trigger of gout. The findings are published in Arthritis & Rheumatology, a journal of the American College of Rheumatology .

16 Aug 2016

Preclinical data on Selecta’s novel immune tolerance platform published in Nature Nanotechnology

Selecta Biosciences, Inc., a clinical-stage biopharmaceutical company developing targeted antigen-specific immune therapies for rare and serious diseases, announced today that Nature Nanotechnology has published an article that presents preclinical results from Selecta’s research which demonstrate the broad potential applicability of Selecta’s novel immune tolerance platform.

2 Aug 2016

European Commission approves extended indication for Amgen's Kyprolis (carfilzomib) for the treatment of relapsed multiple myeloma patients

Amgen has announced that the European Commission (EC) has approved a variation to the marketing authorization for Kyprolis® (carfilzomib) to include use in combination with dexamethasone alone for adult patients with multiple myeloma who have received at least one prior therapy. The extended indication marks the second approval for Kyprolis by the EC in less than a year.

6 Jul 2016

Study finds differences in hospitalization trends for gout and rheumatoid arthritis

While hospitalizations related to rheumatoid arthritis have dropped considerably over the past two decades, hospitalizations primarily associated with gout have increased dramatically.

8 Jun 2016

Dr Anjali Mahto explains how to prevent risk of mosquito bites

Nobody likes being bitten by mosquitos whether it’s at home or abroad. Consultant Dermatologist & British Skin Foundation spokesperson, Dr Anjali Mahto explains how to deter the summer pests, what to do when bitten and why they are attracted to us in the first place.

2 Jun 2016