Antibiotic News and Research

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Antibiotics are drugs used to treat infections caused by bacteria and other microorganisms.

Mouthwashes inhibit the infectivity of SARS-CoV-2 variants

SARS-CoV-2, the virus that causes COVID-19, is an airborne disease transmitted via aerosols, which are spread from the oral and nasal cavities - the mouth and the nose.

6 Oct 2022

Routine newborn screening for sickle cell disease urgently needed to save lives in Africa

More than 300,000 babies globally are born every year with sickle cell, a hereditary condition which causes red blood cells to become sickle-shaped.

5 Oct 2022

Early-stage clinical trial evaluating bacteriophage therapy in adults with cystic fibrosis begins

Enrollment has begun in an early-stage clinical trial evaluating bacteriophage therapy in adults with cystic fibrosis (CF) who carry Pseudomonas aeruginosa (P. aeruginosa) in their lungs.

4 Oct 2022

The compositional and functional diversity of the gut fungal microbiome

Researchers assessed the role of gut bacterial microbiome assembly and the gut mycobiome in relation to health, pathology, and clinical applications.

30 Sep 2022

DNA metagenomic analyses of clinical samples from Monkeypox virus-infected individuals

Researchers analyzed genomic sequences of MPXV obtained from 18 patients who contracted MPXV infection between June and July 2022.

30 Sep 2022

New capsule tunnels through mucus in the GI tract to deliver large protein drugs

One reason that it's so difficult to deliver large protein drugs orally is that these drugs can't pass through the mucus barrier that lines the digestive tract.

28 Sep 2022

Orally ingestible robotic drug delivery device overcomes barriers of the gastrointestinal environment

Oral drug delivery is the most common and cost-effective way to deliver a treatment. But drugs must make it through the harsh, acidic environment of the stomach, resist degradation by enzymes, penetrate the barrier posed by the mucus of the small intestine and overcome many other obstacles before they can be absorbed.

28 Sep 2022

Scientists visualize antibiotics in action inside a pathogenic bacterium

Every living cell relies on proteins in order to function and the process of protein synthesis – translation – is critical for survival.

28 Sep 2022

Bile acids play an important role in regulating gut microbiome

Scientists performe in vitro and in vivo experiments to investigate the antimicrobial effects of different bile acids on various microorganisms.

27 Sep 2022

How the gut microbiome could affect COVID-19 severity

Researchers review the potential role of the gut microbiome in determining severe COVID-19.

27 Sep 2022

Study identifies potential therapeutic targets for preventing aminoglycoside-induced hearing loss

Researchers at Indiana University School of Medicine are developing new ways to study why an antibiotic causes hair cell death and permanent hearing loss in people.

27 Sep 2022

New engineered peptides could prevent the superbug crisis

A recent study reports the development of a synthetic antibacterial peptide PLG0206.

22 Sep 2022

Genome-based microbiome signature associated with the severity and prognosis of COVID-19 in hospitalized patients

Researchers evaluated the association between guild-level microbiome signature and the severity and prognosis of SARS-CoV-2 infections by a genome-level metagenomic analysis.

21 Sep 2022

Link between type 2 diabetes and UTIs explained

Lower immunity and recurring infections are common in type 1 and type 2 diabetes. Researchers at Karolinska Institutet in Sweden now show that the immune system of people with diabetes has lower levels of the antimicrobial peptide psoriasin, which compromises the urinary bladder's cell barrier, increasing the risk of urinary tract infection.

20 Sep 2022

Soy protein diet increases susceptibility to Clostridioides difficile infection

According to a recent study published in the journal Cell Reports, a diet rich in soy protein increases human Clostridioides difficile susceptibility by increasing the gut amino acids (AAs) levels and promoting the growth of Lactobacillus.

18 Sep 2022

Higher levels of microbiota engraftment linked to greater chances of transplantation success

From incurable intestinal infections to metabolic syndrome, from melanoma, to chronic inflammatory bowel disease, such as irritable bowel syndrome, to Tourette's syndrome: many diseases can potentially be cured by Fecal Microbiota Transplantation (FMT), and researchers from the Catholic University, Rome and the University of Trento have shown that the greater the level of engraftment of the transplanted microorganisms, the greater the chances of success of the therapy.

15 Sep 2022

Manuka honey could cure serious lung infections caused by drug-resistant bacterium

In a recent study published in the journal Microbiology, researchers demonstrated that incorporating Manuka honey into nebulized antibiotic treatment could effectively combat respiratory infections due to Mycobacterium abscessusus, offering a novel new therapeutic strategy for M. abscessus management.

13 Sep 2022

The impact of the infant gut microbiome on vaccine efficacy

A new study reports the effect of the infant gut microbiome on vaccine efficacy.

13 Sep 2022

Antibiotics accelerate metastatic bone growth in mice with melanoma by depleting intestinal flora

The use of broad-spectrum antibiotics in mice with malignant melanoma, an aggressive form of skin cancer, accelerated their metastatic bone growth, likely because the drugs depleted the mice's intestinal flora and weakened their immune response, according to a new study by researchers at Emory University in Atlanta.

12 Sep 2022

Early life exposure to antibiotics can have long-lasting effects on adult gut health

Preterm and low birth weight babies are routinely given antibiotics to prevent, not just treat, infections, which they have a high risk of developing.

9 Sep 2022

Antibiotic News and Research

Further Reading

Mouthwashes inhibit the infectivity of SARS-CoV-2 variants

Routine newborn screening for sickle cell disease urgently needed to save lives in Africa

Early-stage clinical trial evaluating bacteriophage therapy in adults with cystic fibrosis begins

The compositional and functional diversity of the gut fungal microbiome

DNA metagenomic analyses of clinical samples from Monkeypox virus-infected individuals

New capsule tunnels through mucus in the GI tract to deliver large protein drugs

Orally ingestible robotic drug delivery device overcomes barriers of the gastrointestinal environment

Scientists visualize antibiotics in action inside a pathogenic bacterium

Bile acids play an important role in regulating gut microbiome

How the gut microbiome could affect COVID-19 severity

Study identifies potential therapeutic targets for preventing aminoglycoside-induced hearing loss

New engineered peptides could prevent the superbug crisis

Genome-based microbiome signature associated with the severity and prognosis of COVID-19 in hospitalized patients

Link between type 2 diabetes and UTIs explained

Soy protein diet increases susceptibility to Clostridioides difficile infection

Higher levels of microbiota engraftment linked to greater chances of transplantation success

Manuka honey could cure serious lung infections caused by drug-resistant bacterium

The impact of the infant gut microbiome on vaccine efficacy

Antibiotics accelerate metastatic bone growth in mice with melanoma by depleting intestinal flora

Early life exposure to antibiotics can have long-lasting effects on adult gut health

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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