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Scientists design new drugs that may help prevent spread of aggressive pancreatic cancers

Cancer is among the leading causes of death worldwide> There were approximately 14m new cases diagnosed and 8.2m cancer related deaths in 2012. This figure is expected to rise of about 70% over the next two decades.

13 Feb 2017

Study reveals new role for cancer drug in tumor immunology

A drug first designed to prevent cancer cells from multiplying has a second effect: it switches immune cells that turn down the body's attack on tumors back into the kind that amplify it. This is the finding of a study led by researchers from NYU Langone Medical Center and published recently in Cancer Immunology Research.

13 Feb 2017

New discovery could lead to more effective malaria vaccine

A team at the Wellcome Trust Sanger Institute has discovered how a promising malarial vaccine target - the protein RH5 - helps parasites to invade human red blood cells.

11 Feb 2017

Research uncovers previously unknown mechanism that could be key to alternative lupus treatment

Only one new drug has become available over the past 50 years for the estimated 1.5 million Americans and five million-plus people worldwide suffering from lupus, but new research has identified a previously unknown mechanism involved in the immune response that could provide an alternative therapy target.

10 Feb 2017

Regular intake of prebiotics may promote recovery of normal sleep patterns after stress

What are some ways you cope with stresses in your life? Do you do yoga? Meditate? Exercise? Perhaps you should add taking prebiotics to that list.

10 Feb 2017

VIB-KU Leuven researchers identify underlying mechanism in early onset Parkinson's disease

A team of researchers led by Patrik Verstreken have identified an underlying mechanism in early onset Parkinson's.

10 Feb 2017

Research suggests new type of congenital muscular dystrophy

A newly discovered mutation in the INPP5K gene, which leads to short stature, muscle weakness, intellectual disability, and cataracts, suggests a new type of congenital muscular dystrophy.

10 Feb 2017

Malaria mosquitoes exhibit similar sensitivity to heat and horseradish

Researchers at Lund University in Sweden have taken an important step on the road to understanding the underlying mechanism of how and why animals can feel pain in connection with cold or heat. However, according to the study, temperature is just one triggering factor – horseradish, mustard, cinnamon and wasabi have a similar effect.

10 Feb 2017

Consuming whole grains has modest effects on gut microbiota and immune response, study finds

In a clinical trial, adults who consumed a diet rich in whole grains rather than refined grains had modest improvements in healthy gut microbiota and certain immune responses. The research was conducted in tandem with a study that looked at the effects of a whole-grain diet on energy metabolism.

9 Feb 2017

FDA approves new treatment for wide range of patients with Duchenne muscular dystrophy

The U.S. Food and Drug Administration today approved Emflaza (deflazacort) tablets and oral suspension to treat patients age 5 years and older with Duchenne muscular dystrophy (DMD), a rare genetic disorder that causes progressive muscle deterioration and weakness.

9 Feb 2017

Scientists identify vulnerabilities of highly aggressive pancreatic cancer cells

Researchers have identified a gatekeeper protein that prevents pancreatic cancer cells from transitioning into a particularly aggressive cell type and also found therapies capable of thwarting those cells when the gatekeeper is depleted.

9 Feb 2017

Scientists identify gene variants that predispose children to developing Kawasaki disease

Kawasaki disease (KD) is the most common acquired heart disease in children. Untreated, roughly one-quarter of children with KD develop coronary artery aneurysms -- balloon-like bulges of heart vessels -- that may ultimately result in heart attacks, congestive heart failure or sudden death.

9 Feb 2017

Study suggests new ways to treat neurological symptoms linked to tuberous sclerosis complex

Boston Children's Hospital researchers have uncovered a new molecular pathway that inhibits the myelination of neurons in the brains of patients with the rare genetic disorder tuberous sclerosis complex.

9 Feb 2017

Researchers identify E. coli bacteria linking Crohn's disease to spondyloarthritis

Patients with Crohn's disease, a type of inflammatory bowel disease (IBD) that causes abdominal pain and diarrhea, can also experience joint pain.

9 Feb 2017

Researchers shed light on how IFT20 protein helps some cancer cells to invade

An international research team has discovered that the IFT20 protein helps some cancer cells to invade by facilitating the transportation of membranes and proteins within parts of the cell.

9 Feb 2017

Exosome isolation using ultracentrifugation

In the outpatient clinic and lab, our research studies aim to understand biological functions of exosomes and membrane particles.

From Beckman Coulter Life Sciences - Centrifugation 9 Feb 2017

UMass Amherst discovery holds promise for revolutionizing treatment of cataracts and presbyopia

The University of Massachusetts Amherst recently licensed a new technology to Janssen Pharmaceuticals, Inc. that holds promise of revolutionizing the treatment of cataracts and presbyopia, based on early phase discoveries by polymer physicist Murugappan Muthukumar and former graduate student Ben Mohr regarding the fundamental science of proteins in the lens of the human eye.

9 Feb 2017

Scientists develop computer models to predict mutations’ effect on pairs of proteins

According to new research, the key to a successful, long-term relationship is for each partner to adapt to the other's changes over time.

9 Feb 2017

Simple blood test may be accurate in differentiating between Parkinson's disease and APDs

A simple blood test may be as accurate as a spinal fluid test when trying to determine whether symptoms are caused by Parkinson's disease or another atypical parkinsonism disorder, according to a new study published in the February 8, 2017, online issue of Neurology, the medical journal of the American Academy of Neurology.

9 Feb 2017

New therapeutic agent shows potential for treating optic neuritis linked to multiple sclerosis

A new therapeutic agent tested in a mouse model of multiple sclerosis (MS) produced anti-inflammatory activity and prevented loss of cells in the optic nerve, according to a new study by researchers in the Perelman School of Medicine at the University of Pennsylvania, with Pittsburgh-based Noveome Biotherapeutics.

9 Feb 2017

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G Protein News and Research

Scientists design new drugs that may help prevent spread of aggressive pancreatic cancers

Study reveals new role for cancer drug in tumor immunology

New discovery could lead to more effective malaria vaccine

Research uncovers previously unknown mechanism that could be key to alternative lupus treatment

Regular intake of prebiotics may promote recovery of normal sleep patterns after stress

VIB-KU Leuven researchers identify underlying mechanism in early onset Parkinson's disease

Research suggests new type of congenital muscular dystrophy

Malaria mosquitoes exhibit similar sensitivity to heat and horseradish

Consuming whole grains has modest effects on gut microbiota and immune response, study finds

FDA approves new treatment for wide range of patients with Duchenne muscular dystrophy

Scientists identify vulnerabilities of highly aggressive pancreatic cancer cells

Scientists identify gene variants that predispose children to developing Kawasaki disease

Study suggests new ways to treat neurological symptoms linked to tuberous sclerosis complex

Researchers identify E. coli bacteria linking Crohn's disease to spondyloarthritis

Researchers shed light on how IFT20 protein helps some cancer cells to invade

Exosome isolation using ultracentrifugation

UMass Amherst discovery holds promise for revolutionizing treatment of cataracts and presbyopia

Scientists develop computer models to predict mutations’ effect on pairs of proteins

Simple blood test may be accurate in differentiating between Parkinson's disease and APDs

New therapeutic agent shows potential for treating optic neuritis linked to multiple sclerosis

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